Search Results - "Wang, Junpei"

Long Non-Coding RNA in the Pathogenesis of Cancers by Chi, Yujing, Wang, Di, Wang, Junpei, Yu, Weidong, Yang, Jichun

“…The incidence and mortality rate of cancer has been quickly increasing in the past decades. At present, cancer has become the leading cause of death worldwide…”
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Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis by Wang, Junpei, Yang, Weili, Chen, Zhenzhen, Chen, Ji, Meng, Yuhong, Feng, Biaoqi, Sun, Libo, Dou, Lin, Li, Jian, Cui, Qinghua, Yang, Jichun

“…Mammalian genomes encode a huge number of long noncoding RNAs (lncRNAs) with unknown functions. This study determined the role and mechanism of a new lncRNA,…”
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Hepatic Activation of the FAM3C-HSF1-CaM Pathway Attenuates Hyperglycemia of Obese Diabetic Mice by Chen, Zhenzhen, Ding, Liwei, Yang, Weili, Wang, Junpei, Chen, Liming, Chang, Yongsheng, Geng, Bin, Cui, Qinghua, Guan, Youfei, Yang, Jichun

“…FAM3C is a member of the family with sequence similarity 3 (FAM3) gene family, and this study determined its role and mechanism in regulation of hepatic…”
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Effects of foliar application of amino acid-chelated selenite on photosynthetic characteristics of peanut (Arachis hypogaea L.) leaves at the podding stage by Wang, Ying, Zhu, Qing, Wang, Zhiwei, Wang, Junpei, Wang, Zhen, Yu, Feiyan, Zhang, Lianhe

“…Foliar application of selenium (Se) is an effective measure to increase Se concentrations in peanut pods. However, how the foliar application of amino…”
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Comparison Analysis of Dysregulated LncRNA Profile in Mouse Plasma and Liver after Hepatic Ischemia/Reperfusion Injury by Chen, Zhenzhen, Luo, Yanjin, Yang, Weili, Ding, Liwei, Wang, Junpei, Tu, Jian, Geng, Bin, Cui, Qinghua, Yang, Jichun

“…Long noncoding RNAs (LncRNAs) have been believed to be the major transcripts in various tissues and organs, and may play important roles in regulation of many…”
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A bioinformatics method for predicting long noncoding RNAs associated with vascular disease by Li, JianWei, Gao, Cheng, Wang, YuChen, Ma, Wei, Tu, Jian, Wang, JunPei, Chen, ZhenZhen, Kong, Wei, Cui, QingHua

“…Long noncoding RNAs（lncRNAs）play important roles in human diseases including vascular disease.Given the large number of lncRNAs,however,whether the majority of…”
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Fidgetin interacting with microtubule end binding protein EB3 affects axonal regrowth in spinal cord injury by Ma, Chao, Wang, Junpei, Tu, Qifeng, Bo, Weijuan, Hu, Zunlu, Zhuo, Run, Wu, Ronghua, Dong, Zhangji, Qiang, Liang, Liu, Yan, Liu, Mei

“…[INLINE:1] Fidgetin, a microtubule-severing enzyme, regulates neurite outgrowth, axonal regeneration, and cell migration by trimming off the labile domain of…”
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FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice by Chen, Zhenzhen, Wang, Junpei, Yang, Weili, Chen, Ji, Meng, Yuhong, Feng, Biaoqi, Chi, Yujing, Geng, Bin, Zhou, Yong, Cui, Qinghua, Yang, Jichun

“…FAM3C, a member of FAM3 gene family, has been shown to improve insulin resistance and hyperglycemia in obese mice. This study further determined whether FAM3C…”
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FAM3 gene family: A promising therapeutical target for NAFLD and type 2 diabetes by Zhang, Xiaoyan, Yang, Weili, Wang, Junpei, Meng, Yuhong, Guan, Youfei, Yang, Jichun

“…Non-alcoholic fatty liver disease (NAFLD) and diabetes are severe public health issues worldwide. The Family with sequence similarity 3 (FAM3) gene family…”
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CircRNA_01477 influences axonal growth via regulating miR-3075/FosB/Stat3 axis by Qian, Xiaowei, Lin, Ge, Wang, Junpei, Zhang, Siming, Ma, Jingyi, Yu, Bin, Wu, Ronghua, Liu, Mei

“…Circular RNAs (circRNAs) are important for the development and regeneration of the nervous system. We investigated the differential expression profiles of…”
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FAM3C‐YY1 axis is essential for TGFβ‐promoted proliferation and migration of human breast cancer MDA‐MB‐231 cells via the activation of HSF1 by Yang, Weili, Feng, Biaoqi, Meng, Yuhong, Wang, Junpei, Geng, Bin, Cui, Qinghua, Zhang, Hongquan, Yang, Yang, Yang, Jichun

“…Family with sequence similarity three member C (FAM3C) (interleukin‐like EMT inducer [ILEI]), heat shock factor 1 (HSF1) and Ying‐Yang 1 (YY1) have been…”
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Cell Development Enhanced Bionic Silk Hydrogel on Remodeling Immune Pathogenesis of Spinal Cord Injury via M2 Polarization of Microglial by Ling, Jue, Huang, Tingting, Wu, Ronghua, Ma, Chao, Lin, Ge, Zhou, Zhihao, Wang, Junpei, Tu, Qifeng, Tang, Xiaoxuan, Liu, Yan, Liu, Mei, Yang, Liu, Yang, Yumin

“…Due to the complex spatial‐temporal pathophysiology of spinal cord injury (SCI), effective modulation of SCI‐specific inflammatory pathogenesis to achieve…”
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NFE2 Induces miR-423-5p to Promote Gluconeogenesis and Hyperglycemia by Repressing the Hepatic FAM3A-ATP-Akt Pathway by Yang, Weili, Wang, Junpei, Chen, Zhenzhen, Chen, Ji, Meng, Yuhong, Chen, Liming, Chang, Yongsheng, Geng, Bin, Sun, Libo, Dou, Lin, Li, Jian, Guan, Youfei, Cui, Qinghua, Yang, Jichun

“…Hepatic FAM3A expression is repressed under obese conditions, but the underlying mechanism remains unknown. This study determined the role and mechanism of…”
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Repurposing Doxepin to Ameliorate Steatosis and Hyperglycemia by Activating FAM3A Signaling Pathway by Chen, Zhenzhen, Liu, Xiangyang, Luo, Yanjin, Wang, Junpei, Meng, Yuhong, Sun, Lei, Chang, Yongsheng, Cui, Qinghua, Yang, Jichun

“…Mitochondrial protein FAM3A suppresses hepatic gluconeogenesis and lipogenesis. This study aimed to screen drug(s) that activates FAM3A expression and evaluate…”
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Deficiency of Kif15 gene inhibits tumor growth due to host CD8+T lymphocytes increase by Zhang, Siming, Tu, Qifeng, Qian, Xiaowei, Wang, Junpei, Ma, Chao, Yang, Liu, Liu, Yan, Wu, Ronghua, Liu, Mei

“…Kif15, also name kinesin-12, is a microtubule (MT) associate protein, which functions as a regulator of MT-dependent transport or spindle organization…”
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FAM3A maintains metabolic homeostasis by interacting with F1-ATP synthase to regulate the activity and assembly of ATP synthase by Yan, Han, Meng, Yuhong, Li, Xin, Xiang, Rui, Hou, Song, Wang, Junpei, Wang, Lin, Yu, Xiaoxing, Xu, Ming, Chi, Yujing, Yang, Jichun

“…Reduced mitochondrial ATP synthase (ATPS) capacity plays crucial roles in the pathogenesis of metabolic disorders. However, there is currently no effective…”
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Fidgetin impacts axonal growth and branching in a local mTOR signal dependent manner by Ma, Chao, Wang, Junpei, Tu, Qifeng, Wu, Ronghua, Lai, Xiaona, Lin, Ge, Dong, Zhangji, Guan, Tuchen, Qiang, Liang, Liu, Yan, Liu, Mei

“…Neurons require a constant increase in protein synthesis during axonal growth and regeneration. AKT-mTOR is a central pathway for mammalian cell survival and…”
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Kif15 deficiency contributes to depression-like behavior in mice by Wang, Junpei, Tu, Qifeng, Zhang, Siming, He, Xiaomei, Ma, Chao, Qian, Xiaowei, Wu, Ronghua, Shi, Xinyu, Yang, Zhangyi, Liu, Yan, Dong, Zhangji, Liu, Mei

“…Neuropsychiatric disorders have a high incidence worldwide. Kinesins, a family of microtubule-based molecular motor proteins, play essential roles in…”
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The DrugPattern tool for drug set enrichment analysis and its prediction for beneficial effects of oxLDL on type 2 diabetes by Huang, Chuanbo, Yang, Weili, Wang, Junpei, Zhou, Yuan, Geng, Bin, Kararigas, Georgios, Yang, Jichun, Cui, Qinghua

“…Enrichment analysis methods, e.g., gene set enrichment analysis, represent one class of important bioinformatical resources for mining patterns in biomedical…”
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FAM3B (PANDER) functions as a co‐activator of FOXO1 to promote gluconeogenesis in hepatocytes by Chi, Yujing, Meng, Yuhong, Wang, Junpei, Yang, Weili, Wu, Zhe, Li, Mei, Wang, Di, Gao, Fangfang, Geng, Bin, Tie, Lu, Zhang, Weiping, Yang, Jichun

“…FAM3B, also known as PANcreatic DERived factor (PANDER), promotes gluconeogenesis and lipogenesis in hepatocytes. However, the underlying mechanism(s) still…”
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