Search Results - "Wang, WeiHeng"
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Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-2014)“…siRNA therapeutics have promise for the treatment of a wide range of genetic disorders. Motivated by lipoproteins, we report lipopeptide nanoparticles as…”
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Standalone oblique lateral interbody fusion vs. combined with percutaneous pedicle screw in spondylolisthesis
Published in BMC musculoskeletal disorders (23-03-2020)“…To compare standalone oblique lateral interbody fusion (OLIF) vs. OLIF combined with posterior bilateral percutaneous pedicle screw fixation (OLIF combined)…”
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Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo
Published in Nano letters (10-02-2016)“…Safe and effective delivery is required for siRNA and mRNA-based therapeutics to reach their potential. Here, we report on the development of…”
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Quantitative analysis of paraspinal muscle atrophy after oblique lateral interbody fusion alone vs. combined with percutaneous pedicle screw fixation in patients with spondylolisthesis
Published in BMC musculoskeletal disorders (14-01-2020)“…There is no available literature for comparison on muscle atrophy between the "stand-alone" oblique lateral interbody fusion (OLIF) and regular OLIF (i.e.,…”
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Preliminary studies on the anti-osteoporosis activity of Baohuoside I
Published in Biomedicine & pharmacotherapy (01-07-2019)“…[Display omitted] •Baohuoside I could stimulate BMSCs differentiation into osteoblasts.•Baohuoside I could inhibit BMSCs differentiation into…”
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Frequency Compensation with Capacitor Multiplier in DC–DC Converter
Published in Sensors and materials (05-10-2022)“…In this paper, we present on-chip frequency compensation with a capacitor multiplier for a current-mode control DC–DC converter. The capacitor multiplier…”
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Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymer
Published in Nature biomedical engineering (01-12-2018)“…Continuous glucose monitors (CGMs), used by patients with diabetes mellitus, can autonomously track fluctuations in blood glucose over time. However, the…”
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Alendronate modified mPEG-PLGA nano-micelle drug delivery system loaded with astragaloside has anti-osteoporotic effect in rats
Published in Drug delivery (31-12-2022)“…Astragaloside (AS) has an anti-osteoporotic effect, but its poor water solubility and low bioavailability limit its application. In this study, a novel…”
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Risk factors associated with the prevalence of neck and shoulder pain among high school students: a cross-sectional survey in China
Published in BMC musculoskeletal disorders (09-08-2023)“…After the COVID-19 outbreak, many Chinese high school students have increased their dependence on electronic devices for studying and life, which may affect…”
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Advances of Naturally Derived and Synthetic Hydrogels for Intervertebral Disk Regeneration
Published in Frontiers in bioengineering and biotechnology (30-06-2020)“…Intervertebral disk (IVD) degeneration is associated with most cases of cervical and lumbar spine pathologies, amongst which chronic low back pain has become…”
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Expanding the "Magic Triangle" of Reinforced Rubber Using a Supramolecular Filler Strategy
Published in Materials (27-04-2023)“…A strategy for optimizing the rolling resistance, wet skid and cut resistance of reinforced rubber simultaneously using a supramolecular filler is…”
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Diagnosis and treatment of left ureteral injury as a rare complication of oblique lumbar interbody fusion surgery: a case report and literature review
Published in BMC urology (08-09-2022)“…Background Oblique lumbar interbody fusion (OLIF) surgery has been performed as a minimally invasive lateral lumbar fusion technique in recent years. Reports…”
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13
Hydrogen Promotes the Effectiveness of Bone Mesenchymal Stem Cell Transplantation in Rats with Spinal Cord Injury
Published in Stem cells international (04-05-2023)“…Although bone mesenchymal stem cell (BMSC) transplantation has been applied to the treatment of spinal cord injury (SCI), the effect is unsatisfactory due to…”
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Alendronate-functionalized double network hydrogel scaffolds for effective osteogenesis
Published in Frontiers in chemistry (17-08-2022)“…Development of artificial bone substitutes mimicking the extracellular matrix is a promising strategy for bone repair and regeneration. In views of the actual…”
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Genipin Cross-Linked Decellularized Nucleus Pulposus Hydrogel-Like Cell Delivery System Induces Differentiation of ADSCs and Retards Intervertebral Disc Degeneration
Published in Frontiers in bioengineering and biotechnology (23-12-2021)“…Intervertebral disc degeneration (IDD) is the pathological basis of disc degenerative diseases (DDD). Reduction in the number of cells and degeneration of the…”
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Fabrication of Naturally Derived Double-Network Hydrogels With a Sustained Aspirin Release System for Facilitating Bone Regeneration
Published in Frontiers in chemistry (28-03-2022)“…Continuous efforts on pursuit of effective drug delivery systems for engineering hydrogel scaffolds is considered a promising strategy for the bone-related…”
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Hypoxia regulates adipose mesenchymal stem cells proliferation, migration, and nucleus pulposus-like differentiation by regulating endoplasmic reticulum stress via the HIF-1α pathway
Published in Journal of orthopaedic surgery and research (08-05-2023)“…Hypoxia can promote stem cell proliferation and migration through HIF-1α. Hypoxia can regulate cellular endoplasmic reticulum (ER) stress. Some studies have…”
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Transplantation of Hypoxic-Preconditioned Bone Mesenchymal Stem Cells Retards Intervertebral Disc Degeneration via Enhancing Implanted Cell Survival and Migration in Rats
Published in Stem cells international (01-01-2018)“…Objective. Special hypoxic and hypertonic microenvironment in intervertebral discs (IVDs) decreases the treatment effect of cell transplantation. We…”
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Research of the adaptive control on modulation factor for PSR fly‐back PSM converter
Published in ETRI journal (01-02-2019)“…The energy balance (EB) model of a primary side regulation (PSR) fly‐back converter in the discontinuous conduction mode (DCM) is discussed in this paper…”
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Exosomes from M2c macrophages alleviate intervertebral disc degeneration by promoting synthesis of the extracellular matrix via MiR-124/CILP/TGF-β
Published in Bioengineering & translational medicine (01-11-2023)“…Immuno-inflammation is highly associated with anabolic and catabolic dysregulation of the extracellular matrix (ECM) in the nucleus pulposus (NP), which…”
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