Search Results - "Wang, Jin Town"
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Identification of Biomarkers for Differentiation of Hypervirulent Klebsiella pneumoniae from Classical K. pneumoniae
Published in Journal of clinical microbiology (01-09-2018)“…A hypervirulent (hvKp) pathotype is undergoing global dissemination. In contrast to the usual health care-associated epidemiology of classical (cKp)…”
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Two T7-like Bacteriophages, K5-2 and K5-4, Each Encodes Two Capsule Depolymerases: Isolation and Functional Characterization
Published in Scientific reports (04-07-2017)“…Two Klebsiella bacteriophages K5-2 and K5-4, which are able to infect and grow on either capsular types K30/K69 and K5 or K8 and K5 of Klebsiella strains, were…”
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Isolation of a bacteriophage specific for a new capsular type of Klebsiella pneumoniae and characterization of its polysaccharide depolymerase
Published in PloS one (02-08-2013)“…Klebsiella pneumoniae is one of the major pathogens causing hospital-acquired multidrug-resistant infections. The capsular polysaccharide (CPS) is an important…”
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Klebsiella pneumoniae Type VI Secretion System Contributes to Bacterial Competition, Cell Invasion, Type-1 Fimbriae Expression, and In Vivo Colonization
Published in The Journal of infectious diseases (29-01-2019)“…Abstract Background We previously isolated a Klebsiella pneumoniae strain, NTUH-K2044, from a community-acquired pyogenic liver abscess (PLA) patient. Analysis…”
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Colistin resistance mechanisms in Klebsiella pneumoniae strains from Taiwan
Published in Antimicrobial agents and chemotherapy (01-05-2015)“…Colistin is one of the antibiotics of last resort for the treatment of carbapenem-resistant Klebsiella pneumoniae infection. This study showed that capsular…”
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Capsular types of Klebsiella pneumoniae revisited by wzc sequencing
Published in PloS one (09-12-2013)“…Capsule is an important virulence factor in bacteria. A total of 78 capsular types have been identified in Klebsiella pneumoniae. However, there are…”
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Isolation of genes involved in biofilm formation of a Klebsiella pneumoniae strain causing pyogenic liver abscess
Published in PloS one (12-08-2011)“…Community-acquired pyogenic liver abscess (PLA) complicated with meningitis and endophthalmitis caused by Klebsiella pneumoniae is an emerging infectious…”
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Identification of three capsule depolymerases in a bacteriophage infecting Klebsiella pneumoniae capsular types K7, K20, and K27 and therapeutic application
Published in Journal of biomedical science (20-05-2023)“…Klebsiella pneumoniae capsular types K1, K2, K5, K20, K54, and K57 are prevalent hypervirulent types associated with community infections, and worrisomely,…”
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9
Pyogenic liver abscess as endemic disease, Taiwan
Published in Emerging infectious diseases (01-10-2008)“…Pyogenic liver abscess has become a health problem in Taiwanese society. However, the extent of this problem has remained unclear because of the lack of a…”
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10
The role of Klebsiella pneumoniae rmpA in capsular polysaccharide synthesis and virulence revisited
Published in Microbiology (Society for General Microbiology) (01-12-2011)“…Klebsiella pneumoniae community-acquired pyogenic liver abscess (PLA) is an emerging infectious disease. The rmpA gene (for regulator of mucoid phenotype A)…”
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Aberrant Upregulation of Indoleamine 2,3-Dioxygenase 1 Promotes Proliferation and Metastasis of Hepatocellular Carcinoma Cells via Coordinated Activation of AhR and β-Catenin Signaling
Published in International journal of molecular sciences (28-10-2021)“…Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death worldwide. Chronic liver inflammation due to hepatitis virus infection…”
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12
Isolation of a Bacteriophage and Its Depolymerase Specific for K1 Capsule of Klebsiella pneumoniae: Implication in Typing and Treatment
Published in The Journal of infectious diseases (01-12-2014)“…Background. Klebsiella pneumoniae causing community-acquired pyogenic liver abscess complicated with metastatic meningitis and endophthalmitis has emerged…”
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Identification of three podoviruses infecting Klebsiella encoding capsule depolymerases that digest specific capsular types
Published in Microbial biotechnology (01-05-2019)“…Summary Klebsiella pneumoniae is an important human pathogen causing opportunistic nosocomial and community‐acquired infections. A major public health concern…”
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A Novel Role for the Klebsiella pneumoniae Sap (Sensitivity to Antimicrobial Peptides) Transporter in Intestinal Cell Interactions, Innate Immune Responses, Liver Abscess, and Virulence
Published in The Journal of infectious diseases (08-04-2019)“…Abstract Klebsiella pneumoniae is an important human pathogen causing hospital-acquired and community-acquired infections. Systemic K. pneumoniae infections…”
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15
Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases
Published in Frontiers in immunology (21-03-2022)“…is an important pathogen associated with nosocomial infection and has developed increasing resistance to antibiotics such as extended-spectrum β-lactams and…”
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Serum-Induced Iron-Acquisition Systems and TonB Contribute to Virulence in Klebsiella pneumoniae Causing Primary Pyogenic Liver Abscess
Published in The Journal of infectious diseases (15-06-2008)“…Background. Klebsiella pneumoniae has become the predominant pathogen causing primary pyogenic liver abscess (PLA). Methods. K. pneumoniae was stimulated by…”
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Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use
Published in Journal of biomedical science (07-02-2022)“…K1 capsular polysaccharide (CPS)-associated Klebsiella pneumoniae is the primary cause of pyogenic liver abscesses (PLA) in Asia. Patients with PLA often have…”
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Lipopolysaccharide O1 antigen contributes to the virulence in Klebsiella pneumoniae causing pyogenic liver abscess
Published in PloS one (12-03-2012)“…Klebsiella pneumoniae is the common cause of a global emerging infectious disease, community-acquired pyogenic liver abscess (PLA). Capsular polysaccharide…”
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Decolonization of carbapenem-resistant Klebsiella pneumoniae from the intestinal microbiota of model mice by phages targeting two surface structures
Published in Frontiers in microbiology (22-08-2022)“…BackgroundKlebsiella pneumoniae is a normal component of the human gastrointestinal tract microbiota. However, in some cases, it can cause disease. Over the…”
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A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications
Published in The Journal of experimental medicine (01-03-2004)“…Primary Klebsiella pneumoniae liver abscess complicated with metastatic meningitis or endophthalmitis is a globally emerging infectious disease. Its pathogenic…”
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