Search Results - "Wang, Qinchuan"

Immune checkpoint-related serum proteins and genetic variants predict outcomes of localized prostate cancer, a cohort study by Wang, Qinchuan, Ye, Yuanqing, Yu, Hao, Lin, Shu-Hong, Tu, Huakang, Liang, Dong, Chang, David W., Huang, Maosheng, Wu, Xifeng

“…Background The clinical predictors and biological mechanisms for localized prostate cancer (PCa) outcomes remain mostly unknown. We aim to evaluate the role of…”
Get full text

Soluble immune checkpoint-related proteins as predictors of tumor recurrence, survival, and T cell phenotypes in clear cell renal cell carcinoma patients by Wang, Qinchuan, Zhang, Jinhua, Tu, Huakang, Liang, Dong, Chang, David. W., Ye, Yuanqing, Wu, Xifeng

“…BackgroundImmune checkpoint inhibitors have achieved unprecedented success in cancer immunotherapy. With the exception of a few candidate biomarkers, the…”
Get full text

CaMKII as a Therapeutic Target in Cardiovascular Disease by Reyes Gaido, Oscar E, Nkashama, Lubika J, Schole, Kate L, Wang, Qinchuan, Umapathi, Priya, Mesubi, Olurotimi O, Konstantinidis, Klitos, Luczak, Elizabeth D, Anderson, Mark E

“…CaMKII (the multifunctional Ca 2+ and calmodulin-dependent protein kinase II) is a highly validated signal for promoting a variety of common diseases,…”
Get full text

Analysis of neoadjuvant chemotherapy for breast cancer: a 20-year retrospective analysis of patients of a single institution by Chen, Danzhi, Wang, Qinchuan, Dong, Minjun, Chen, Fei, Huang, Aihua, Chen, Cong, Lu, Yi, Zhao, Wenhe, Wang, Linbo

“…Abstract Background Neoadjuvant chemotherapy (NAC) has been widely applied in operable breast cancer patients. This study aim to identify the predictive…”
Get full text

Soluble Immune Checkpoint-Related Proteins in Blood Are Associated With Invasion and Progression in Non-Small Cell Lung Cancer by Wang, Qinchuan, He, Yue, Li, Wanlu, Xu, Xiaohang, Hu, Qingfeng, Bian, Zilong, Xu, Andi, Tu, Huakang, Wu, Ming, Wu, Xifeng

“…Background Immune checkpoint inhibition therapy has been achieved significant success in the treatment of non-small cell lung cancer (NSCLC). However, the role…”
Get full text

Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart by Rasmussen, Tyler P, Yuejin Wu, Mei-ling A. Joiner, Olha M. Koval, Nicholas R. Wilson, Elizabeth D. Luczak, Qinchuan Wang, Biyi Chen, Zhan Gao, Zhiyong Zhu, Brett A. Wagner, Jamie Soto, Michael L. McCormick, William Kutschke, Robert M. Weiss, Liping Yu, Ryan L. Boudreau, E. Dale Abel, Fenghuang Zhan, Douglas R. Spitz, Garry R. Buettner, Long-Sheng Song, Leonid V. Zingman, Mark E. Anderson

“…Myocardial mitochondrial Ca ²⁺ entry enables physiological stress responses but in excess promotes injury and death. However, tissue-specific in vivo…”
Get full text

Soluble immune checkpoint molecules in cancer risk, outcomes prediction, and therapeutic applications by Chen, Lin, Chao, Yuqing, Li, Wenjing, Wu, Zhixia, Wang, Qinchuan

“…Immunotherapy has emerged as a pivotal modality in cancer treatment, with immune checkpoint inhibitors effectively combating malignancies by impeding crucial…”
Get full text

CaMKII oxidation is a critical performance/disease trade-off acquired at the dawn of vertebrate evolution by Wang, Qinchuan, Hernández-Ochoa, Erick O., Viswanathan, Meera C., Blum, Ian D., Do, Danh C., Granger, Jonathan M., Murphy, Kevin R., Wei, An-Chi, Aja, Susan, Liu, Naili, Antonescu, Corina M., Florea, Liliana D., Talbot, C. Conover, Mohr, David, Wagner, Kathryn R., Regot, Sergi, Lovering, Richard M., Gao, Peisong, Bianchet, Mario A., Wu, Mark N., Cammarato, Anthony, Schneider, Martin F., Bever, Gabriel S., Anderson, Mark E.

“…Antagonistic pleiotropy is a foundational theory that predicts aging-related diseases are the result of evolved genetic traits conferring advantages early in…”
Get full text

Prediction of risk and overall survival of pancreatic cancer from blood soluble immune checkpoint-related proteins by Pan, Sai, Zhao, Wenting, Li, Yizhan, Ying, Zhijun, Luo, Yihong, Wang, Qinchuan, Li, Xiawei, Lu, Wenjie, Dong, Xin, Wu, Yulian, Wu, Xifeng

“…Immune checkpoint inhibition holds promise as a novel treatment for pancreatic ductal adenocarcinoma (PDAC). The clinical significance of soluble immune…”
Get full text

Quantitative Phosphoproteomic Study of Pressure-Overloaded Mouse Heart Reveals Dynamin-Related Protein 1 as a Modulator of Cardiac Hypertrophy by Chang, Yu-Wang, Chang, Ya-Ting, Wang, Qinchuan, Lin, Jim Jung-Ching, Chen, Yu-Ju, Chen, Chien-Chang

“…Pressure-overload stress to the heart causes pathological cardiac hypertrophy, which increases the risk of cardiac morbidity and mortality. However, the…”
Get full text

Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer by Wang, Qinchuan, Shu, Xiang, Dong, Yong, Zhou, Jichun, Teng, Rongyue, Shen, Jianguo, Chen, Yongxia, Dong, Mingjun, Zhang, Wenjun, Huang, Yasheng, Xie, Shuduo, Wei, Qun, Zhao, Wenhe, Chen, Wenjun, Yuan, Xiaoming, Qi, Xu, Wang, Linbo

“…Gastric Cancer is one of the most lethal malignancies worldwide. Gamma-glutamyl transpeptidase (GGT) is an enzyme mainly involved in cellular glutathione…”
Get full text

STAT5a Confers Doxorubicin Resistance to Breast Cancer by Regulating ABCB1 by Li, Zhaoqing, Chen, Cong, Chen, Lini, Hu, Dengdi, Yang, Xiqian, Zhuo, Wenying, Chen, Yongxia, Yang, Jingjing, Zhou, Yulu, Mao, Misha, Zhang, Xun, Xu, Ling, Ju, Siwei, Shen, Jun, Wang, Qinchuan, Dong, Minjun, Xie, Shuduo, Wei, Qun, Jia, Yunlu, Zhou, Jichun, Wang, Linbo

“…Chemoresistance is a daunting challenge to the prognosis of patients with breast cancer. Signal transducer and activator of transcription (STAT) 5a plays vital…”
Get full text

Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease by Sunuwar, Laxmi, Frkatović, Azra, Sharapov, Sodbo, Wang, Qinchuan, Neu, Heather M, Wu, Xinqun, Haritunians, Talin, Wan, Fengyi, Michel, Sarah, Wu, Shaoguang, Donowitz, Mark, McGovern, Dermot, Lauc, Gordan, Sears, Cynthia, Melia, Joanna

“…ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic…”
Get full text

Exosome: emerging biomarker in breast cancer by Jia, Yunlu, Chen, Yongxia, Wang, Qinchuan, Jayasinghe, Ushani, Luo, Xiao, Wei, Qun, Wang, Ji, Xiong, Hanchu, Chen, Cong, Xu, Bin, Hu, Wenxian, Wang, Linbo, Zhao, Wenhe, Zhou, Jichun

Get full text

Largescale multicenter study of a serum metabolite biomarker panel for the diagnosis of breast cancer by Wang, Yanzhong, An, Rui, Yu, Haitao, Dai, Yuehong, Lou, Luping, Quan, Sheng, Chen, Rongchang, Ding, Yanjun, Zhao, Hongcan, Wu, Xuanlan, Liu, Zhen, Wang, Qinchuan, Gao, Yuzhen, Xie, Xinyou, Zhang, Jun

“…Breast cancer (BC) is currently the most prevalent malignancy worldwide, and finding effective non-invasive biomarkers for routine clinical detection of BC…”
Get full text

A predictive signature for oxaliplatin and 5-fluorouracil based chemotherapy in locally advanced gastric cancer by Wang, Qinchuan, Liu, Xiyong, Chen, Chen, Chen, Jida, Xu, Beisi, Chen, Lini, Zhou, Jichun, Huang, Yasheng, Chen, Wenjun, Teng, Rongyue, Zhao, Wenhe, Jin, Lidan, Shen, Jun, Shen, Jianguo, Yen, Yun, Wang, Linbo

“…Adjuvant chemotherapy(AC) plays a substantial role in the treatment of locally advanced gastric cancer (LAGC), but the response remains poor. We aims to…”
Get full text

Patients achieved pCR during neoadjuvant chemotherapy had better outcome than adjuvant chemotherapy setting in breast cancer: A comparative study by Chen, Jida, Jin, Lidan, Chen, Lini, Bian, Zilong, Li, Zhaoqing, Cao, Shuyin, Zhou, Jichun, Xu, Ling, Zhao, Wenhe, Wang, Qinchuan

“…•Patients achieved pCR have better prognosis than adjuvant chemotherapy (AC) setting.•AC patients had better DFS than non-pCR in luminal B Her2+…”
Get full text

Deoxyribonucleic Acid 5-Hydroxymethylation in Cell-Free Deoxyribonucleic Acid, a Novel Cancer Biomarker in the Era of Precision Medicine by Xu, Ling, Zhou, Yixin, Chen, Lijie, Bissessur, Abdul Saad, Chen, Jida, Mao, Misha, Ju, Siwei, Chen, Lini, Chen, Cong, Li, Zhaoqin, Zhang, Xun, Chen, Fei, Cao, Feilin, Wang, Linbo, Wang, Qinchuan

“…Aberrant methylation has been regarded as a hallmark of cancer. 5-hydroxymethylcytosine (5hmC) is recently identified as the ten-eleven translocase (ten-eleven…”
Get full text

Corrigendum: STAT5a Confers Doxorubicin Resistance to Breast Cancer by Regulating ABCB1 by Li, Zhaoqing, Chen, Cong, Chen, Lini, Hu, Dengdi, Yang, Xiqian, Zhuo, Wenying, Chen, Yongxia, Yang, Jingjing, Zhou, Yulu, Mao, Misha, Zhang, Xun, Xu, Ling, Ju, Siwei, Shen, Jun, Wang, Qinchuan, Dong, Minjun, Xie, Shuduo, Wei, Qun, Jia, Yunlu, Zhou, Jichun, Wang, Linbo

“…[This corrects the article DOI: 10.3389/fonc.2021.697950.]…”
Get full text

Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer by Wang, Qinchaung, Gu, Jianchun, Wang, Linbo, Chang, David W, Ye, Yuanqing, Huang, Maosheng, Roth, Jack A, Wu, Xifeng

“…BackgroundRecent advances in T cell-related immunotherapy have brought remarkable progress in the treatment of non-small cell lung cancer (NSCLC). However,…”
Get full text