Search Results - "Wang, Jueqiong"

Mesenchymal stem cell-derived exosomal microRNA-367–3p alleviates experimental autoimmune encephalomyelitis via inhibition of microglial ferroptosis by targeting EZH2 by Fan, Jingyi, Han, Yusen, Sun, Huanhuan, Sun, Shichao, Wang, Ying, Guo, Ruoyi, Guo, Jiangyuan, Tian, Xinyi, Wang, Jinli, Wang, Jueqiong

“…Multiple sclerosis (MS) is an autoimmune, inflammatory demyelinating disorder of the central nervous system. Accumulating evidence has underscored the…”
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Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity by Wang, Jueqiong, Farkas, Carlos, Benyoucef, Aissa, Carmichael, Catherine, Haigh, Katharina, Wong, Nick, Huylebroeck, Danny, Stemmler, Marc P, Brabletz, Simone, Brabletz, Thomas, Nefzger, Christian M, Goossens, Steven, Berx, Geert, Polo, Jose M, Haigh, Jody J

“…The ZEB2 transcription factor has been demonstrated to play important roles in hematopoiesis and leukemic transformation. ZEB1 is a close family member of ZEB2…”
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ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms by Goossens, Steven, Wang, Jueqiong, Tremblay, Cedric S, De Medts, Jelle, T'Sas, Sara, Nguyen, Thao, Saw, Jesslyn, Haigh, Katharina, Curtis, David J, Van Vlierberghe, Pieter, Berx, Geert, Taghon, Tom, Haigh, Jody J

“…ZEB1 and ZEB2 are structurally related E-box binding homeobox transcription factors that induce epithelial to mesenchymal transitions during development and…”
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Increased peroxisome proliferator-activated receptor γ activity reduces imatinib uptake and efficacy in chronic myeloid leukemia mononuclear cells by Wang, Jueqiong, Lu, Liu, Kok, Chung H, Saunders, Verity A, Goyne, Jarrad M, Dang, Phuong, Leclercq, Tamara M, Hughes, Timothy P, White, Deborah L

“…Imatinib is actively transported by organic cation transporter-1 (OCT-1) influx transporter, and low OCT-1 activity in diagnostic chronic myeloid leukemia…”
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Pterostilbene Protects the Optic Nerves and Retina in a Murine Model of Experimental Autoimmune Encephalomyelitis via Activation of SIRT1 Signaling by Guo, Jiangyuan, Wang, Jueqiong, Guo, Ruoyi, Shao, Hongyuan, Guo, Li

“…•PT ameliorates the severity of EAE and delays EAE onset.•PT reduces the optic nerve and retinal inflammation in EAE mice.•PT protects the structure of the…”
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Exosomal miR-23b-3p from bone mesenchymal stem cells alleviates experimental autoimmune encephalomyelitis by inhibiting microglial pyroptosis by Wang, Jueqiong, Sun, Huanhuan, Guo, Ruoyi, Guo, Jiangyuan, Tian, Xinyi, Wang, Jinli, Sun, Shichao, Han, Yusen, Wang, Ying

“…Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system and is marked by inflammation and damage to the myelin sheath…”
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Mesenchymal stem cell-derived exosomal microRNA-367-3p mitigates lower limb ischemia/reperfusion injury in mouse skeletal muscle via EZH2 targeting by Sun, Huanhuan, Wang, Jueqiong, Bi, Wei, Zhang, Feng, Zhang, Kai, Tian, Xitao, Gao, Xiang, Zhang, Yanrong

“…This study aimed to investigate the protective effect of bone marrow mesenchymal stem cell-derived exosomes (BMSCs-exo) against lower limb ischemia/reperfusion…”
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Protective effect and mechanism of nicotinamide adenine dinucleotide against optic neuritis in mice with experimental autoimmune encephalomyelitis by Guo, Jiangyuan, Li, Bin, Wang, Jueqiong, Guo, Ruoyi, Tian, Ye, Song, Shuang, Guo, Li

“…•NAD+ intervention before the onset of EAE symptoms delayed signs of EAE.•NAD+ intervention alleviated EAE-induced inflammation in the optic nerve.•NAD+…”
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Extracellular vesicles containing miR-181a-5p as a novel therapy for experimental autoimmune encephalomyelitis-induced demyelination by Shi, Zhong, Sun, Huanhuan, Tian, Xinyi, Song, Xiujuan, Fan, Jingyi, Sun, Shichao, Wang, Jinli, Zhang, Jing, Wang, Jueqiong

“…[Display omitted] •MSC-derived EVs and miR-181a-5p alleviate MS symptoms in an animal model.•MSC-derived EVs and miR-181a-5p therapy reduces microglial…”
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The combined treatment of NAD+ and atorvastatin ameliorates the development of experimental autoimmune encephalomyelitis in C57BL/6 mice by Sun, Huanhuan, Wang, Jueqiong, Guo, Li, Wang, Ying, Zhang, Jing, Wang, Jinli, Quan, Moyuan, Li, Bin

“…Multiple sclerosis (MS) is a demyelinating and degenerating disorder of the central nervous system impacting many patients worldwide. Due to the complex…”
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Thorium Cluster Synthesized by a Solvent-Free Flux Approach: The Richest Coordination Diversity and Application Exploration by Zhou, Dan, Yang, Yang, Weng, Zhehui, Wang, Jueqiong, Yan, Yizhou, Cheng, Liwei, Fan, Yingtong, Chen, Lixi, Zhang, Hailong, Chen, Long, Wang, Yanlong, Wang, Shuao

“…The renaissance of research interests in actinide oxo clusters in the past decade arises from both the concerns of radioactive contamination and their…”
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Treatment with NAD+ inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice by Wang, Jueqiong, Zhao, Congying, Kong, Peng, Sun, Huanhuan, Sun, Zhe, Bian, Guanyun, Sun, Yafei, Guo, Li

“…Nicotinamide adenine dinucleotide (NAD+) plays vital roles in mitochondrial functions, cellular energy metabolism and calcium homeostasis. In this study, we…”
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Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway by Sun, Huanhuan, Wang, Jueqiong, Bi, Wei, Zhang, Feng, Chi, Kui, Shi, Long, Yuan, Tao, Ma, Kai, Gao, Xiang

“…Background. Limb ischemia/reperfusion (I/R) injury, as a life-threatening syndrome, is commonly caused by skeletal muscle damage resulting from oxidative…”
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Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response by Wang, Jueqiong, Zhao, Congying, Kong, Peng, Bian, Guanyun, Sun, Zhe, Sun, Yafei, Guo, Li, Li, Bin

“…Abstract Methylene blue (MB) is an effective neuroprotectant in many neurological disorders. AMP-activated protein kinase (AMPK)/silent mating-type information…”
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ZEB2 and LMO2 Drive Immature T-Cell Lymphoblastic Leukemia Via Distinct Oncogenic Mechanisms by Goossens, Steven, Wang, Jueqiong, Tremblay, Cedric, Van Vlierberghe, Pieter, Berx, Geert, Taghon, Tom, Haigh, Jody J

“…ZEB2, a E-box binding homeobox transcription factor, is able to induce epithelial-to-mesenchymal transition in the context of solid tumors. As such, its…”
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The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1 by Carmichael, Catherine L., Wang, Jueqiong, Nguyen, Thao, Kolawole, Oluseyi, Benyoucef, Aissa, De Mazière, Charlotte, Milne, Anna R., Samuel, Sona, Gillinder, Kevin, Hediyeh-zadeh, Soroor, Vo, Anh N.Q., Huang, Yizhou, Knezevic, Kathy, McInnes, William R.L., Shields, Benjamin J., Mitchell, Helen, Ritchie, Matthew E., Lammens, Tim, Lintermans, Beatrice, Van Vlierberghe, Pieter, Wong, Nicholas C., Haigh, Katharina, Thoms, Julie A.I., Toulmin, Emma, Curtis, David J., Oxley, Ethan P., Dickins, Ross A., Beck, Dominik, Perkins, Andrew, McCormack, Matthew P., Davis, Melissa J., Berx, Geert, Zuber, Johannes, Pimanda, John E., Kile, Benjamin T., Goossens, Steven, Haigh, Jody J.

“…Modulators of epithelial-to-mesenchymal transition (EMT) have recently emerged as novel players in the field of leukemia biology. The mechanisms by which EMT…”
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Modelling ponatinib resistance in tyrosine kinase inhibitor-naïve and dasatinib resistant BCR-ABL1 + cell lines by Lu, Liu, Kok, Chung Hoow, Saunders, Verity Ann, Wang, Jueqiong, McLean, Jennifer Anne, Hughes, Timothy Peter, White, Deborah Lee

“…TKI resistance remains a major impediment to successful treatment of CML. In this study, we investigated the emerging modes of ponatinib resistance in…”
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Necrostatin‑1 ameliorates the pathogenesis of experimental autoimmune encephalomyelitis by suppressing apoptosis and necroptosis of oligodendrocyte precursor cells by Wang, Ying, Guo, Li, Wang, Jueqiong, Shi, Wei, Xia, Zhilun, Li, Bin

“…Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by neuronal demyelination. MS pathogenesis occurs via multiple…”
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Dl-3-n-Butylphthalide (NBP) Mitigates Muscular Injury Induced by Limb Ischemia/Reperfusion in Mice through the HMGB1/TLR4/NF-κB Pathway by Sun, Huanhuan, Wang, Jueqiong, Bi, Wei, Zhang, Feng, Chi, Kui, Shi, Long, Li, Meng, Zhang, Jinwen, Zhang, Yanrong, Gao, Xiang

“…Objective. Limb ischemia/reperfusion (I/R) injury is a clinical syndrome associated with severe damages to skeletal muscles and other fatal outcomes. Oxidative…”
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NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway by Wang, Jinli, Song, Xueqin, Tan, Guojun, Sun, Pengtao, Guo, Li, Zhang, Ning, Wang, Jueqiong, Li, Bin

“…To investigate the effect of NAD+ on thymus autophagy in experimental autoimmune encephalomyelitis (EAE) mice through SIRT1. Bioinformatic analysis was used to…”
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