Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review

Kawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD, while cardiac involvement may occur in up to 25% of patients, generally in the second week...

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Bibliographic Details
Published in:	Italian journal of pediatrics Vol. 49; no. 1; p. 60
Main Authors:	Jiao, Wenyan, Wei, Li, Jiao, Fuyong, Pjetraj, Dorina, Feng, Jianying, Wang, Jvyan, Catassi, Carlo, Gatti, Simona
Format:	Journal Article
Language:	English
Published:	England BioMed Central 04-06-2023 BMC
Subjects:	Age Aneurysm Aneurysms Anticoagulants Babies Blood platelets Blood tests Cardiovascular disease Case Report Case reports Children Children & youth Coronary artery Coronary artery aneurysm Coronary vessels Enzymes Fever Heart Infants Infections Inflammatory diseases Kawasaki disease Leukocytes Literature reviews Liver Mortality Mucocutaneous lymph node syndrome Pediatrics Thrombosis Ultrasonic imaging Vasculitis Veins & arteries Japan Case report Kawasaki disease Children Thrombosis Coronary artery aneurysm
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Summary:	Kawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD, while cardiac involvement may occur in up to 25% of patients, generally in the second week of the disease. We describe the case of KD developing in a 3-month infant, with an early occurrence of coronary artery aneurysm after only 3 days of fever, complicated by thrombosis, requiring aggressive treatments. Time of development of cardiac complications can be different in young infants with KD and both diagnostic criteria and treatment indications should be individualized in this class of age.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Review-3 content type line 23 ObjectType-Feature-5 ObjectType-Article-4 ObjectType-Report-1
ISSN:	1824-7288 1720-8424 1824-7288
DOI:	10.1186/s13052-023-01478-9