Search Results - "Wang, Leitong"

Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5 by Lai, Guangrui, Wang, Leitong, Li, Zhen, Zhao, Yanyan

“…Homocysteine (Hcy) is an independent risk factor of congenital heart disease (CHD), but its exact underlying mechanism is unclear. In this study, we collected…”
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cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases by Wang, Leitong, Lai, Guangrui, Chu, Guoming, Liang, Xiaoyan, Zhao, Yanyan

“…Cardiac myosin binding protein C (cMyBP-C) is a cardiac structural and regulatory protein; mutations of cMyBP-C are frequently associated with hypertrophic…”
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Role of Nkx2.5 in H₂O₂-induced Nsd1 suppression by Liang, Xiaoyan, Chu, Guoming, Wang, Leitong, Lai, Guangrui, Zhao, Yanyan

“…Nuclear receptor–binding SET domain–containing protein 1 (Nsd1) acts as a histone lysine methyltransferase, and its role in oxidative stress–related abnormal…”
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Influence of Long Non-Coding RNAs on Human Oocyte Development by Wang, Leitong, Li, Baoshan, Cheng, Dongkai

“…Recent research findings have highlighted the pivotal roles played by lncRNAs in both normal human development and disease pathogenesis. LncRNAs are expressed…”
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miR-137 downregulates c-kit expression in acute myeloid leukemia by Hu, Yanping, Dong, Xiaolong, Chu, Guoming, Lai, Guangrui, Zhang, Bijun, Wang, Leitong, Zhao, Yanyan

“…Highlights • miR-137 targets the 3′-UTR of c-kit.. • miR-137 suppresses the expression and activities of c-kit in AML cell. • Expression of miR-137 inversely…”
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Role of Nkx2.5 in H 2 O 2 -induced Nsd1 suppression by Liang, Xiaoyan, Chu, Guoming, Wang, Leitong, Lai, Guangrui, Zhao, Yanyan

“…Nuclear receptor-binding SET domain-containing protein 1 (Nsd1) acts as a histone lysine methyltransferase, and its role in oxidative stress-related abnormal…”
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Decreased Amino Acid Concentrations are Involved in Congenital Heart Disease by Lai, Guangrui, Li, Xiaoming, Zhang, Bijun, Wang, Leitong, He, Rong, Zhao, Yanyan

“…Congenital heart disease (CHD) is the most common malformation in China. In this study, we determined whether amino acids (AAs) in the amniotic fluid (AF) of…”
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Differences in IGF axis-related proteins in amniotic fluid of trisomy 21 and trisomy 18 using a multiple reaction monitoring approach by Lai, Guangrui, Zhang, Yuanyuan, Wang, Leitong, Zhang, Bijun, Zheng, Gaoyan, Wang, Xuanyi, Zhao, Xiaoqiu, Gao, Haiming, Zhao, Yanyan

“…ABSTRACT Objective Trisomy 21 and trisomy 18 are the two most common chromosomal anomalies in live births. To find new biomarkers for aneuploidies and…”
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