Search Results - "Wang, Pui"

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters by Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Jasper Fuk-Woo, Liu, Feifei, Li, Can, Chen, Yanxia, Chu, Hin, Lau, Siu-Ying, Wang, Pui, Chan, Chris Chung-Sing, Poon, Vincent Kwok-Man, Yuan, Shuofeng, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung

“…Abstract Background Clinical outcomes of the interaction between the co-circulating pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and…”
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Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction by Lau, Siu-Ying, Wang, Pui, Mok, Bobo Wing-Yee, Zhang, Anna Jinxia, Chu, Hin, Lee, Andrew Chak-Yiu, Deng, Shaofeng, Chen, Pin, Chan, Kwok-Hung, Song, Wenjun, Chen, Zhiwei, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung, Chen, Honglin

“…The emergence of SARS-CoV-2 has led to the current global coronavirus pandemic and more than one million infections since December 2019. The exact origin of…”
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Multiplexed detection of SARS-CoV-2 based on upconversion luminescence nanoprobe/MXene biosensing platform for COVID-19 point-of-care diagnostics by Song, Menglin, Ma, Yingjing, Li, Lihua, Wong, Man-Chung, Wang, Pui, Chen, Jiangkun, Chen, Honglin, Wang, Feng, Hao, Jianhua

“…We developed label-free multiplexed RNA analysis strategy based on the weakening of the FRET effect between different emission UCNPs and broad-spectrum…”
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The K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication by Song, Wenjun, Wang, Pui, Mok, Bobo Wing-Yee, Lau, Siu-Ying, Huang, Xiaofeng, Wu, Wai-Lan, Zheng, Min, Wen, Xi, Yang, Shigui, Chen, Yu, Li, Lanjuan, Yuen, Kwok-Yung, Chen, Honglin

“…Host-adaptive strategies, such as the E627K substitution in the PB2 protein, are critical for replication of avian influenza A viruses in mammalian hosts. Here…”
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An intranasal influenza virus-vectored vaccine prevents SARS-CoV-2 replication in respiratory tissues of mice and hamsters by Deng, Shaofeng, Liu, Ying, Tam, Rachel Chun-Yee, Chen, Pin, Zhang, Anna Jinxia, Mok, Bobo Wing-Yee, Long, Teng, Kukic, Anja, Zhou, Runhong, Xu, Haoran, Song, Wenjun, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Zhiwei, Yuen, Kwok-Yung, Wang, Pui, Chen, Honglin

“…Current available vaccines for COVID-19 are effective in reducing severe diseases and deaths caused by SARS-CoV-2 infection but less optimal in preventing…”
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Corrigendum to “Multiplexed detection of SARS-CoV-2 based on upconversion luminescence nanoprobe/MXene biosensing platform for COVID-19 point-of-care diagnostics” [Materials & Design 223 (2022) 1–9] by Song, Menglin, Ma, Yingjin, Li, Lihua, Wong, Man-Chung, Wang, Pui, Chen, Jiangkun, Chen, Honglin, Wang, Feng, Hao, Jianhua

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Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients by Wong, Yik Chun, Lau, Siu Ying, Wang To, Kelvin Kai, Mok, Bobo Wing Yee, Li, Xin, Wang, Pui, Deng, Shaofeng, Woo, Kin Fai, Du, Zhenglong, Li, Cun, Zhou, Jie, Chan, Jasper Fuk Woo, Yuen, Kwok Yung, Chen, Honglin, Chen, Zhiwei

“…Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains the furin cleavage Proline-Arginine-Arginine-Alanine (PRRA) motif in…”
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Attenuating innate immunity and facilitating β-coronavirus infection by NSP1 of SARS-CoV-2 through specific redistributing hnRNP A2/B1 cellular localization by Zhou, Fanghang, Wan, Qianya, Chen, Sheng, Chen, Ying, Wang, Pui-Hui, Yao, Xi, He, Ming-liang

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An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells by Huang, Xiaofeng, Zheng, Min, Wang, Pui, Mok, Bobo Wing-Yee, Liu, Siwen, Lau, Siu-Ying, Chen, Pin, Liu, Yen-Chin, Liu, Honglian, Chen, Yixin, Song, Wenjun, Yuen, Kwok-Yung, Chen, Honglin

“…Influenza virus utilizes host splicing machinery to process viral mRNAs expressed from both M and NS segments. Through genetic analysis and functional…”
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A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge by Zhou, Biao, Zhou, Runhong, Tang, Bingjie, Chan, Jasper Fuk-Woo, Luo, Mengxiao, Peng, Qiaoli, Yuan, Shuofeng, Liu, Hang, Mok, Bobo Wing-Yee, Chen, Bohao, Wang, Pui, Poon, Vincent Kwok-Man, Chu, Hin, Chan, Chris Chung-Sing, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Au, Ka-Kit, Man, Hiu-On, Lu, Lu, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok-Yung, Dang, Shangyu, Chen, Zhiwei

“…The strikingly high transmissibility and antibody evasion of SARS-CoV-2 Omicron variants have posed great challenges to the efficacy of current vaccines and…”
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Identification of influenza A nucleoprotein as an antiviral target by Kao, Richard Y, Yuen, Kwok-Yung, Yang, Dan, Lau, Lai-Shan, Tsui, Wayne H W, Hu, Lihong, Dai, Jun, Chan, Mei-Po, Chan, Che-Man, Wang, Pui, Zheng, Bo-Jian, Sun, Jian, Huang, Jian-Dong, Madar, Jason, Chen, Guanhua, Chen, Honglin, Guan, Yi

“…Influenza A remains a significant public health challenge because of the emergence of antigenically shifted or highly virulent strains. Antiviral resistance to…”
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Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines by Wang, Pui, Zheng, Min, Lau, Siu-Ying, Chen, Pin, Mok, Bobo Wing-Yee, Liu, Siwen, Liu, Honglian, Huang, Xiaofeng, Cremin, Conor J, Song, Wenjun, Chen, Yixin, Wong, Yik-Chun, Huang, Haode, To, Kelvin Kai-Wong, Chen, Zhiwei, Xia, Ningshao, Yuen, Kwok-Yung, Chen, Honglin

“…Nonstructural protein 1 (NS1) of influenza virus is a key virulence element with multifunctional roles in virus replication and a potent antagonist of host…”
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Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein by Wang, Pui, Lau, Siu-Ying, Deng, Shaofeng, Chen, Pin, Mok, Bobo Wing-Yee, Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chan, Kwok-Hung, Tam, Rachel Chun-Yee, Xu, Haoran, Zhou, Runhong, Song, Wenjun, Liu, Li, To, Kelvin Kai-Wang, Chan, Jasper Fuk-Woo, Chen, Zhiwei, Yuen, Kwok-Yung, Chen, Honglin

“…SARS-CoV-2 is of zoonotic origin and contains a PRRA polybasic cleavage motif which is considered critical for efficient infection and transmission in humans…”
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A comparison of latanoprost, bimatoprost, and travoprost in patients with elevated intraocular pressure:: A 12-week, randomized, masked-evaluator multicenter study by Parrish, Richard K, Palmberg, Paul, Sheu, Wang-Pui

“…To Internet Advance publication at ajo.com Feb 13, 2003. compare the intraocular pressure (IOP)-lowering effect and safety of latanoprost, bimatoprost, and…”
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Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals by Ye, Zi-Wei, Ong, Chon Phin, Tang, Kaiming, Fan, Yilan, Luo, Cuiting, Zhou, Runhong, Luo, Peng, Cheng, Yun, Gray, Victor Sebastien, Wang, Pui, Chu, Hin, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Honglin, Chen, Zhiwei, Yuen, Kwok-Yung, Ling, Guang Sheng, Yuan, Shuofeng, Jin, Dong-Yan

“…Live attenuated vaccines might elicit mucosal and sterilizing immunity against SARS-CoV-2 that the existing mRNA, adenoviral vector and inactivated vaccines…”
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Cellular 5'-3' mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication by Liu, Yen-Chin, Mok, Bobo Wing-Yee, Wang, Pui, Kuo, Rei-Lin, Chen, Honglin, Shih, Shin-Ru

“…Cellular 5'-3' exoribonuclease 1 (XRN1) is best known for its role as a decay factor, which by degrading 5' monophosphate RNA after the decapping of DCP2 in…”
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NF90 exerts antiviral activity through regulation of PKR phosphorylation and stress granules in infected cells by Wen, Xi, Huang, Xiaofeng, Mok, Bobo Wing-Yee, Chen, Yixin, Zheng, Min, Lau, Siu-Ying, Wang, Pui, Song, Wenjun, Jin, Dong-Yan, Yuen, Kwok-Yung, Chen, Honglin

“…NF90 was shown to exhibit broad antiviral activity against several viruses, but detailed mechanisms remain unclear. In this study, we examined the molecular…”
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GC/MS-based metabolomics reveals fatty acid biosynthesis and cholesterol metabolism in cell lines infected with influenza A virus by Lin, Shuhai, Liu, Ning, Yang, Zhu, Song, Wenjun, Wang, Pui, Chen, Honglin, Lucio, Marianna, Schmitt-Kopplin, Philippe, Chen, Guonan, Cai, Zongwei

“…Metabolomics is the downstream of systems biology and has drawn significant interest for studying the metabolic networks from cells to organisms. To profile…”
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Proteomics analysis of differential expression of cellular proteins in response to avian H9N2 virus infection in human cells by Liu, Ning, Song, Wenjun, Wang, Pui, Lee, Kimchung, Chan, Wan, Chen, Honglin, Cai, Zongwei

“…We present the first proteomic analysis on the cellular responses to avian influenza virus (H9N2) infection in a human cell line in different time courses in…”
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Single-Dose Immunization With a Chimpanzee Adenovirus-Based Vaccine Induces Sustained and Protective Immunity Against SARS-CoV-2 Infection by Li, Mingxi, Guo, Jingao, Lu, Shuaiyao, Zhou, Runhong, Shi, Hongyang, Shi, Xuanling, Cheng, Lin, Liang, Qingtai, Liu, Hongqi, Wang, Pui, Wang, Nan, Wang, Yifeng, Fu, Lili, Xing, Man, Wang, Ruoke, Ju, Bin, Liu, Li, Lau, Siu-Ying, Jia, Wenxu, Tong, Xin, Yuan, Lin, Guo, Yong, Qi, Hai, Zhang, Qi, Huang, Zhen, Chen, Honglin, Zhang, Zheng, Chen, Zhiwei, Peng, Xiaozhong, Zhou, Dongming, Zhang, Linqi

“…The development of a safe and effective vaccine against SARS-CoV-2, the causative agent of pandemic coronavirus disease-2019 (COVID-19), is a global priority…”
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