Search Results - "Wang, Jialiang S."
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Sclerostin and Osteocalcin: Candidate Bone-Produced Hormones
Published in Frontiers in endocrinology (Lausanne) (10-03-2021)“…In addition to its structural role, the skeleton serves as an endocrine organ that controls mineral metabolism and energy homeostasis. Three major cell types…”
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A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction
Published in Nature communications (01-07-2020)“…Osteocytes, cells ensconced within mineralized bone matrix, are the primary skeletal mechanosensors. Osteocytes sense mechanical cues by changes in fluid flow…”
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Pathways Controlling Formation and Maintenance of the Osteocyte Dendrite Network
Published in Current osteoporosis reports (01-12-2022)“…Purpose of Review The purpose of this review is to discuss the molecular mechanisms involved in osteocyte dendrite formation, summarize the similarities…”
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Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin
Published in Nature communications (01-11-2021)“…Some osteoblasts embed within bone matrix, change shape, and become dendrite-bearing osteocytes. The circuitry that drives dendrite formation during…”
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SP7: from Bone Development to Skeletal Disease
Published in Current osteoporosis reports (01-04-2023)“…Purpose of Review The purpose of this review is to summarize the different roles of the transcription factor SP7 in regulating bone formation and remodeling,…”
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Shared Enhancer Activity in the Limbs and Phallus and Functional Divergence of a Limb-Genital cis-Regulatory Element in Snakes
Published in Developmental cell (12-10-2015)“…The amniote phallus and limbs differ dramatically in their morphologies but share patterns of signaling and gene expression in early development. Thus far, the…”
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Selective reduction of visceral adipose tissue with injectable ice slurry
Published in Scientific reports (28-09-2023)“…Reduction in visceral adipose tissue (VAT) mass reduces body weight and metabolic disease risk in obese patients. However surgical removal of VAT is highly…”
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Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy
Published in iScience (16-09-2022)“…Glucocorticoid excess suppresses osteocyte remodeling of surrounding bone minerals, causes apoptosis of osteoblasts and osteocytes, and disrupts bone…”
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Role of histone deacetylases in bone development and skeletal disorders
Published in Bone (New York, N.Y.) (01-02-2021)“…Bone cells must constantly respond to hormonal and mechanical cues to change gene expression programs. Of the myriad of epigenomic mechanisms used by cells to…”
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PITX1 promotes chondrogenesis and myogenesis in mouse hindlimbs through conserved regulatory targets
Published in Developmental biology (01-02-2018)“…The PITX1 transcription factor is expressed during hindlimb development, where it plays a critical role in directing hindlimb growth and the specification of…”
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A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis
Published in The Journal of clinical investigation (01-05-2023)“…The renal actions of parathyroid hormone (PTH) promote 1,25-vitamin D generation; however, the signaling mechanisms that control PTH-dependent vitamin D…”
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Research on Prediction Method of Structural Seismic Response Based on Ensemble Learning
Published in Fangzai Jianzai Gongcheng Xuebao (01-01-2023)“…In order to obtain the displacement response of building structures in the earthquake process, and solve the delay problem in the active control of structures,…”
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Application of TightRope system combined with Locking-Loop biplane anatomical reconstruction technique for acute acromioclavicular joint dislocation
Published in Zhongguo xiu fu chong jian wai ke za zhi (15-03-2023)“…To investigate the effectiveness of TightRope system combined with Locking-Loop biplane anatomical reconstruction technique in the treatment of acute…”
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Effects of subcutaneous embedding of thumb-tack needle on tear film in patients with dry eye
Published in Zhōngguó zhēnjiǔ (12-03-2018)“…To observe the effects of subcutaneous embedding of thumb-tack needle combined with mytear and simple mytear on tear film in patients with dry eye. Eighty…”
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The effects of non-pharmacotherapy in decreasing the levels of serum lipid in patients with hyperlipidemia
Published in Zhōnghuá liúxíngbìng zázhì (01-04-2002)“…To develop a non-pharmacotherapy program for patients with hyperlipidemia and assess its effectiveness. A cluster control trial was used. The experimental…”
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Advance in immune microenvironment and immunotherapy in triplenegative breast cancer
Published in Zhongguo lin chuang yan jiu (01-10-2024)“…Breast cancer is the most common malignant tumor in women. Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, characterized…”
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Development and application of pneumatic-electric hybrid magnetic flux leakage detector for gas transmission pipelines
Published in You-qi chuyun (01-04-2024)“…[Objective] This paper focuses on developing a pneumatic-electric hybrid magnetic flux leakage(MFL) detector, examining and verifying its technical advantages…”
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