Search Results - "Wang, Sheau Pey"

Activation of Syk in Peripheral Blood B Cells in Patients With Rheumatoid Arthritis: A Potential Target for Abatacept Therapy by Iwata, Shigeru, Nakayamada, Shingo, Fukuyo, Shunsuke, Kubo, Satoshi, Yunoue, Naoki, Wang, Sheau‐Pey, Yoshikawa, Maiko, Saito, Kazuyoshi, Tanaka, Yoshiya

“…Objective B cells play a pivotal role in the pathogenesis of autoimmune diseases. Although Syk functions as a key molecule in B cell receptor signaling, the…”
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Tofacitinib, a JAK inhibitor, inhibits human B cell activation in vitro by Wang, Sheau-Pey, Iwata, Shigeru, Nakayamada, Shingo, Sakata, Kei, Yamaoka, Kunihiro, Tanaka, Yoshiya

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Amplification of Toll-like receptor–mediated signaling through spleen tyrosine kinase in human B-cell activation by Iwata, Shigeru, MD, PhD, Yamaoka, Kunihiro, MD, PhD, Niiro, Hiroaki, MD, PhD, Nakano, Kazuhisa, MD, PhD, Wang, Sheau-Pey, MS, Akashi, Koichi, MD, PhD, Tanaka, Yoshiya, MD, PhD

“…Background B cells are activated by combined signals through the B-cell receptor (BCR) and CD40. However, the underlying mechanisms by which BCR signals…”
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Amplification of IL-21 signalling pathway through Bruton's tyrosine kinase in human B cell activation by Wang, Sheau-Pey, Iwata, Shigeru, Nakayamada, Shingo, Niiro, Hiroaki, Jabbarzadeh-Tabrizi, Siamak, Kondo, Masahiro, Kubo, Satoshi, Yoshikawa, Maiko, Tanaka, Yoshiya

“…B cells play an important role in the pathogenesis of autoimmune diseases. The role of Bruton's tyrosine kinase (Btk) in cytokine-induced human B cell…”
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Abnormal expression of chemokine receptor on B cells in patients with SLE by Yoshikawa, Maiko, Nakayamada, Shingo, Iwata, Shigeru, Kubo, Satoshi, Yunoue, Naoki, Wang, Sheau-Pey, Tanaka, Yoshiya

“…SLE is a systemic autoimmune disease characterized by overactivation of autoreactive memory B cells. However, little is known about the mechanism of…”
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Involvement of Syk in pathology of systemic autoimmune disease by Iwata, Shigeru, Yamaoka, Kunihiro, Niiro, Hiroaki, Nakano, Kazuhisa, Wang, Sheau-Pey, Saito, Kazuyoshi, Akashi, Koichi, Tanaka, Yoshiya

“…Biological products have proven its high efficacy on autoimmune disease such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Meanwhile,…”
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Type I and II interferons commit to abnormal expression of chemokine receptor on B cells in patients with systemic lupus erythematosus by Yoshikawa, Maiko, Nakayamada, Shingo, Kubo, Satoshi, Nawata, Aya, Kitanaga, Yukihiro, Iwata, Shigeru, Sakata, Kei, Ma, Xiaoxue, Wang, Sheau Pey, Nakano, Kazuhisa, Saito, Kazuyoshi, Tanaka, Yoshiya

“…Memory B cells are increased in systemic lupus erythematosus (SLE) cases, but the qualitative abnormalities and induction mechanism of these cells are unclear…”
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Amplification of Toll-like receptoramediated signaling through spleen tyrosine kinase in human B-cell activation by Iwata, Shigeru, Yamaoka, Kunihiro, Niiro, Hiroaki, Nakano, Kazuhisa, Wang, Sheau-Pey, Akashi, Koichi, Tanaka, Yoshiya

“…Background: B cells are activated by combined signals through the B-cell receptor (BCR) and CD40. However, the underlying mechanisms by which BCR signals…”
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