Search Results - "Wang, Xunjiang"
-
1
Notoginsenoside Ft1 acts as a TGR5 agonist but FXR antagonist to alleviate high fat diet-induced obesity and insulin resistance in mice
Published in Acta pharmaceutica Sinica. B (01-06-2021)“…Obesity and its associated complications are highly related to a current public health crisis around the world. A growing body of evidence has indicated that…”
Get full text
Journal Article -
2
Integrative analysis of renal microRNA and mRNA to identify hub genes and pivotal pathways associated with cyclosporine-induced acute kidney injury in mice
Published in Human & experimental toxicology (01-11-2023)“…Cyclosporine (CsA) is an immunosuppressive agent that often causes acute kidney injury (AKI) in children. The specific mechanisms underlying CsA-induced AKI…”
Get full text
Journal Article -
3
Hyperoside attenuates pyrrolizidine alkaloids-induced liver injury by ameliorating TFEB-mediated mitochondrial dysfunction
Published in Archives of pharmacal research (01-08-2023)“…Pyrrolizidine alkaloids (PAs) are potent hepatotoxins that can cause liver damage. Hyperoside (Hyp), a natural flavonoid, can be extracted from medicinal…”
Get full text
Journal Article -
4
Black ginseng extract attenuates high-fat diet-induced obesity by stimulating ileal TGR5 activation and modulating gut microbiota
Published in Journal of functional foods (01-06-2024)“…[Display omitted] •Black ginseng extract (BGS) ameliorated obesity in diet-induced obese (DIO) mice.•A combination of 70% and 95% ethanol extracts of Black…”
Get full text
Journal Article -
5
Blood microRNA Signatures Serve as Potential Diagnostic Biomarkers for Hepatic Sinusoidal Obstruction Syndrome Caused by Gynura japonica Containing Pyrrolizidine Alkaloids
Published in Frontiers in pharmacology (19-02-2021)“…The -induced hepatic sinusoidal obstruction syndrome (HSOS) is closely related to pyrrolizidine alkaloids (PAs), and its prevalence has been increasing…”
Get full text
Journal Article -
6
Comprehensive profiling of amino acids and derivatives in biological samples: A robust UHPLC-MS/MS method for investigating acute lung injury
Published in Journal of Chromatography A (26-04-2024)“…•A rapid UPLC-MS/MS method was developed for quantification of 48 amino acids and derivatives.•The method can be applied to mouse plasma, urine and lung tissue…”
Get full text
Journal Article -
7
Pharmacological mechanisms of traditional Chinese medicine against acute lung injury: From active ingredients to herbal formulae
Published in Phytomedicine (Stuttgart) (01-12-2024)“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the leading causes of acute respiratory failure in many critical diseases and are…”
Get full text
Journal Article -
8
Red ginseng extracts ameliorate high-fat diet-induced obesity and insulin resistance by activating the intestinal TGR5-mediated bile acids signaling pathway
Published in Phytomedicine (Stuttgart) (01-10-2023)“…Obesity has emerged as a worldwide metabolic disease, given its rapid growth in global prevalence. Red ginseng extracts (RGS), one of the traditional processed…”
Get full text
Journal Article -
9
Shengmai San formula alleviates high-fat diet-induced obesity in mice through gut microbiota-derived bile acid promotion of M2 macrophage polarization and thermogenesis
Published in Phytomedicine (Stuttgart) (01-10-2024)“…Shengmai San Formula (SMS) is a traditional Chinese medicine (TCM) that has been used to treat wasting-thirst regarded as diabetes mellitus, which occurs…”
Get full text
Journal Article -
10
Functional metabolomics characterizes the contribution of farnesoid X receptor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome
Published in Archives of toxicology (01-08-2024)“…Consumption of herbal products containing pyrrolizidine alkaloids (PAs) is one of the major causes for hepatic sinusoidal obstruction syndrome (HSOS), a deadly…”
Get full text
Journal Article -
11
Biological functions and pharmacological behaviors of bile acids in metabolic diseases
Published in Journal of advanced research (08-11-2024)“…[Display omitted] •Functional bile acids (BAs) reveal diverse pharmacological activities attributed to their unique structural variations.•BA receptors mediate…”
Get full text
Journal Article -
12
A TMT-based shotgun proteomics uncovers overexpression of thrombospondin 1 as a contributor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome
Published in Archives of toxicology (01-07-2022)“…Hepatic sinusoidal obstruction disease (HSOS) is a rare but life-threatening vascular liver disease. However, its underlying mechanism and molecular changes in…”
Get full text
Journal Article -
13
Validation of the Nanjing Criteria for Diagnosing Pyrrolizidine Alkaloids-induced Hepatic Sinusoidal Obstruction Syndrome
Published in Journal of clinical and translational hepatology (28-06-2021)“…Hepatic sinusoidal obstruction syndrome (HSOS) is caused by toxic injury to sinusoidal endothelial cells in the liver. The intake of pyrrolizidine alkaloids…”
Get full text
Journal Article