Search Results - "Wang, Nancy"
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Leptomeningeal metastasis from systemic cancer: Review and update on management
Published in Cancer (01-01-2018)“…Leptomeningeal metastasis is an uncommon and typically late complication of cancer with a poor prognosis and limited treatment options. Diagnosis is often…”
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An atopic dermatitis-like murine model by skin-brushed cockroach Per a 2 and oral tolerance induction by Lactococcus lactis-derived Per a 2
Published in PloS one (07-09-2023)“…Atopic dermatitis (AD) is a complex, chronic inflammatory skin disease. An estimated 57.5% of asthmatic patients and 50.7% of rhinitis patients are allergic to…”
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3
Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV‑2 3CLpro)
Published in Journal of medicinal chemistry (24-02-2022)“…Starting from the MLPCN probe compound ML300, a structure-based optimization campaign was initiated against the recent severe acute respiratory syndrome…”
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4
New Directions in Anti-Angiogenic Therapy for Glioblastoma
Published in Neurotherapeutics (01-04-2017)“…Anti-angiogenic therapy has become an important component in the treatment of many solid tumors given the importance of adequate blood supply for tumor growth…”
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One-Step Synthesis of Isocoumarins and 3‑Benzylidenephthalides via Ligandless Pd-Catalyzed Oxidative Coupling of Benzoic Acids and Vinylarenes
Published in Journal of organic chemistry (05-04-2013)“…A straightforward synthetic method for the preparation of isocoumarins and 3-benzylidenephthalides via C–H olefination and oxidative coupling of readily…”
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Indoor aeroallergens from American cockroaches and mites initiate atopic march via cutaneous contact in a murine model
Published in PloS one (27-07-2023)“…The progression of allergic diseases from atopic dermatitis in childhood to other allergic conditions such as asthma in later life is often referred to as the…”
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Prostate Magnetic Resonance Imaging Interpretation Varies Substantially Across Radiologists
Published in European urology focus (01-07-2019)“…Multiparametric magnetic resonance imaging (mpMRI) interpreted by experts is a powerful tool for diagnosing prostate cancer. However, the generalizability of…”
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A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
Published in Cancer cell (14-05-2018)“…Gliomas comprise heterogeneous malignant glial and stromal cells. While blood vessel co-option is a potential mechanism to escape anti-angiogenic therapy, the…”
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Addressing Social Determinants of Health from the Emergency Department through Social Emergency Medicine
Published in The western journal of emergency medicine (01-07-2016)Get full text
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10
Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation
Published in Nature methods (01-12-2012)“…A collection of opsins for two-photon modulation of neuronal activity in vitro and in vivo is presented in this resource. The opsins have kinetic, expression…”
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Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas
Published in Nature communications (11-05-2021)“…Immune checkpoint blockers (ICBs) have failed in all phase III glioblastoma (GBM) trials. Here, we show that regulatory T (Treg) cells play a key role in GBM…”
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Effectiveness of a Staged US and CT Protocol for the Diagnosis of Pediatric Appendicitis: Reducing Radiation Exposure in the Age of ALARA
Published in Radiology (01-04-2011)“…To evaluate the effectiveness of a staged ultrasonography (US) and computed tomography (CT) imaging protocol for the accurate diagnosis of suspected…”
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13
Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection
Published in Immunity (Cambridge, Mass.) (15-09-2020)“…Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necroptosis, and apoptosis during…”
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Disparities in COVID-19 testing and outcomes among Asian American and Pacific Islanders: an observational study in a large health care system
Published in BMC public health (06-02-2023)“…The COVID-19 pandemic has disproportionately impacted racial and ethnic minorities in the United States, including Asian Americans, Native Hawaiians and…”
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Interfacility transfer and mortality for patients with ruptured abdominal aortic aneurysm
Published in Journal of vascular surgery (01-09-2014)“…Objective Patients receiving interfacility transfer to a higher level of medical care for ruptured abdominal aortic aneurysms (rAAAs) are an important minority…”
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MAIT cells protect against pulmonary Legionella longbeachae infection
Published in Nature communications (22-08-2018)“…Mucosal associated invariant T (MAIT) cells recognise conserved microbial metabolites from riboflavin synthesis. Striking evolutionary conservation and…”
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Oral Administration of Lactococcus lactis Expressing Mite and Cockroach Major Allergens Alleviates Progression of Atopic March in a Mouse Model
Published in Allergy, asthma & immunology research (01-09-2024)“…Atopic march is defined as the development of atopic dermatitis in early childhood. We recently developed an atopic march mouse model through skin…”
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Teaching Urologists “How to Read Multi-Parametric Prostate MRIs Using PIRADSv2”: Results of an iBook Pilot Study
Published in Urology (Ridgewood, N.J.) (01-09-2019)“…To create an online resource that teaches urologists how to interpret prostate multiparametric magnetic resonance imaging (mpMRI). As prostate mpMRI becomes…”
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Oral edible plant vaccine containing hypoallergen of American cockroach major allergen Per a 2 prevents roach-allergic asthma in a murine model
Published in PloS one (30-07-2018)“…American cockroaches (Periplaneta americana) are an important indoor allergen source and a major risk factor for exacerbations and poor control of asthma. We…”
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The Anti-Inflammatory Effect of Lactococcus lactis -Ling-Zhi 8 on Ameliorating Atherosclerosis and Nonalcoholic Fatty Liver in High-Fat Diet Rabbits
Published in International journal of molecular sciences (20-10-2024)“…Inflammation plays a crucial role in atherosclerosis and nonalcoholic fatty liver disease (NAFLD). We previously engineered a recombinant strain expressing the…”
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