Search Results - "Wang, Lily Q."

Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics by Bosc, Elodie, Anastasie, Julie, Soualmia, Feryel, Coric, Pascale, Kim, Ju Youn, Wang, Lily Q., Lacin, Gullen, Zhao, Kaitao, Patel, Ronak, Duplus, Eric, Tixador, Philippe, Sproul, Andrew A., Brugg, Bernard, Reboud-Ravaux, Michelle, Troy, Carol M., Shelanski, Michael L., Bouaziz, Serge, Karin, Michael, El Amri, Chahrazade, Jacotot, Etienne D.

“…Caspase-2 (Casp2) is a promising therapeutic target in several human diseases, including nonalcoholic steatohepatitis (NASH) and Alzheimer’s disease (AD)…”
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PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis by Kim, Ju Youn, Wang, Lily Q., Sladky, Valentina C., Oh, Tae Gyu, Liu, Junlai, Trinh, Kaitlyn, Eichin, Felix, Downes, Michael, Hosseini, Mojgan, Jacotot, Etienne D., Evans, Ronald M., Villunger, Andreas, Karin, Michael

“…Sterol deficiency triggers SCAP-mediated SREBP activation, whereas hypernutrition together with ER-stress activate SREBP1/2 via caspase-2. Whether these…”
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