Search Results - "Wang, Maple"

Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization by Wang, Pengfei, Casner, Ryan G., Nair, Manoj S., Wang, Maple, Yu, Jian, Cerutti, Gabriele, Liu, Lihong, Kwong, Peter D., Huang, Yaoxing, Shapiro, Lawrence, Ho, David D.

“…The emergence of SARS-CoV-2 variants has raised concerns about altered sensitivity to antibody-mediated immunity. The relative resistance of SARS-CoV-2…”
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Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5 by Wang, Qian, Guo, Yicheng, Iketani, Sho, Nair, Manoj S., Li, Zhiteng, Mohri, Hiroshi, Wang, Maple, Yu, Jian, Bowen, Anthony D., Chang, Jennifer Y., Shah, Jayesh G., Nguyen, Nadia, Chen, Zhiwei, Meyers, Kathrine, Yin, Michael T., Sobieszczyk, Magdalena E., Sheng, Zizhang, Huang, Yaoxing, Liu, Lihong, Ho, David D.

“…SARS-CoV-2 Omicron subvariants BA.2.12.1 and BA.4/5 have surged notably to become dominant in the United States and South Africa, respectively 1 , 2 . These…”
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Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7 by Wang, Pengfei, Nair, Manoj S., Liu, Lihong, Iketani, Sho, Luo, Yang, Guo, Yicheng, Wang, Maple, Yu, Jian, Zhang, Baoshan, Kwong, Peter D., Graham, Barney S., Mascola, John R., Chang, Jennifer Y., Yin, Michael T., Sobieszczyk, Magdalena, Kyratsous, Christos A., Shapiro, Lawrence, Sheng, Zizhang, Huang, Yaoxing, Ho, David D.

“…The COVID-19 pandemic has had widespread effects across the globe, and its causative agent, SARS-CoV-2, continues to spread. Effective interventions need to be…”
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Antibody evasion properties of SARS-CoV-2 Omicron sublineages by Iketani, Sho, Liu, Lihong, Guo, Yicheng, Liu, Liyuan, Chan, Jasper F.-W., Huang, Yiming, Wang, Maple, Luo, Yang, Yu, Jian, Chu, Hin, Chik, Kenn K.-H., Yuen, Terrence T.-T., Yin, Michael T., Sobieszczyk, Magdalena E., Huang, Yaoxing, Yuen, Kwok-Yung, Wang, Harris H., Sheng, Zizhang, Ho, David D.

“…The identification of the Omicron (B.1.1.529.1 or BA.1) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Botswana in November 2021 1…”
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Defining the risk of SARS-CoV-2 variants on immune protection by Ghedin, Elodie, Krammer, Florian, Grifoni, Alba, Alter, Galit, Baric, Ralph S., Barouch, Dan H., Bloyet, Louis-Marie, Bonenfant, Gaston, Boon, Adrianus C. M., Boritz, Eli A., Bratt, Debbie L., Bricker, Traci L., Brown, Liliana, Buchser, William J., Carreño, Juan Manuel, Darling, Tamarand L., Di, Han, Dittmann, Meike, Doria-Rose, Nicole A., Douek, Daniel C., Drosten, Christian, Edara, Venkata-Viswanadh, Ellebedy, Ali, Fabrizio, Thomas P., Ferrari, Guido, Fischer, Will M., Florence, William C., Franks, John, García-Sastre, Adolfo, Godzik, Adam, Gonzalez-Reiche, Ana Silvia, Gordon, Aubree, Haagmans, Bart L., Halfmann, Peter J., Holbrook, Michael R., James, Sarah L., Jaroszewski, Lukasz, Johnson, Robert M., Jones, Terry C., Kawaoka, Yoshihiro, Kercher, Lisa, Koopmans, Marion P. G., Korber, Bette, Koren, Eilay, LeGresley, Eric B., Liu, Zhuoming, Livingston, Brandi, Logue, James P., Luo, Yang, McDermott, Adrian B., McElrath, Margaret J., Menachery, Vineet D., Mühlemann, Barbara, Munt, Jenny E., Nair, Manoj S., Netzl, Antonia, O’Dell, Sijy, Pekosz, Andrew, Perlman, Stanley, Pontelli, Marjorie C., Rothlauf, Paul W., Sacharen, Sinai, Scheuermann, Richard H., Schmidt, Stephen D., Schotsaert, Michael, Schultz-Cherry, Stacey, Seder, Robert A., Sedova, Mayya, Shabman, Reed S., Shen, Xiaoying, Shi, Pei-Yong, Shukla, Maulik, Simon, Viviana, Stumpf, Spencer, Thackray, Larissa B., Theiler, James, Thomas, Paul G., Trifkovic, Sanja, Turner, Samuel A., Vakaki, Maria A., van Bakel, Harm, VanBlargan, Laura A., Vincent, Leah R., Wallace, Zachary S., Wang, Li, Wang, Maple, Wang, Pengfei, Wang, Wei, Webby, Richard J., Wentworth, David E., Whelan, Sean P. J., Whitener, Bradley M., Wilks, Samuel H., Xie, Xuping, Ying, Baoling, Zhou, Bin, Hertz, Tomer, Smith, Derek J., Diamond, Michael S., Suthar, Mehul S.

“…The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants jeopardizes the protective antiviral immunity induced after…”
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Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain by Cerutti, Gabriele, Guo, Yicheng, Wang, Pengfei, Nair, Manoj S., Wang, Maple, Huang, Yaoxing, Yu, Jian, Liu, Lihong, Katsamba, Phinikoula S., Bahna, Fabiana, Reddem, Eswar R., Kwong, Peter D., Ho, David D., Sheng, Zizhang, Shapiro, Lawrence

“…Antibodies that potently neutralize SARS-CoV-2 target mainly the receptor-binding domain or the N-terminal domain (NTD). Over a dozen potently neutralizing…”
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Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability by Gorman, Jason, Cheung, Crystal Sao-Fong, Duan, Zhijian, Ou, Li, Wang, Maple, Chen, Xuejun, Cheng, Cheng, Biju, Andrea, Sun, Yaping, Wang, Pengfei, Yang, Yongping, Zhang, Baoshan, Boyington, Jeffrey C., Bylund, Tatsiana, Charaf, Sam, Chen, Steven J., Du, Haijuan, Henry, Amy R., Liu, Tracy, Sarfo, Edward K., Schramm, Chaim A., Shen, Chen-Hsiang, Stephens, Tyler, Teng, I-Ting, Todd, John-Paul, Tsybovsky, Yaroslav, Verardi, Raffaello, Wang, Danyi, Wang, Shuishu, Wang, Zhantong, Zheng, Cheng-Yan, Zhou, Tongqing, Douek, Daniel C., Mascola, John R., Ho, David D., Ho, Mitchell, Kwong, Peter D.

“…Lassa virus (LASV) infection is expanding outside its traditionally endemic areas in West Africa, posing a pandemic biothreat. LASV-neutralizing antibodies,…”
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An optimized thermodynamics integration protocol for identifying beneficial mutations in antibody design by Sheng, Zizhang, Bimela, Jude S, Wang, Maple, Li, Zhiteng, Guo, Yicheng, Ho, David D

“…Accurate identification of beneficial mutations is central to antibody design. Many knowledge-based (KB) computational approaches have been developed to…”
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A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses by Wang, Pengfei, Casner, Ryan G., Nair, Manoj S., Yu, Jian, Guo, Yicheng, Wang, Maple, Chan, Jasper F.-W., Cerutti, Gabriele, Iketani, Sho, Liu, Lihong, Sheng, Zizhang, Chen, Zhiwei, Yuen, Kwok-Yung, Kwong, Peter D., Huang, Yaoxing, Shapiro, Lawrence, Ho, David D.

“…The repeated emergence of highly pathogenic human coronaviruses as well as their evolving variants highlight the need to develop potent and broad-spectrum…”
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Design of a flexing organ-chip to model in situ loading of the intervertebral disc by McKinley, Jonathan P., Montes, Andre R., Wang, Maple N., Kamath, Anuya R., Jimenez, Gissell, Lim, Jianhua, Marathe, Siddharth A., Mofrad, Mohammad R. K., O’Connell, Grace D.

“…The leading cause of disability of all ages worldwide is severe lower back pain. To address this untreated epidemic, further investigation is needed into the…”
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Genomic Epidemiology and Serology Associated with a SARS-CoV-2 R.1 Variant Outbreak in New Jersey by Mathema, Barun, Chen, Liang, Wang, Pengfei, Cunningham, Marcus H, Mediavilla, Jose R, Chow, Kar Fai, Luo, Yang, Zhao, Yanan, Composto, Kaelea, Zuckerman, Jerry, Zody, Michael C, Wilson, Nancy, Lee, Annie, Oschwald, Dayna M, Liu, Lihong, Iketani, Sho, Germer, Soren, Fennessey, Samantha, Wang, Maple, Kramer, Yael, Toole, Patricia, Maniatis, Tom, Ho, David D, Perlin, David S, Kreiswirth, Barry N

“…Examining the neutralizing capacity of monoclonal antibodies (MAbs) used to treat COVID-19, as well as antibodies recovered from unvaccinated, previously…”
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Elucidation of lipid nanoparticle surface structure in mRNA vaccines by Wang, Mingzhang Maple, Wappelhorst, Caitlin N., Jensen, Erika L., Chi, Ying-Chih Thomas, Rouse, Jason C., Zou, Qin

“…Lipid nanoparticles (LNPs) have been used as a carrier for messenger RNA (mRNA) vaccines. Surface properties of LNPs are important to the stability and…”
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Changes in serum-neutralizing antibody potency and breadth post-SARS-CoV-2 mRNA vaccine boost by Nair, Manoj S., Ribeiro, Ruy M., Wang, Maple, Bowen, Anthony D., Liu, Lihong, Guo, Yicheng, Chang, Jennifer Y., Wang, Pengfei, Sheng, Zizhang, Sobieszczyk, Magdalena E., Perelson, Alan S., Huang, Yaoxing, Ho, David D.

“…A better understanding of the durability and breadth of serum-neutralizing antibody responses against multiple severe acute respiratory syndrome coronavirus 2…”
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Ad26.COV2.S boosts antibody and T-cell responses following BNT162b2 vaccination by Iketani, Sho, Liu, Lihong, Nair, Manoj S., Chandrashekar, Abishek, Mohri, Hiroshi, Wang, Maple, Barouch, Dan H., Huang, Yaoxing, Ho, David D.

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Development and performance of a point-of-care rapid antigen test for detection of SARS-COV-2 variants by Liu, Lihong, Meyers, Kathrine, Purpura, Lawrence J., Nguyen, Nadia, Mohri, Hiroshi, Chang, Jennifer Y., Annavajhala, Medini K., Lopez, Leo, Lee, Sang Won, Shah, Jayesh, Lane, Benjamin, Cantos, Anyelina, Tukuru, Sade A., Guo, Yicheng, Ford, Kenra, Chiu, Yueh-Ting, Sheng, Zizhang, Choesang, Tenzin, Castor, Delivette, Wang, Maple, Pili, Christina, Van Hoy, Michael N., Wallach, Andrew, Horton, Jamie, Chen, Zhiqiang, Rosenthal, Susan, McLaren, Son, Jiang, Baowei, Wang, Frank, Lu, Helen H., Uhlemann, Anne-Catrin, Ho, David D., Yin, Michael T.

“…•A unique rapid Sars-CoV2 antigen test was developed with two pairs of high-affinity monoclonal antibodies.•Demonstrated high sensitivity for samples with…”
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Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants by Wang, Qian, Iketani, Sho, Li, Zhiteng, Liu, Liyuan, Guo, Yicheng, Huang, Yiming, Bowen, Anthony D., Liu, Michael, Wang, Maple, Yu, Jian, Valdez, Riccardo, Lauring, Adam S., Sheng, Zizhang, Wang, Harris H., Gordon, Aubree, Liu, Lihong, Ho, David D.

“…The BQ and XBB subvariants of SARS-CoV-2 Omicron are now rapidly expanding, possibly due to altered antibody evasion properties deriving from their additional…”
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Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2 by Liu, Lihong, Iketani, Sho, Guo, Yicheng, Chan, Jasper F.-W., Wang, Maple, Liu, Liyuan, Luo, Yang, Chu, Hin, Huang, Yiming, Nair, Manoj S., Yu, Jian, Chik, Kenn K.-H., Yuen, Terrence T.-T., Yoon, Chaemin, To, Kelvin K.-W., Chen, Honglin, Yin, Michael T., Sobieszczyk, Magdalena E., Huang, Yaoxing, Wang, Harris H., Sheng, Zizhang, Yuen, Kwok-Yung, Ho, David D.

“…The B.1.1.529/Omicron variant of SARS-CoV-2 was only recently detected in southern Africa, but its subsequent spread has been extensive, both regionally and…”
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Preparation of Functionalized Mesoporous Silica Nanoparticles as Mass Tags for Potential Applications in Mass Cytometry by Li, Xiaochong, Liu, Yang, Zhang, Yefeng, Majonis, Daniel, Wang, Maple, Fashandi, Maryam, Winnik, Mitchell A.

“…Mass cytometry (MC) is an emerging and powerful bioanalytical technique for high-dimensional single-cell analysis. While metal-chelating polymers (MCPs) have…”
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Resistance of SARS-CoV-2 omicron subvariant BA.4.6 to antibody neutralisation by Wang, Qian, Li, Zhiteng, Ho, Jerren, Guo, Yicheng, Yeh, Andre Yanchen, Mohri, Hiroshi, Liu, Michael, Wang, Maple, Yu, Jian, Shah, Jayesh G, Chang, Jennifer Y, Herbas, Favio, Yin, Michael T, Sobieszczyk, Magdalena E, Sheng, Zizhang, Liu, Lihong, Ho, David D

“…All the spike proteins from BA.4/5 sublineages, and those of BA.4/5 carrying point mutations of R346S and N658S, showed similar binding affinities to ACE2,…”
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SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells by Han, Yuling, Zhu, Jiajun, Yang, Liuliu, Nilsson-Payant, Benjamin E., Hurtado, Romulo, Lacko, Lauretta A., Sun, Xiaolu, Gade, Aravind R., Higgins, Christina A., Sisso, Whitney J., Dong, Xue, Wang, Maple, Chen, Zhengming, Ho, David D., Pitt, Geoffrey S., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing

“…Increasing evidence suggests that cardiac arrhythmias are frequent clinical features of coronavirus disease 2019 (COVID-19). Sinus node damage may lead to…”
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