Search Results - "Wang, Victor G"

Whole-exome sequencing capture kit biases yield false negative mutation calls in TCGA cohorts by Wang, Victor G, Kim, Hyunsoo, Chuang, Jeffrey H

“…The Cancer Genome Atlas (TCGA) provides a genetic characterization of more than ten thousand tumors, enabling the discovery of novel driver mutations,…”
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Computational immune synapse analysis reveals T-cell interactions in distinct tumor microenvironments by Wang, Victor G., Liu, Zichao, Martinek, Jan, Foroughi pour, Ali, Zhou, Jie, Boruchov, Hannah, Ray, Kelly, Palucka, Karolina, Chuang, Jeffrey H.

“…The tumor microenvironment (TME) and the cellular interactions within it can be critical to tumor progression and treatment response. Although technologies to…”
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Papillary thyroid cancer immune phenotypes via tumor-infiltrating lymphocyte spatial analysis by Nam, Myungwoo, Yang, Woojung, Kim, Hye Sung, Park, Jewel, Park, Gahee, Kim, Sukjun, Song, Sanghoon, Ock, Chan-Young, Wang, Victor G, Chuang, Jeffrey H, Chae, Young Kwang

“…Standard-of-care treatment options provide an excellent prognosis for papillary thyroid cancers (PTCs); however, approximately 10% of cases are advanced PTCs,…”
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Human KIT+ myeloid cells facilitate visceral metastasis by melanoma by Yu, Chun I, Martinek, Jan, Wu, Te-Chia, Kim, Kyung In, George, Joshy, Ahmadzadeh, Elaheh, Maser, Rick, Marches, Florentina, Metang, Patrick, Authie, Pierre, Oliveira, Vanessa K P, Wang, Victor G, Chuang, Jeffrey H, Robson, Paul, Banchereau, Jacques, Palucka, Karolina

“…Metastasis of melanoma significantly worsens prognosis; thus, therapeutic interventions that prevent metastasis could improve patient outcomes. Here, we show…”
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Transcriptional profiling of macrophages in situ in metastatic melanoma reveals localization-dependent phenotypes and function by Martinek, Jan, Lin, Jianan, Kim, Kyung In, Wang, Victor G., Wu, Te-Chia, Chiorazzi, Michael, Boruchov, Hannah, Gulati, Ananya, Seeniraj, Shamreethaa, Sun, Lili, Marches, Florentina, Robson, Paul, Rongvaux, Anthony, Flavell, Richard A., George, Joshy, Chuang, Jeffrey H., Banchereau, Jacques, Palucka, Karolina

“…Modulation of immune function at the tumor site could improve patient outcomes. Here, we analyze patient samples of metastatic melanoma, a tumor responsive to…”
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Abstract 2832: Multiplex fluorescent imaging of the metastatic melanoma microenvironment reveals spatially-dependent macrophage interactions modulating tumor-infiltrating T-cells by Wang, Victor G., Martinek, Jan, Gulati, Ananya, Boruchov, Hannah, Ray, Kelly, Palucka, Karolina, Chuang, Jeffrey H.

“…Abstract Tumor-infiltrating lymphocytes (TIL) hold strong prognostic value in determining patient survival as well as response to immune checkpoint blockade…”
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Abstract 1750: Human KIT +myeloid cells facilitate visceral organ colonization by melanoma by Yu, Chun I., Martinek, Jan, Wu, Te-Chia, Kim, Kyung In, George, Joshy, Ahmadzadeh, Elaheh, Maser, Rick, Marches, Florentina, Metang, Patrick, Authie, Pierre, Oliveira, Vanessa K., Wang, Victor G., Chuang, Jeffrey H., Robson, Paul, Banchereau, Jacques, Palucka, Karolina

“…Abstract Metastasis is a major risk factor for poor melanoma outcome, but mechanisms supporting distant organ colonization by melanoma are not fully…”
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Abstract 5883: Computational analysis of immune synapses in melanoma tumor microenvironment by Liu, Zichao, Wang, Victor G., Martinek, Jan, Foroughi pour, Ali, Zhou, Jie, Palucka, Karolina, Chuang, Jeffrey H.

“…Abstract High-resolution multiplexed tissue imaging such as imaging mass cytometry (IMC) has enabled quantitative cell characterization with preserved tissue…”
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