Search Results - "Wang, Qing K."

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure by Yao, Yufeng, Lu, Qiulun, Hu, Zhenkun, Yu, Yubin, Chen, Qiuyun, Wang, Qing K.

“…Endoplasmic reticulum stress is an evolutionarily conserved cell stress response associated with numerous diseases, including cardiac hypertrophy and heart…”
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AGGF1 therapy inhibits thoracic aortic aneurysms by enhancing integrin α7-mediated inhibition of TGF-β1 maturation and ERK1/2 signaling by Da, Xingwen, Li, Ziyan, Huang, Xiaofan, He, Zuhan, Yu, Yubing, Tian, Tongtong, Xu, Chengqi, Yao, Yufeng, Wang, Qing K.

“…Thoracic aortic aneurysm (TAA) is a localized or diffuse dilatation of the thoracic aortas, and causes many sudden deaths each year worldwide. However, there…”
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Genome-Wide Analysis of DNA Methylation and Acute Coronary Syndrome by Li, Jun, Zhu, Xiaoyan, Yu, Kuai, Jiang, Haijing, Zhang, Yizhi, Deng, Siyun, Cheng, Longxian, Liu, Xuezhen, Zhong, Jia, Zhang, Xiaomin, He, Meian, Chen, Weihong, Yuan, Jing, Gao, Ming, Bai, Yansen, Han, Xu, Liu, Bing, Luo, Xiaoting, Mei, Wenhua, He, Xiaosheng, Sun, Shunchang, Zhang, Liyun, Zeng, Hesong, Sun, Huizhen, Liu, Chuanyao, Guo, Yanjun, Zhang, Bing, Zhang, Zhihong, Huang, Jinyan, Pan, An, Yuan, Yu, Angileri, Francesca, Ming, Bingxia, Zheng, Fang, Zeng, Qiutang, Mao, Xiaobo, Peng, Yudong, Mao, Yi, He, Ping, Wang, Qing K, Qi, Lu, Hu, Frank B, Liang, Liming, Wu, Tangchun

“…RATIONALE:Acute coronary syndrome (ACS) is a leading cause of death worldwide. Immune functions play a vital role in ACS development, however, whether…”
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TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response by Chen, Jianwen, He, Ruirui, Sun, Wanwei, Gao, Ru, Peng, Qianwen, Zhu, Liwen, Du, Yanyun, Ma, Xiaojian, Guo, Xiaoli, Zhang, Huazhi, Tan, Chengcheng, Wang, Junhan, Zhang, Wei, Weng, Xiufang, Man, Jianghong, Bauer, Hermann, Wang, Qing K., Martin, Bradley N., Zhang, Cun-Jin, Li, Xiaoxia, Wang, Chenhui

“…The TAGAP gene locus has been linked to several infectious diseases or autoimmune diseases, including candidemia and multiple sclerosis. While previous studies…”
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Post-transcriptional regulation of cardiac sodium channel gene SCN5A expression and function by miR-192-5p by Zhao, Yuanyuan, Huang, Yuan, Li, Weihua, Wang, Zhijie, Zhan, Shaopeng, Zhou, Mengchen, Yao, Yufeng, Zeng, Zhipeng, Hou, Yuxi, Chen, Qiuyun, Tu, Xin, Wang, Qing K., Huang, Zhengrong

“…The SCN5A gene encodes cardiac sodium channel Nav1.5 and causes lethal ventricular arrhythmias/sudden death and atrial fibrillation (AF) when mutated…”
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Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation by Huang, Yufeng, Wang, Chuchu, Yao, Yufeng, Zuo, Xiaoyu, Chen, Shanshan, Xu, Chengqi, Zhang, Hongfu, Lu, Qiulun, Chang, Le, Wang, Fan, Wang, Pengxia, Zhang, Rongfeng, Hu, Zhenkun, Song, Qixue, Yang, Xiaowei, Li, Cong, Li, Sisi, Zhao, Yuanyuan, Yang, Qin, Yin, Dan, Wang, Xiaojing, Si, Wenxia, Li, Xiuchun, Xiong, Xin, Wang, Dan, Huang, Yuan, Luo, Chunyan, Li, Jia, Wang, Jingjing, Chen, Jing, Wang, Longfei, Wang, Li, Han, Meng, Ye, Jian, Chen, Feifei, Liu, Jingqiu, Liu, Ying, Wu, Gang, Yang, Bo, Cheng, Xiang, Liao, Yuhua, Wu, Yanxia, Ke, Tie, Chen, Qiuyun, Tu, Xin, Elston, Robert, Rao, Shaoqi, Yang, Yanzong, Xia, Yunlong, Wang, Qing K

“…Atrial fibrillation (AF) is the most common cardiac arrhythmia at the clinic. Recent GWAS identified several variants associated with AF, but they account for…”
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Protein therapy of skeletal muscle atrophy and mechanism by angiogenic factor AGGF1 by He, Zuhan, Song, Qixue, Yu, Yubing, Liu, Feng, Zhao, Jinyan, Un, Waikeong, Da, Xingwen, Xu, Chengqi, Yao, Yufeng, Wang, Qing K.

“…Background Skeletal muscle atrophy is a common condition without a pharmacologic therapy. AGGF1 encodes an angiogenic factor that regulates cell…”
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The IL-33-ST2L Pathway Is Associated with Coronary Artery Disease in a Chinese Han Population by Tu, Xin, Nie, Shaofang, Liao, Yuhua, Zhang, Hongsong, Fan, Qian, Xu, Chengqi, Bai, Ying, Wang, Fan, Ren, Xiang, Tang, Tingting, Xia, Ni, Li, Sisi, Huang, Yuan, Liu, Juan, Yang, Qing, Zhao, Yuanyuan, Lv, Qiulun, Li, Qingxian, Li, Yue, Xia, Yunlong, Qian, Jin, Li, Bin, Wu, Gang, Wu, Yanxia, Yang, Yan, Wang, Qing K., Cheng, Xiang

“…The effects of interleukin-33 (IL-33) on the immune system have been clearly demonstrated; however, in cardiovascular diseases, especially in coronary artery…”
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Genetic susceptibility to myocardial infarction and coronary artery disease by Topol, Eric J., Smith, Jonathan, Plow, Edward F., Wang, Qing K.

“…Atherosclerotic involvement in the coronary arteries, which can result in heart attack and sudden death, is a common disease and prototypic of a complex human…”
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Analysis of causal effect of APOA5 variants on premature coronary artery disease by Wang, Fan, Wang, Isabel Z., Ellis, Stephen, Archacki, Stephen, Barnard, John, Hubbard, Carlos, Topol, Eric J., Chen, Qiuyun, Wang, Qing K.

“…Apolipoprotein A5 (APOA5) regulates the metabolisms of triglyceride and HDL. APOA5 variants have been linked to coronary artery disease (CAD), but their causal…”
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Integrative Analysis of miRNA and mRNA Expression Profiles Associated With Human Atrial Aging by Yao, Yan, Jiang, Chenxi, Wang, Fan, Yan, Han, Long, Deyong, Zhao, Jinghua, Wang, Jiangang, Zhang, Chunxiao, Li, Yang, Tian, Xiaoli, Wang, Qing K, Wu, Gang, Zhang, Zhihui

“…Limited findings have been reported to systematically study miRNA and mRNA expression profiles in aged human atria. In this study, we aimed to identify miRNAs,…”
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Genome-Wide Linkage Analysis of Large Multiple Multigenerational Families Identifies Novel Genetic Loci for Coronary Artery Disease by Guo, Yang, Wang, Fan, Li, Lin, Gao, Hanxiang, Arckacki, Stephen, Wang, Isabel Z., Barnard, John, Ellis, Stephen, Hubbard, Carlos, Topol, Eric J., Chen, Qiuyun, Wang, Qing K.

“…Coronary artery disease (CAD) is the leading cause of death, and genetic factors contribute significantly to risk of CAD. This study aims to identify new CAD…”
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Association of SNP Rs9943582 in APLNR with Left Ventricle Systolic Dysfunction in Patients with Coronary Artery Disease in a Chinese Han GeneID Population by Wang, Pengyun, Xu, Chengqi, Wang, Chuchu, Wu, Yanxia, Wang, Dan, Chen, Shanshan, Zhao, Yuanyuan, Wang, Xiaojing, Li, Sisi, Yang, Qin, Zeng, Qiutang, Tu, Xin, Liao, Yuhua, Wang, Qing K, Cheng, Xiang

“…Heart failure affects 1-2% of the adult population worldwide and coronary artery disease (CAD) is the underlying etiology of heart failure in 70% of the…”
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Association between four SNPs on chromosome 9p21 and myocardial infarction is replicated in an Italian population by Shen, Gong-Qing, Rao, Shaoqi, Martinelli, Nicola, Li, Lin, Olivieri, Oliviero, Corrocher, Roberto, Abdullah, Kalil G, Hazen, Stanley L, Smith, Jonathan, Barnard, John, Plow, Edward F, Girelli, Domenico, Wang, Qing K

“…Genome-wide single nucleotide polymorphism (SNP) association studies recently identified four SNPs (rs10757274, rs2383206, rs2383207, and rs10757278) on…”
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Significant Association Between CAV1 Variant rs3807989 on 7p31 and Atrial Fibrillation in a Chinese Han Population by Chen, Shanshan, Wang, Chuchu, Wang, Xiaojing, Xu, Chengqi, Wu, Manman, Wang, Pengxia, Tu, Xin, Wang, Qing K.

“…Background Recent genome‐wide association studies (GWAS) in European ancestry populations revealed several genomic loci for atrial fibrillation (AF). We…”
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Genetic variants at newly identified lipid loci are associated with coronary heart disease in a Chinese Han population by Zhou, Li, Ding, Hu, Zhang, Xiaomin, He, Meian, Huang, Suli, Xu, Yujun, Shi, Ying, Cui, Guanglin, Cheng, Longxian, Wang, Qing K, Hu, Frank B, Wang, Daowen, Wu, Tangchun

“…Recent genome-wide association studies (GWAS) have mapped several novel loci influencing blood lipid levels in Caucasians. We sought to explore whether the…”
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Identification of a novel genetic locus on chromosome 8p21.1-q11.23 for idiopathic basal ganglia calcification by Dai, Xiaohua, Gao, Yong, Xu, Zhenping, Cui, Xiaoniu, Liu, Juan, Li, Yulei, Xu, Haibo, Liu, Mugen, Wang, Qing K., Liu, Jing Yu

“…Idiopathic basal ganglia calcification (IBGC) is a neurodegenerative disorder that is characterized by basal ganglia and extrabasal ganglia calcification, and…”
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Loss of heterozygosity detected at three short tandem repeat locus commonly used for human DNA identification in a case of paternity testing by Zhou, Shiyuan, Wang, Haili, Wang, Qing K, Wang, Pengyun, Wang, Fengyu, Xu, Chengqi

“…Graphical abstract…”
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Genetic Regulation of the Thymic Stromal Lymphopoietin (TSLP)/TSLP Receptor (TSLPR) Gene Expression and Influence of Epistatic Interactions Between IL-33 and the TSLP/TSLPR Axis on Risk of Coronary Artery Disease by Nie, Shao-Fang, Zha, Ling-Feng, Fan, Qian, Liao, Yu-Hua, Zhang, Hong-Song, Chen, Qian-Wen, Wang, Fan, Tang, Ting-Ting, Xia, Ni, Xu, Cheng-Qi, Zhang, Jiao-Yue, Lu, Yu-Zhi, Zeng, Zhi-Peng, Jiao, Jiao, Li, Yuan-Yuan, Xie, Tian, Zhang, Wen-Juan, Wang, Dan, Wang, Chu-Chu, Fa, Jing-Jing, Xiong, Hong-Bo, Ye, Jian, Yang, Qing, Wang, Peng-Yun, Tian, Sheng-Hua, Lv, Qiu-Lun, Li, Qing-Xian, Qian, Jin, Li, Bin, Wu, Gang, Wu, Yan-Xia, Yang, Yan, Yang, Xiang-Ping, Hu, Yu, Wang, Qing K, Cheng, Xiang, Tu, Xin

“…The thymic stromal lymphopoietin (TSLP)/TSLP receptor (TSLPR) axis is involved in multiple inflammatory immune diseases, including coronary artery disease…”
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Genome-wide linkage scan identifies two novel genetic loci for coronary artery disease: in GeneQuest families by Gao, Hanxiang, Li, Lin, Rao, Shaoqi, Shen, Gongqing, Xi, Quansheng, Chen, Shenghan, Zhang, Zheng, Wang, Kai, Ellis, Stephen G, Chen, Qiuyun, Topol, Eric J, Wang, Qing K

“…Coronary artery disease (CAD) is the leading cause of death worldwide. Recent genome-wide association studies (GWAS) identified >50 common variants associated…”
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