Search Results - "Wang, Shuiliang"
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Mesenchymal stem cell-derived exosomes protect beta cells against hypoxia-induced apoptosis via miR-21 by alleviating ER stress and inhibiting p38 MAPK phosphorylation
Published in Stem cell research & therapy (04-03-2020)“…Hypoxia is a major cause of beta cell death and dysfunction after transplantation. The aim of this study was to investigate the effect of exosomes derived from…”
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CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy
Published in PloS one (25-08-2017)“…C/EBP-homologous protein (CHOP) is an important component of the endoplasmic reticulum (ER) stress response. We demonstrated the induction of ER stress in…”
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Heterotrimerization of the Growth Factor Receptors erbB2, erbB3, and Insulin-like Growth Factor-I Receptor in Breast Cancer Cells Resistant to Herceptin
Published in Cancer research (Chicago, Ill.) (01-02-2010)“…Primary and acquired resistance to the breast cancer drug trastuzumab (Herceptin) is a significant clinical problem. Here, we report enhanced activation of…”
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ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma
Published in Journal of translational medicine (24-02-2020)“…Clear cell renal cell carcinoma (ccRCC) is a malignancy characterized by metabolic reprogramming. ABAT and ALDH6A1 are metabolic enzymes. In this study, we aim…”
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Screening and Application of DNA Aptamers for Heparin-Binding Protein
Published in Molecules (Basel, Switzerland) (01-04-2024)“…Rapid detection of heparin-binding protein (HBP) is essential for timely intervention in sepsis cases. Current detection techniques are usually antibody-based…”
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Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers
Published in Cell cycle (Georgetown, Tex.) (15-01-2012)“…A distinct group of breast cancers, called "basal" or "triple-negative" (TN) cancers express both basal cytokeratins and the epidermal growth factor receptor,…”
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Role of Exosomes in Cancer and Aptamer-Modified Exosomes as a Promising Platform for Cancer Targeted Therapy
Published in Biological procedures online (27-05-2024)“…Exosomes are increasingly recognized as important mediators of intercellular communication in cancer biology. Exosomes can be derived from cancer cells as well…”
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Functional Long Noncoding RNAs (lncRNAs) in Clear Cell Kidney Carcinoma Revealed by Reconstruction and Comprehensive Analysis of the lncRNA-miRNA-mRNA Regulatory Network
Published in Medical science monitor (16-11-2018)“…BACKGROUND A variety of treatment strategies have been developed for clear cell kidney carcinoma (KIRC); however, there is still a need for effective…”
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MiR-30a-5p frequently downregulated in prostate cancer inhibits cell proliferation via targeting PCLAF
Published in Artificial cells, nanomedicine, and biotechnology (01-12-2019)“…MicroRNAs (miRNAs) have vastly expanded our view of RNA world in intracellular signal regulating networks. Here, we functionally characterized a normally…”
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Determination of ultra-trace organic acids in Masson pine (Pinus massoniana L.) by accelerated solvent extraction and liquid chromatography–tandem mass spectrometry
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-02-2015)“…•An LC–MS/MS method for the determination of organic acids in P. massoniana.•P. massoniana was pretreated with ASE/SPE and analyzed by LC–MS/MS.•Parameters…”
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Valproic acid exhibits anti-tumor activity selectively against EGFR/ErbB2/ErbB3-coexpressing pancreatic cancer via induction of ErbB family members-targeting microRNAs
Published in Journal of experimental & clinical cancer research (08-04-2019)“…Deregulated ErbB signaling plays an important role in tumorigenesis of pancreatic cancer. However, patients with pancreatic cancer benefit little from current…”
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Dichloromethane as a methylene synthon for regioselective linkage of diverse carboxylic acids: Direct access to methylene diesters under metal-free conditions
Published in Chinese chemical letters (01-06-2019)“…This simple protocol is a convenient and cost-effective route to synthesize methylene diesters from a wide scope of carboxylic acids substrates with good…”
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HDAC inhibitor SNDX-275 induces apoptosis in erbB2-overexpressing breast cancer cells via down-regulation of erbB3 expression
Published in Cancer research (Chicago, Ill.) (01-11-2009)“…Breast cancer is a highly heterogeneous disease with distinct histologic subtypes. Targeted therapies such as endocrine therapy and growth factor receptor…”
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Knockdown of CYP24A1 Aggravates 1α,25(OH)2D3-Inhibited Migration and Invasion of Mouse Ovarian Epithelial Cells by Suppressing EMT
Published in Frontiers in oncology (29-07-2020)“…Epithelial-mesenchymal transition (EMT) bestows cancer cells with motile and invasive properties. But for ovarian tissues, EMT plays a physiological role in…”
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Combination of bendamustine and entinostat synergistically inhibits proliferation of multiple myeloma cells via induction of apoptosis and DNA damage response
Published in Cancer letters (28-07-2013)“…Highlights ► Synergy of entinostat and bendamustine. ► Apoptosis and DNA damage. ► Novel therapy for MM…”
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Prognostic values of GMPS, PR, CD40, and p21 in ovarian cancer
Published in PeerJ (San Francisco, CA) (25-01-2019)“…Early detection and prediction of prognosis and treatment responses are all the keys in improving survival of ovarian cancer patients. This study profiled an…”
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Phytoavailability and speciation of aluminum carried by total suspended particulates (TSP) to Masson pine ( Pinus massoniana L.)
Published in Atmospheric environment (1994) (01-02-2012)“…Aluminum (Al) is an abundant metal in airborne particulate matter. Al concentrations carried by total suspended particulates (TSP) of the Nanjing atmosphere…”
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Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma
Published in BMC cancer (16-06-2011)“…Cladribine or 2-chlorodeoxyadenosine (2-CDA) is a well-known purine nucleoside analog with particular activity against lymphoproliferative disorders, such as…”
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The zinc finger transcription factor 191 is required for early embryonic development and cell proliferation
Published in Experimental cell research (10-12-2006)“…Human zinc finger protein 191 (ZNF191/ZNF24) was cloned and characterized as a SCAN family member, which shows 94% identity to its mouse homologue zinc finger…”
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