Search Results - "Wang, Manni"

Targeting TGF-β signal transduction for fibrosis and cancer therapy by Peng, Dandan, Fu, Minyang, Wang, Manni, Wei, Yuquan, Wei, Xiawei

“…Transforming growth factor β (TGF-β) has long been identified with its intensive involvement in early embryonic development and organogenesis, immune…”
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Cancer vaccines as promising immuno-therapeutics: platforms and current progress by Liu, Jian, Fu, Minyang, Wang, Manni, Wan, Dandan, Wei, Yuquan, Wei, Xiawei

“…Research on tumor immunotherapy has made tremendous progress in the past decades, with numerous studies entering the clinical evaluation. The cancer vaccine is…”
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CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer by Wang, Binhan, Wang, Manni, Ao, Danyi, Wei, Xiawei

“…Chemokine C-X-C motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays an important role in the immune system. The interaction between…”
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Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials by Cheng, Yuan, He, Cai, Wang, Manni, Ma, Xuelei, Mo, Fei, Yang, Shengyong, Han, Junhong, Wei, Xiawei

“…Epigenetic alternations concern heritable yet reversible changes in histone or DNA modifications that regulate gene activity beyond the underlying sequence…”
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Targeting DNA repair pathway in cancer: Mechanisms and clinical application by Wang, Manni, Chen, Siyuan, Ao, Danyi

“…Over the last decades, the growing understanding on DNA damage response (DDR) pathways has broadened the therapeutic landscape in oncology. It is becoming…”
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Signaling pathways in the regulation of cancer stem cells and associated targeted therapy by Manni, Wang, Min, Wu

“…Cancer stem cells (CSCs) are defined as a subpopulation of malignant tumor cells with selective capacities for tumor initiation, self‐renewal, metastasis, and…”
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Myeloid-Derived Suppressor Cells Promote Metastasis in Breast Cancer After the Stress of Operative Removal of the Primary Cancer by Ma, Xuelei, Wang, Manni, Yin, Tao, Zhao, Yunuo, Wei, Xiawei

“…Objective: To investigate the role of myeloid-derived suppressor cells (MDSC) in cancer progression after the stress of operative removal and the potential…”
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Molecular mechanisms and clinical management of cancer bone metastasis by Wang, Manni, Xia, Fan, Wei, Yuquan, Wei, Xiawei

“…As one of the most common metastatic sites of malignancies, bone has a unique microenvironment that allows metastatic tumor cells to grow and flourish. The…”
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Targeting inflammation as cancer therapy by Wang, Manni, Chen, Siyuan, He, Xuemei, Yuan, Yong, Wei, Xiawei

“…Inflammation has accompanied human beings since the emergence of wounds and infections. In the past decades, numerous efforts have been undertaken to explore…”
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Survival and prognostic analysis of preoperative inflammatory markers in patients undergoing surgical resection for laryngeal squamous cell carcinoma by Chen, Linyan, Zeng, Hao, Yang, Jiapeng, Lu, Yuqing, Zhang, Dan, Wang, Jinggan, Kuang, Chienyun, Zhu, Sha, Wang, Manni, Ma, Xuelei

“…To estimate the prognostic value of inflammatory markers in patients with laryngeal squamous cell carcinoma (LSCC). A total of 361 resected LSCC patients were…”
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JMJD family proteins in cancer and inflammation by Manni, Wang, Jianxin, Xue, Weiqi, Hong, Siyuan, Chen, Huashan, Shi

“…The occurrence of cancer entails a series of genetic mutations that favor uncontrollable tumor growth. It is believed that various factors collectively…”
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DNA-PK inhibition by M3814 enhances chemosensitivity in non-small cell lung cancer by Wang, Manni, Chen, Siyuan, Wei, Yuquan, Wei, Xiawei

“…A significant proportion of non-small cell lung cancer (NSCLC) patients experience accumulating chemotherapy-related adverse events, motivating the design of…”
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Night Shift Work Increases the Risks of Multiple Primary Cancers in Women: A Systematic Review and Meta-analysis of 61 Articles by Yuan, Xia, Zhu, Chenjing, Wang, Manni, Mo, Fei, Du, Wei, Ma, Xuelei

“…A growing number of studies have examined associations between night shift work and the risks of common cancers among women, with varying conclusions. We did a…”
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Computed tomography-based deep-learning prediction of induction chemotherapy treatment response in locally advanced nasopharyngeal carcinoma by Yang, Yuhan, Wang, Manni, Qiu, Ke, Wang, Yixi, Ma, Xuelei

“…Background Deep learning methods have great potential to predict treatment response. The objective of this study was to evaluate and validate the predictive…”
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The obesity paradox in intracerebral hemorrhage: a systematic review and meta-analysis by Wang, Zexu, Wang, Jie, Wang, Jiayan, Liao, Yinghua, Hu, Xin, Wang, Manni

“…Intracerebral hemorrhage (ICH) has a mortality rate which can reach 30-40%. Compared with other diseases, obesity is often associated with lower mortality;…”
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Involvement of TLR4 signaling regulated-COX2/PGE2 axis in liver fibrosis induced by Schistosoma japonicum infection by Chen, Lan, Ji, Xiaofang, Wang, Manni, Liao, Xiaoyan, Liang, Cuiying, Tang, Juanjuan, Wen, Zhencheng, Dominique, Ferrandon, Li, Zi

“…Abstract Background Hepatic stellate cell (HSC) activation plays a pivotal role in hepatic inflammation and liver fibrosis. TLR4 pathway activation has been…”
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Retraction: Night Shift Work Increases the Risks of Multiple Primary Cancers in Women: A Systematic Review and Meta-analysis of 61 Articles by Yuan, Xia, Zhu, Chenjing, Wang, Manni, Mo, Fei, Du, Wei, Ma, Xuelei

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Positive Feedback Regulation between Transglutaminase 2 and Toll-Like Receptor 4 Signaling in Hepatic Stellate Cells Correlates with Liver Fibrosis Post Schistosoma japonicum Infection by Wen, Zhencheng, Ji, Xiaofang, Tang, Juanjuan, Lin, Guiying, Xiao, Linzhuo, Liang, Cuiying, Wang, Manni, Su, Fang, Ferrandon, Dominique, Li, Zi

“…Liver fibrosis induced by infection is characterized by the accumulation of extracellular matrix (ECM). The activated and differentiated hepatic stellate cells…”
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FcγRIIb blockage: a promising immunotherapy target for severe COVID-19 by He, Xuemei, Wang, Manni, Wu, Min

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Constrained surfaces: promising therapeutic targets for COVID-19 determined by systematically mutational analysis by Wang, Manni, Lan, Tianxia, Wang, Wei

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