Search Results - "Wang, Steven W"

Adenosine and dopamine receptors coregulate photoreceptor coupling via gap junction phosphorylation in mouse retina by Li, Hongyan, Zhang, Zhijing, Blackburn, Michael R, Wang, Steven W, Ribelayga, Christophe P, O'Brien, John

“…Gap junctions in retinal photoreceptors suppress voltage noise and facilitate input of rod signals into the cone pathway during mesopic vision. These synapses…”
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Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis by Kiyama, Takae, Chen, Ching-Kang, Wang, Steven W, Pan, Ping, Ju, Zhenlin, Wang, Jing, Takada, Shinako, Klein, William H, Mao, Chai-An

“…Mitochondrial dysfunction has been implicated in the pathologies of a number of retinal degenerative diseases in both the outer and inner retina. In the outer…”
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Near complete loss of retinal ganglion cells in the math5/brn3b double knockout elicits severe reductions of other cell types during retinal development by Moshiri, Ala, Gonzalez, Ernesto, Tagawa, Kunifumi, Maeda, Hidetaka, Wang, Minhua, Frishman, Laura J., Wang, Steven W.

“…Retinal ganglion cells (RGCs) are the first cell type to differentiate during retinal histogenesis. It has been postulated that specified RGCs subsequently…”
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Birth of cone bipolar cells, but not rod bipolar cells, is associated with existing RGCs by Bai, Ling, Kiyama, Takae, Li, Hongyan, Wang, Steven W

“…Retinal ganglion cells (RGCs) play important roles in retinogenesis. They are required for normal retinal histogenesis and retinal cell number balance…”
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Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5 by Mao, Chai-An, Wang, Steven W, Pan, Ping, Klein, William H

“…Retinal progenitor cells (RPCs) express basic helix-loop-helix (bHLH) factors in a strikingly mosaic spatiotemporal pattern, which is thought to contribute to…”
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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy by Fang, Yong, McGrail, Daniel J, Sun, Chaoyang, Labrie, Marilyne, Chen, Xiaohua, Zhang, Dong, Ju, Zhenlin, Vellano, Christopher P, Lu, Yiling, Li, Yongsheng, Jeong, Kang Jin, Ding, Zhiyong, Liang, Jiyong, Wang, Steven W, Dai, Hui, Lee, Sanghoon, Sahni, Nidhi, Mercado-Uribe, Imelda, Kim, Tae-Beom, Chen, Ken, Lin, Shiaw-Yih, Peng, Guang, Westin, Shannon N, Liu, Jinsong, O'Connor, Mark J, Yap, Timothy A, Mills, Gordon B

“…We demonstrate that concurrent administration of poly(ADP-ribose) polymerase (PARP) and WEE1 inhibitors is effective in inhibiting tumor growth but poorly…”
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Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth by Wang, Steven W, Mu, Xiuqian, Bowers, William J, Kim, Dong-Seob, Plas, Daniel J, Crair, Michael C, Federoff, Howard J, Gan, Lin, Klein, William H

“…In mice, Brn3 POU domain transcription factors play essential roles in the differentiation and survival of projection neurons within the retina, inner ear,…”
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T-box transcription regulator Tbr2 is essential for the formation and maintenance of Opn4/melanopsin-expressing intrinsically photosensitive retinal ganglion cells by Mao, Chai-An, Li, Hongyan, Zhang, Zhijing, Kiyama, Takae, Panda, Satchidananda, Hattar, Samer, Ribelayga, Christophe P, Mills, Stephen L, Wang, Steven W

“…Opsin 4 (Opn4)/melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) play a major role in non-image-forming visual system…”
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Dot1a contains three nuclear localization signals and regulates the epithelial Na+ channel (ENaC) at multiple levels by Reisenauer, Mary Rose, Wang, Steven W, Xia, Yang, Zhang, Wenzheng

“…We have previously reported that Dot1a is located in the cytoplasm and nucleus (Reisenauer MR, Anderson M, Huang L, Zhang Z, Zhou Q, Kone BC, Morris AP, Lesage…”
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Retinal Ganglion Cell Type, Size, and Spacing Can Be Specified Independent of Homotypic Dendritic Contacts by Lin, Bin, Wang, Steven W, Masland, Richard H

“…In Brn3b −/− mice, where 80% of retinal ganglion cells degenerate early in development, the remaining 20% include most or all ganglion cell types. Cells of the…”
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Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development by Mao, Chai-An, Agca, Cavit, Mocko-Strand, Julie A., Wang, Jing, Ullrich-Lüter, Esther, Pan, Ping, Wang, Steven W., Arnone, Maria Ina, Frishman, Laura J., Klein, William H.

“…Pou domain transcription factor Pou4f2 is essential for the development of retinal ganglion cells (RGCs) in the vertebrate retina. A distant orthologue of…”
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Distinct neurogenic potential in the retinal margin and the pars plana of mammalian eye by Kiyama, Takae, Li, Hongyan, Gupta, Manu, Lin, Ya-Ping, Chuang, Alice Z, Otteson, Deborah C, Wang, Steven W

“…Unlike many other vertebrates, a healthy mammalian retina does not grow throughout life and lacks a ciliary margin zone capable of actively generating new…”
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Requirement for math5 in the development of retinal ganglion cells by Wang, S W, Kim, B S, Ding, K, Wang, H, Sun, D, Johnson, R L, Klein, W H, Gan, L

“…math5 is a murine orthologue of atonal, a bHLH proneural gene essential for the formation of photoreceptors and chordotonal organs in Drosophila. The…”
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Retinal ganglion cell death and optic nerve degeneration by genetic ablation in adult mice by Cho, Jang-Hyeon, Mu, Xiuqian, Wang, Steven W., Klein, William H.

“…Despite the magnitude of the problem, no effective treatments exist to prevent retinal ganglion cell (RGC) death and optic nerve degeneration from occurring in…”
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Regulation of Retinal Cone Bipolar Cell Differentiation and Photopic Vision by the CVC Homeobox Gene Vsx1 by Ohtoshi, Akihira, Wang, Steven W, Maeda, Hidetaka, Saszik, Shannon M, Frishman, Laura J, Klein, William H, Behringer, Richard R

“…Cone bipolar cells of the vertebrate retina connect photoreceptors with ganglion cells to mediate photopic vision. Despite this important role, the mechanisms…”
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Mesendoderm cells induce oriented cell division and invagination in the marine shrimp Sicyonia ingentis by Wang, Steven W., Hertzler, Philip L., Clark, Wallis H.

“…The mesendoderm (ME) cells are the two most vegetal blastomeres in the early developing embryo of the marine shrimp Sicyonia ingentis. These two cells enter…”
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Gene expression in the developing mouse retina by EST sequencing and microarray analysis by Mu, X, Zhao, S, Pershad, R, Hsieh, T F, Scarpa, A, Wang, S W, White, R A, Beremand, P D, Thomas, T L, Gan, L, Klein, W H

“…Retinal development occurs in mice between embryonic day E11.5 and post-natal day P8 as uncommitted neuroblasts assume retinal cell fates. The genetic pathways…”
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Abnormal Polarization and Axon Outgrowth in Retinal Ganglion Cells Lacking the POU-Domain Transcription Factor Brn-3b by Wang, Steven W., Gan, Lin, Martin, Suzanna E., Klein, William H.

“…The POU domain transcription factor Brn-3b (also called Brn-3.2) is essential for the normal development of retinal ganglion cells (RGCs) in the mouse. Without…”
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Retinal ganglion cell differentiation in cultured mouse retinal explants by Wang, Steven W., Mu, Xiuqian, Bowers, William J., Klein, William H.

“…The availability of genetically engineered mice harboring specific mutations in genes affecting one or more retinal cell types affords new opportunities for…”
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Should Oral and Maxillofacial Surgeons Routinely Use Disposable Luer-Lock Plastic Syringes Over Stainless-Steel Harpoon Syringes for Third Molar Surgery? by Li, Alexander Y., Wang, Steven W., Ford, Brian P.

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