Search Results - "Wang, Xipei"

Exploring the causal effects of the gut microbiome on serum lipid levels: A two-sample Mendelian randomization analysis by Guo, Gongjie, Wu, Yonglin, Liu, Yingjian, Wang, Zixian, Xu, Guifeng, Wang, Xipei, Liang, Feiqing, Lai, Weihua, Xiao, Xiao, Zhu, Qian, Zhong, Shilong

“…The gut microbiome was reported to be associated with dyslipidemia in previous observational studies. However, whether the composition of the gut microbiome…”
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Joint population pharmacokinetic modeling of venlafaxine and O-desmethyl venlafaxine in healthy volunteers and patients to evaluate the impact of morbidity and concomitant medication by Wang, Zhanzhang, Li, Lu, Huang, Shanqing, Wang, Xipei, Liu, Shujing, Li, Xiaolin, Kong, Wan, Ni, Xiaojia, Zhang, Ming, Huang, Shanshan, Tan, Yaqian, Wen, Yuguan, Shang, Dewei

“…Venlafaxine (VEN) is a widely used dual selective serotonin/noradrenaline reuptake inhibitor indicated for depression and anxiety. It undergoes first-pass…”
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Pharmacokinetic and Pharmacogenetic Factors Contributing to Platelet Function Recovery After Single Dose of Ticagrelor in Healthy Subjects by Zhu, Qian, Zhong, Wanping, Wang, Xipei, Mai, Liping, He, Guodong, Chen, Jiyan, Tang, Lan, Liu, Shuwen, Lai, Weihua, Zhong, Shilong

“…This study aimed to elucidate the contribution of candidate single nucleotide polymorphisms (SNPs) related to pharmacokinetics on the recovery of platelet…”
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The Determination of Polymyxin B in Critically Ill Patients by the HPLC-MS/MS Method by Wang, Yirong, Chen, Jingchun, Du, Jinpan, Lei, Liming, Zhao, Boxin, Bai, Yunpeng, Chen, Dong, Wang, Xipei, Chen, Chunbo

“…Polymyxin B (PB) is a dose-dependent drug used to treat multidrug-resistantgram-negative bacteria, for which a suitable method is needed to determine clinical…”
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Estimation of Mycophenolic Acid Exposure in Heart Transplant Recipients by Population Pharmacokinetic and Limited Sampling Strategies by Wang, Xipei, Wu, Yijin, Huang, Jinsong, Shan, Songgui, Mai, Mingjie, Zhu, Jiade, Yang, Min, Shang, Dewei, Wu, Zheng, Lan, Jinhua, Zhong, Shilong, Wu, Min

“…The aim of this study is i) to establish a strategy to estimate the area under the curve of the dosing interval (AUC ) of mycophenolic acid (MPA) in the heart…”
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Development and Validation of an HPLC-MS/MS Method for Rapid Simultaneous Determination of Cefprozil Diastereomers in Human Plasma by He, Guodong, Wang, Xipei, Mai, Liping

“…Background. Both cis- and trans-cefprozil have antimicrobial activity, but their potencies are quite different. It is therefore necessary to develop a…”
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Combining Metabolomics and Interpretable Machine Learning to Reveal Plasma Metabolic Profiling and Biological Correlates of Alcohol-Dependent Inpatients: What About Tryptophan Metabolism Regulation? by Zhu, Xiuqing, Huang, Jiaxin, Huang, Shanqing, Wen, Yuguan, Lan, Xiaochang, Wang, Xipei, Lu, Chuanli, Wang, Zhanzhang, Fan, Ni, Shang, Dewei

“…Alcohol dependence (AD) is a condition of alcohol use disorder in which the drinkers frequently develop emotional symptoms associated with a continuous alcohol…”
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Preclinical Pharmacokinetic/Pharmacodynamic Models to Predict Schedule-Dependent Interaction Between Erlotinib and Gemcitabine by Li, Mengyao, Li, Hanqing, Cheng, Xiaoliang, Wang, Xipei, Li, Liang, Zhou, Tianyan, Lu, Wei

“…Purpose To investigate the pharmacological effects of different erlotinib (ER) and gemcitabine (GM) combination schedules by in vitro and in vivo experiments…”
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Application of model-based methods to characterize exenatide-loaded double-walled microspheres: in vivo release, pharmacokinetic/pharmacodynamic model, and in vitro and in vivo correlation by Li, Xingang, Li, Liang, Wang, Xipei, Ren, Yupeng, Zhou, Tianyan, Lu, Wei

“…The objective of this study was to characterize exenatide double-walled microspheres (DWMS) using model-based methods. Exenatide DWMS were prepared using…”
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Establishment and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Tigecycline in Critically Ill Patients by Chen, Chunbo, Wu, Zheng, Lan, Jinhua, Wang, Xipei, Hou, Yating, Wang, Yifan, Yao, Fen, Wang, Yirong

“…Utilizing tigecycline-d9 as an internal standard (IS), we establish and validate a simple, effective, and rapid liquid chromatography-tandem mass spectrometry…”
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Rapid determination of fenoldopam in human plasma by UPLC–MS/MS for pharmacokinetic analysis in patients by Wang, Xipei, Zheng, Zhijie, He, Guodong, Mai, Liping, Zhou, Zhiling, Zhong, Shilong, Lin, Qiuxiong, Shan, Zhixin, Deng, Chunyu, Yang, Min, Yu, Xiyong

“…•We developed a rapid UPLC–MS/MS method for quantifying fenoldopam in human plasma.•The matrix effect and stability of fenoldopam in hemolyzed plasma was…”
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Simultaneous determination of nitrendipine and hydrochlorothiazide in spontaneously hypertensive rat plasma using HPLC with on-line solid-phase extraction by Shang, Dewei, Wang, Xipei, Zhao, Xiutai, Huang, Fengming, Tian, Ganzhong, Lu, Wei, Zhou, Tianyan

“…► Simultaneous determination of two chemical compounds with different polarity and solubility (NTDP and HCTZ) in SHR plasma using HPLC with on-line solid-phase…”
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Placebo effect model in asthma clinical studies: longitudinal meta-analysis of forced expiratory volume in 1 second by Wang, Xipei, Shang, Dewei, Ribbing, Jakob, Ren, Yupeng, Deng, Chenhui, Zhou, Tianyan, Guo, Feng, Lu, Wei

“…Objective Our objective was to describe the time course of the placebo effect in asthma and quantitatively investigate the affective factors of the placebo…”
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Perfluorooctane sulfonate (PFOS) disrupts testosterone biosynthesis via CREB/CRTC2/StAR signaling pathway in Leydig cells by Qiu, Lianglin, Wang, Hongxia, Dong, Tianyi, Huang, Jiyan, Li, Ting, Ren, Hang, Wang, Xipei, Qu, Jianhua, Wang, Shoulin

“…•PFOS triggers activation of p38, PKA and CREB in vivo and in vitro.•PFOS decrease the expression of CRTC2 and StAR in mice testes.•PFOS inhibits the…”
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Population Pharmacokinetics of Caspofungin and Dose Simulations in Heart Transplant Recipients by Wu, Zheng, Lan, Jinhua, Wang, Xipei, Wu, Yijin, Yao, Fen, Wang, Yifan, Zhao, Bo-Xin, Wang, Yirong, Chen, Jingchun, Chen, Chunbo

“…The effect of heart transplantation (HTx) on the pharmacokinetics (PK) of caspofungin is not well-characterized. The aim of this study was to investigate the…”
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Development and validation of an HPLC-MS/MS assay for the quantitative analysis of remimazolam in critically ill patients by Chen, Jingchun, Wu, Meifen, Xiao, Yumei, Chen, Dong, Wang, Yirong, Bai, Yunpeng, Wang, Xipei, Hu, Linhui, Huang, Rongrong, Chen, Chunbo, Lai, Weihua

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Population pharmacokinetics of posaconazole in Chinese pediatric patients with acute leukaemia: Effect of food on bioavailability and dose optimization by Lin, Danna, Yu, Lihua, Shang, Dewei, Huang, Lulu, Wu, Li, Liao, Xu, Zhang, Yajie, Zi, Juan, Zhang, Jingxin, Zeng, Yinghua, Wang, Xipei, Yang, Lihua

“…1What is already known about this subject:•Posaconazole as a primary antifungal prophylaxis has been verified safe and effective in children during…”
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Perfluorooctane sulfonate induces suppression of testosterone biosynthesis via Sertoli cell-derived exosomal/miR-9-3p downregulating StAR expression in Leydig cells by Huang, Jiyan, Ren, Hang, Chen, Anni, Li, Ting, Wang, Hongxia, Jiang, Lianlian, Zheng, Shaokai, Qi, Han, Ji, Binyan, Wang, Xipei, Qu, Jianhua, Zhao, Jianya, Qiu, Lianglin

“…Perfluorooctane sulfonate (PFOS) is associated with male reproductive disorder, but the related mechanisms are still unclear. In this study, we used in vivo…”
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Learning Nonstationary Time-Series With Dynamic Pattern Extractions by Wang, Xipei, Zhang, Haoyu, Zhang, Yuanbo, Wang, Meng, Song, Jiarui, Lai, Tin, Khushi, Matloob

“…The era of information explosion had prompted the accumulation of a tremendous amount of time-series data, including stationary and nonstationary time-series…”
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Simultaneous Determination of Ticagrelor and Its Metabolites in Human Plasma and Urine Using Liquid Chromatography–Tandem Mass Spectrometry by Zhong, Wanping, Wang, Xipei, Tang, Lan, Mai, Liping, Chen, Xiao-Ping, He, Guodong, Zheng, Zhijie, Zhong, Shilong

“…We have developed and validated a rapid, selective and sensitive method using high-performance liquid chromatography–tandem mass spectrometry (MS) for the…”
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