Search Results - "Wang, Shanglong"
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Acute, subchronic toxicity and genotoxicity studies of JointAlive, a traditional Chinese medicine formulation for knee osteoarthritis
Published in PloS one (17-10-2023)“…Aim In vivo and in vitro toxicity tests of JointAlive.sup.® were studied in animal models to support the safe use of JointAlive.sup.® as a drug for knee…”
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Bacillus natto regulates gut microbiota and adipose tissue accumulation in a high-fat diet mouse model of obesity
Published in Journal of functional foods (01-05-2020)“…[Display omitted] •The direct anti-obesity of Bacillus natto is investigated for the first time.•The mechanism of B. natto regulating metabolic disorders was…”
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The antihypertensive effect and mechanisms of bioactive peptides from Ruditapes philippinarum fermented with Bacillus natto in spontaneously hypertensive rats
Published in Journal of functional foods (01-04-2021)“…[Display omitted] •Oral administration of RBPs reduced blood pressures in SHRs.•RBPs improved the injuries of kidney, blood vessel and heart in SHRs.•RBPs…”
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The Ameliorative Effect and Mechanisms of Ruditapes philippinarum Bioactive Peptides on Obesity and Hyperlipidemia Induced by a High-Fat Diet in Mice
Published in Nutrients (28-11-2022)“…In this study, bioactive peptides (RBPs) from were prepared by fermentation with and the effect and mechanisms of RBPs on obesity and hyperlipidemia were…”
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Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer's Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway
Published in Frontiers in pharmacology (28-02-2022)“…Alzheimer's disease (AD) as an age-related, irreversible neurodegenerative disease, characterized by cognitive dysfunction, has become progressively serious…”
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Positive Effect of a Pea-Clam Two-Peptide Composite on Hypertension and Organ Protection in Spontaneously Hypertensive Rats
Published in Nutrients (30-09-2022)“…In the present study, we prepared pea peptides with high angiotensin-converting enzyme (ACE) inhibitory activity in vitro using an enzymatic hydrolysis of pea…”
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Amelioration of hyperuricemia by Lactobacillus acidophilus F02 with uric acid-lowering ability via modulation of NLRP3 inflammasome and gut microbiota homeostasis
Published in Journal of functional foods (01-12-2023)“…Hyperuricemia is a metabolic disease caused by disturbances in purine metabolism and imbalances in the formation and excretion of uric acid. It is closely…”
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Drug conjugates for the treatment of lung cancer: from drug discovery to clinical practice
Published in Experimental hematology & oncology (01-03-2024)“…A drug conjugate consists of a cytotoxic drug bound via a linker to a targeted ligand, allowing the targeted delivery of the drug to one or more tumor sites…”
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Eucommia, Cuscuta, and Drynaria Extracts Ameliorate Glucocorticoid-Induced Osteoporosis by Inhibiting Osteoclastogenesis Through PI3K/Akt Pathway
Published in Frontiers in pharmacology (04-02-2022)“…Osteoporosis is one of the most common diseases in the world which resulted in heavy socioeconomic burden and a public health threat. Glucocorticoid-induced…”
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Safety evaluation of CuminUP60® – A novel curcumin complex
Published in Toxicology reports (01-01-2022)“…Curcuma longa L. is one of the most recognized Curcuma species (Sharifi-Rad et al., 2020 [3]). Curcumin, the primary polyphenolic compound found in turmeric…”
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Quantitative proteomics reveals the therapeutic effects of RFAP against depression via pathway regulation of long-term depression and potentiation
Published in Heliyon (01-03-2023)“…RFAP is a compound extraction complex of four Traditional Chinese Medicine (TCM), including the dry bark of Paeonia lactiflora Pall. (Radix Paeoniae Alba),…”
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A novel solvent-free co-grinding preparation improves curcumin bioavailability in healthy volunteers: A single-center crossover study
Published in Heliyon (01-01-2023)“…Curcumin, from the rhizome of turmeric (Curcuma longa L.), has a wide variety of biological activities. Unfortunately, its poor water-solubility greatly limits…”
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Emulsified blend film based on konjac glucomannan/carrageenan/ camellia oil: Physical, structural, and water barrier properties
Published in Carbohydrate polymers (01-01-2021)“…[Display omitted] •The addition of camellia oil (CO) improved the physical properties of KGM-KC films.•The hydrophobicity of KGM-KC films was improved due to…”
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Identification and Antihypertension Study of Novel Angiotensin I-Converting Enzyme Inhibitory Peptides from the Skirt of Chlamys farreri Fermented with Bacillus natto
Published in Journal of agricultural and food chemistry (13-01-2021)“…The aim of this study was to isolate the angiotensin I-converting enzyme (ACE) inhibitory peptides from the skirt of fermented with and to explore the…”
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Discovery of non-antiproliferative selective estrogen receptor degraders (SERDs) based on scaffold optimization of elacestrant
Published in European journal of medicinal chemistry (05-12-2024)“…Elacestrant, the first oral selective estrogen receptor degrader (SERD), has been approved for ER positive breast cancer in 2023. Recent study showed that…”
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Positive effect of compound amino acid chelated calcium from the shell and skirt of scallop in an ovariectomized rat model of postmenopausal osteoporosis
Published in Journal of the science of food and agriculture (15-03-2022)“…BACKGROUND Osteoporosis has become an important public health issue with the increase of aging population, and afflicts millions of people worldwide,…”
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Sample regeneration algorithm for structural failure probability function estimation
Published in Probabilistic engineering mechanics (01-01-2023)“…An efficient strategy to approximate the failure probability function in structural reliability problems is proposed. The failure probability function (FPF) is…”
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Antimicrobial and Preservative Effects of the Combinations of Nisin, Tea Polyphenols, Rosemary Extract, and Chitosan on Pasteurized Chicken Sausage
Published in Journal of food protection (01-02-2021)“…This study was conducted to evaluate the antimicrobial and preservative effects of the combinations of nisin (NS), tea polyphenols (TP), rosemary extract (RE),…”
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Effect of high-pressure homogenization on structural changes and emulsifying properties of chicken liver proteins isolated by isoelectric solubilization/precipitation
Published in Food science & technology (01-11-2021)“…This study investigated the effect of high-pressure homogenization (HPH) (0, 20, 40 and 60 MPa) on the emulsifying properties and structural changes of chicken…”
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Sheng Mai yin shows anti-fatigue, anti-hypoxia and cardioprotective potential in an experimental joint model of fatigue and acute myocardial infarction
Published in Journal of ethnopharmacology (30-01-2024)“…Cardiovascular disease (CVD) and fatigue are two common diseases endangering human life and health that may interact and reinforce one another. Myocardial…”
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