Search Results - "Wang, Rongchun"
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Synergistic effects of MFG-E8 and whey protein on mitigating d-galactose-induced sarcopenia through PI3K/AKT/PGC-1α and MAPK/ERK signaling pathways
Published in Journal of dairy science (01-01-2024)“…Milk fat globule epidermal growth factor 8 (MFG-E8) and whey protein have emerged as promising bionutrient supplements for enhancing skeletal muscle mass and…”
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2
DRC1 deficiency caused primary ciliary dyskinesia and MMAF in a Chinese patient
Published in Journal of human genetics (01-04-2022)“…Primary ciliary dyskinesia (PCD) is a heterogeneous disease characterized by the failure of mucociliary clearance. Dynein regulatory complex subunit 1 (DRC1)…”
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3
Whey protein peptides PEW and LLW synergistically ameliorate hyperuricemia and modulate gut microbiota in potassium oxonate and hypoxanthine-induced hyperuricemic rats
Published in Journal of dairy science (01-11-2023)“…PEW and LLW are peptides derived from whey protein digestive products; both peptides exhibit xanthine oxidase inhibitory activity in vitro. However, it remains…”
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In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways
Published in Molecules (Basel, Switzerland) (01-03-2019)“…: Polyphyllin VII (PP7), a steroidal saponin from , has been found to exert strong anticancer activity. Little is known about the anti-inflammatory property of…”
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5
Developmental toxicity induced by PM2.5 through endoplasmic reticulum stress and autophagy pathway in zebrafish embryos
Published in Chemosphere (Oxford) (01-04-2018)“…The aims of this study were to investigate the mechanism underlying the developmental toxicity of fine particulate matter (PM2.5) and provide a more thorough…”
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Synergistic effects of Pb and repeated heat pulse on developmental neurotoxicity in zebrafish
Published in Ecotoxicology and environmental safety (15-05-2019)“…Pollutant discharges to the aquatic environment often contain multiple environmental stressors, affecting aquatic organisms. To mimic the discharges from…”
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Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells
Published in Journal of dairy science (01-04-2023)“…The objective of this study was to investigate the mechanism by which the α-lactalbumin peptides Gly-Ile-Asn-Tyr (GINY) and Asp-Gln-Trp (DQW) ameliorate free…”
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Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish
Published in Antimicrobial agents and chemotherapy (01-05-2019)“…Isoniazid (INH) is a first-line antituberculosis drug. The incidence of adverse reactions accompanied by inflammation in the liver during drug administration…”
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The contribution of Pseudomonas aeruginosa infection to clinical outcomes in bronchiectasis: a prospective cohort study
Published in Annals of medicine (Helsinki) (01-01-2021)“…The impact of Pseudomonas aeruginosa on the prognosis of bronchiectasis remains controversial. This study aimed to explore the prognostic value of P…”
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Peptides released from bovine α-lactalbumin by simulated digestion alleviated free fatty acids-induced lipid accumulation in HepG2 cells
Published in Journal of functional foods (01-10-2021)“…•Peptides from α-LA decreased lipid accumulation in HepG2 cells.•The peptides of P2 (GINY) and P8 (DQW) acted as PPARα ligands.•P2 and P8 up-regulated genes…”
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α-Lactalbumin ameliorates hepatic lipid metabolism in high-fat-diet induced obese C57BL/6J mice
Published in Journal of functional foods (01-12-2020)“…α-Lactalbumin improves high-fat-diet induced obesity and hepatic lipid metabolism by activating fatty acid β-oxidation and inhibiting lipogenesis in the liver…”
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12
Evaluation of the Developmental Toxicity Induced by E804 in Zebrafish Embryos
Published in Frontiers in pharmacology (14-02-2020)“…E804, a derivative of indirubin, have multi-biological activities such as anticancer and anti-inflammatory activities, but little is known about its…”
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Altechromone A Ameliorates Inflammatory Bowel Disease by Inhibiting NF-κB and NLRP3 Pathways
Published in Marine drugs (09-09-2024)“…Altechromone A, also known as 2,5-dimethyl-7-hydroxychromone, is a hydroxyketone containing one hydroxyl and one ketone group. In this study, we isolated…”
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Valorisation of Potato (Solanum tuberosum) Peel Waste: Extraction of Fibre, Monosaccharides and Uronic Acids
Published in Waste and biomass valorization (01-05-2020)“…Purpose The food and starch industries generate large quantities of potato peel waste (PPW) that can be exploited for a range of biotechnological and biofuel…”
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Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification
Published in Molecules (Basel, Switzerland) (01-04-2024)“…Silibinin is a flavonoid compound extracted from the seeds of (L.) Gaertn. It has the functions of liver protection, blood-lipid reduction and anti-tumor…”
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New Prenylated Indole Homodimeric and Pteridine Alkaloids from the Marine-Derived Fungus Aspergillus austroafricanus Y32-2
Published in Marine drugs (09-02-2021)“…Chemical investigation of secondary metabolites from the marine-derived fungus Y32-2 resulted in the isolation of two new prenylated indole alkaloid…”
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Protection of Spleen Tissue of γ-ray Irradiated Mice against Immunosuppressive and Oxidative Effects of Radiation by Adenosine 5'-Monophosphate
Published in International journal of molecular sciences (24-04-2018)“…The immune system is very sensitive to radiation. This study revealed that adenosine 5′-monophosphate (5′-AMP) increased the DNA contents of the spleen and the…”
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Cationic anticancer peptide L-K6-modified and doxorubicin-loaded mesoporous silica nanoparticles reverse multidrug resistance of breast cancer
Published in Arabian journal of chemistry (01-05-2024)“…Multidrug resistance (MDR) is the major challenge for chemotherapy of cancer and makes the treatment benefits unsustainable. To overcome this issue,…”
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Case Report: DNAAF4 Variants Cause Primary Ciliary Dyskinesia and Infertility in Two Han Chinese Families
Published in Frontiers in genetics (12-07-2022)“…Background : Primary ciliary dyskinesia (PCD) is a rare genetic disorder, predominantly autosomal recessive. The dynein axonemal assembly factor 4 ( DNAAF4 )…”
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Novel RSPH4A Variants Associated With Primary Ciliary Dyskinesia-Related Infertility in Three Chinese Families
Published in Frontiers in genetics (22-06-2022)“…The radial spoke head component 4A ( ) is involved in the assembly of radial spokes, which is essential for motile cilia function. Asthenoteratozoospermia in…”
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