Search Results - "Wang, Xin W."

Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma by Nepal, Chirag, O'Rourke, Colm J., Oliveira, Douglas V.N.P., Taranta, Andrzej, Shema, Steven, Gautam, Prson, Calderaro, Julien, Barbour, Andrew, Raggi, Chiara, Wennerberg, Krister, Wang, Xin W., Lautem, Anja, Roberts, Lewis R., Andersen, Jesper B.

“…Intrahepatic cholangiocarcinoma remains a highly heterogeneous malignancy that has eluded effective patient stratification to date. The extent to which such…”
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Integrated proteotranscriptomics of breast cancer reveals globally increased protein-mRNA concordance associated with subtypes and survival by Tang, Wei, Zhou, Ming, Dorsey, Tiffany H, Prieto, DaRue A, Wang, Xin W, Ruppin, Eytan, Veenstra, Timothy D, Ambs, Stefan

“…Transcriptome analysis of breast cancer discovered distinct disease subtypes of clinical significance. However, it remains a challenge to define disease…”
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Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer by Cairo, Stefano, Wang, Yipeng, de Reyniès, Aurélien, Duroure, Karine, Dahan, Jennifer, Redon, Marie-José, Fabre, Monique, McClelland, Michael, Wang, Xin W., Croce, Carlo M., Buendia, Marie-Annick, Vogt, Peter K.

“…Myc activation has been implicated in the pathogenesis of hepatoblastoma (HB), a rare embryonal neoplasm derived from liver progenitor cells. Here, microRNA…”
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Identification of drivers from cancer genome diversity in hepatocellular carcinoma by Takai, Atsushi, Dang, Hien T, Wang, Xin W

“…Hepatocellular carcinoma (HCC) is one of the most common cancers with a dismal outcome. The complicated molecular pathogenesis of HCC caused by tumor…”
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Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma by Ji, Junfang, Yamashita, Taro, Wang, Xin W

“…Hepatocellular carcinoma (HCC) is a malignant cancer with an observable heterogeneity and microRNAs are functionally associated with the tumorigenesis of HCC…”
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The clinical potential of microRNAs by Budhu, Anuradha, Ji, Junfang, Wang, Xin W

“…MicroRNAs are small noncoding RNAs that function to control gene expression. These small RNAs have been shown to contribute to the control of cell growth,…”
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Serum proteomics links suppression of tumor immunity to ancestry and lethal prostate cancer by Minas, Tsion Zewdu, Candia, Julián, Dorsey, Tiffany H., Baker, Francine, Tang, Wei, Kiely, Maeve, Smith, Cheryl J., Zhang, Amy L., Jordan, Symone V., Obadi, Obadi M., Ajao, Anuoluwapo, Tettey, Yao, Biritwum, Richard B., Adjei, Andrew A., Mensah, James E., Hoover, Robert N., Jenkins, Frank J., Kittles, Rick, Hsing, Ann W., Wang, Xin W., Loffredo, Christopher A., Yates, Clayton, Cook, Michael B., Ambs, Stefan

“…There is evidence that tumor immunobiology and immunotherapy response may differ between African American and European American prostate cancer patients. Here,…”
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Urinary Metabolites Diagnostic and Prognostic of Intrahepatic Cholangiocarcinoma by Haznadar, Majda, Diehl, Christopher M, Parker, Amelia L, Krausz, Kristopher W, Bowman, Elise D, Rabibhadana, Siritida, Forgues, Marshonna, Bhudhisawasdi, Vajarabhongsa, Gonzalez, Frank J, Mahidol, Chulabhorn, Budhu, Anuradha, Wang, Xin W, Ruchirawat, Mathuros, Harris, Curtis C

“…Liver cancer is the second leading cause of cancer-related deaths worldwide. With a predicted 2.4-fold rise in liver cancer incidence by 2020, there is an…”
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Genome-wide profiling of transcription factor activity in primary liver cancer using single-cell ATAC sequencing by Craig, Amanda J., Silveira, Maruhen A. Datsch, Ma, Lichun, Revsine, Mahler, Wang, Limin, Heinrich, Sophia, Rae, Zachary, Ruchinskas, Allison, Dadkhah, Kimia, Do, Whitney, Behrens, Shay, Mehrabadi, Farid R., Dominguez, Dana A., Forgues, Marshonna, Budhu, Anuradha, Chaisaingmongkol, Jittiporn, Hernandez, Jonathan M., Davis, Jeremy L., Tran, Bao, Marquardt, Jens U., Ruchirawat, Mathuros, Kelly, Michael, Greten, Tim F., Wang, Xin W.

“…Primary liver cancer (PLC) consists of two main histological subtypes; hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). The role of…”
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Use of a Cytokine Gene Expression Signature in Lung Adenocarcinoma and the Surrounding Tissue as a Prognostic Classifier by Seike, Masahiro, Yanaihara, Nozomu, Bowman, Elise D., Zanetti, Krista A., Budhu, Anuradha, Kumamoto, Kensuke, Mechanic, Leah E., Matsumoto, Shingo, Yokota, Jun, Shibata, Tatsuhiro, Sugimura, Haruhiko, Gemma, Akihiko, Kudoh, Shoji, Wang, Xin W., Harris, Curtis C.

“…Background A 17-cytokine gene expression signature in noncancerous hepatic tissue from patients with metastatic hepatocellular carcinoma (HCC) was recently…”
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Current concepts of immune based treatments for patients with HCC: from basic science to novel treatment approaches by Greten, Tim F, Wang, Xin W, Korangy, Firouzeh

“…The recent approval of two immune checkpoint inhibitors for the treatment of malignant melanoma has sparked great interest by physicians and basic scientists…”
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Immunology and immunotherapy of cholangiocarcinoma by Greten, Tim F., Schwabe, Robert, Bardeesy, Nabeel, Ma, Lichun, Goyal, Lipika, Kelley, Robin K., Wang, Xin W.

“…Cholangiocarcinoma is the second most common primary liver cancer. Its incidence is low in the Western world but is rising globally. Surgery, chemotherapy and…”
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Understanding tumour cell heterogeneity and its implication for immunotherapy in liver cancer using single-cell analysis by Heinrich, Sophia, Craig, Amanda J., Ma, Lichun, Heinrich, Bernd, Greten, Tim F., Wang, Xin W.

“…Over the last decade, precision medicine and immunotherapeutic approaches have become increasingly popular in oncology. Early clinical trials reported…”
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Biomarkers for immunotherapy of hepatocellular carcinoma by Greten, Tim F., Villanueva, Augusto, Korangy, Firouzeh, Ruf, Benjamin, Yarchoan, Mark, Ma, Lichun, Ruppin, Eytan, Wang, Xin W.

“…Immune-checkpoint inhibitors (ICIs) are now widely used for the treatment of patients with advanced-stage hepatocellular carcinoma (HCC). Two different…”
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MiR‐125b Loss Activated HIF1α/pAKT Loop, Leading to Transarterial Chemoembolization Resistance in Hepatocellular Carcinoma by Wei, Xiyang, Zhao, Lei, Ren, Ruizhe, Ji, Fubo, Xue, Shuting, Zhang, Jianjuan, Liu, Zhaogang, Ma, Zhao, Wang, Xin W., Wong, Linda, Liu, Niya, Shi, Jiong, Guo, Xing, Roessler, Stephanie, Zheng, Xin, Ji, Junfang

“…Background and Aims Transarterial chemoembolization (TACE) is a standard locoregional therapy for patients with hepatocellular carcinoma (HCC) patients with a…”
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Involvement of Crm1 in Hepatitis B Virus X Protein-Induced Aberrant Centriole Replication and Abnormal Mitotic Spindles by Forgues, Marshonna, Difilippantonio, Michael J., Linke, Steven P., Ried, Thomas, Nagashima, Kunio, Feden, Jeffrey, Valerie, Kristoffer, Fukasawa, Kenji, Wang, Xin W.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The p53 tumor suppressor network is a key responder to microenvironmental components of chronic inflammatory stress by STAIB, Frank, ROBLES, Ana I, GALLE, Peter R, HARRIS, Curtis C, VARTICOVSKI, Lyuba, WANG, Xin W, ZEEBERG, Barry R, SIROTIN, Michail, ZHURKIN, Victor B, HOFSETH, Lorne J, HUSSAIN, S. Perwez, WEINSTEIN, John N

“…Activation of the p53 network plays a central role in the inflammatory stress response associated with ulcerative colitis and may modulate cancer risk in…”
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Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma by Chaisaingmongkol, Jittiporn, Budhu, Anuradha, Dang, Hien, Rabibhadana, Siritida, Pupacdi, Benjarath, Kwon, So Mee, Forgues, Marshonna, Pomyen, Yotsawat, Bhudhisawasdi, Vajarabhongsa, Lertprasertsuke, Nirush, Chotirosniramit, Anon, Pairojkul, Chawalit, Auewarakul, Chirayu U., Sricharunrat, Thaniya, Phornphutkul, Kannika, Sangrajrang, Suleeporn, Cam, Maggie, He, Ping, Hewitt, Stephen M., Ylaya, Kris, Wu, Xiaolin, Andersen, Jesper B., Thorgeirsson, Snorri S., Waterfall, Joshua J., Zhu, Yuelin J., Walling, Jennifer, Stevenson, Holly S., Edelman, Daniel, Meltzer, Paul S., Loffredo, Christopher A., Hama, Natsuko, Shibata, Tatsuhiro, Wiltrout, Robert H., Harris, Curtis C., Mahidol, Chulabhorn, Ruchirawat, Mathuros, Wang, Xin W.

“…Intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC) are clinically disparate primary liver cancers with etiological and biological…”
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Loading and Unloading: Orchestrating Centrosome Duplication and Spindle Assembly by Ran/Crm1 by Budhu, Anuradha S., Wang, Xin W.

“…The cell cycle is an intricate process of DNA replication and cell division thatconcludes with the formation of two genetically equivalent daughter cells. In…”
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Hepatitis B Virus X Protein and p53 Tumor Suppressor Interactions in the Modulation of Apoptosis by Elmore, L W, Hancock, A R, Chang, S F, Wang, X W, Chang, S, Callahan, C P, Geller, D A, Will, H, Harris, C C

“…We have reported previously that the hepatitis B virus oncoprotein, HBx, can bind to the C terminus of p53 and inhibit several critical p53-mediated cellular…”
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