Search Results - "Wang, Honggen"

Rh[III]-Catalyzed Direct C–H Amination Using N-Chloroamines at Room Temperature by Grohmann, Christoph, Wang, Honggen, Glorius, Frank

“…An efficient Rh(III)-catalyzed direct C–H amination of N-pivaloyloxy benzamides with N-chloroamines proceeding at room temperature was achieved. The versatile…”
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Rh[III]-Catalyzed C–H Amidation Using Aroyloxycarbamates To Give N‑Boc Protected Arylamines by Grohmann, Christoph, Wang, Honggen, Glorius, Frank

“…The Rh(III)-catalyzed amidation of C(sp2)–H bonds by the use of electron-deficient aroyloxycarbamates as efficient electrophilic amidation partners is…”
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Palladium-Catalyzed Intramolecular C(sp2)–H Amidination by Isonitrile Insertion Provides Direct Access to 4-Aminoquinazolines from N-Arylamidines by Wang, Yong, Wang, Honggen, Peng, Jiangling, Zhu, Qiang

“…An efficient method for the synthesis of 4-amino-2-aryl(alkyl)quinazolines from readily available N-arylamidines and isonitriles via palladium-catalyzed…”
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Copper-Catalyzed Intramolecular Dehydrogenative Aminooxygenation: Direct Access to Formyl-Substituted Aromatic N-Heterocycles by Wang, Honggen, Wang, Yong, Liang, Dongdong, Liu, Lanying, Zhang, Jiancun, Zhu, Qiang

“…A direct synthesis of carbaldehydes through intramolecular dehydrogenative aminooxygenation has been developed. The process uses a catalytic amount of…”
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Manganese-mediated reductive functionalization of activated aliphatic acids and primary amines by Li, Zhan, Wang, Ke-Feng, Zhao, Xin, Ti, Huihui, Liu, Xu-Ge, Wang, Honggen

“…Alkyl carboxylic acids as well as primary amines are ubiquitous in all facets of biological science, pharmaceutical science, chemical science and materials…”
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(Pentamethylcyclopentadienyl)cobalt(III)‐Catalyzed Direct Trifluoromethylthiolation of Arenes via C−H Activation by Liu, Xu‐Ge, Li, Qingjiang, Wang, Honggen

“…The direct trifluoromethylthiolation of arenes was realized via (pentamethylcyclopentadienyl)cobalt(III)‐catalyzed C(sp2)‐H activation and coupling with AgSCF3…”
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Copper‐Catalyzed Stereoselective Defluorinative Borylation and Silylation of gem‐Difluoroalkenes by Tan, Dong‐Hang, Lin, E, Ji, Wei‐Wei, Zeng, Yao‐Fu, Fan, Wen‐Xin, Li, Qingjiang, Gao, Hui, Wang, Honggen

“…The copper‐catalyzed stereoselective defluorinative borylation and silylation of gem‐difluoroalkenes was developed. The protocol led to the exclusive formation…”
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Tandem Catalysis: Rh(III)-Catalyzed C–H Allylation/Pd(II)-Catalyzed N‑Allylation Toward the Synthesis of Vinyl-Substituted N‑Heterocycles by Zhang, Shang-Shi, Wu, Jia-Qiang, Liu, Xuge, Wang, Honggen

“…Tandem catalysis by Rh­(III)/Pd­(II) was realized, enabling rapid access to two important N-heterocycles that bear a synthetically valuable vinyl substituent…”
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N-Halosuccinimide enables cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides by Wu, Jun-Yunzi, Huang, Long-Ling, Fu, Jia-Luo, Li, Jia-Yi, Lin, Shuang, Yang, Shuang, Huang, Zhi-Shu, Wang, Honggen, Li, Qingjiang

“…Both the pyrroloindoline core and N –CF 3 moiety hold significant importance in medicinal chemistry. However, to date, no instances of constructing N –CF 3…”
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Rhodium(III)-catalyzed C-H/C-C activation sequence: vinylcyclopropanes as versatile synthons in direct C-H allylation reactions by Wu, Jia-Qiang, Qiu, Zhi-Ping, Zhang, Shang-Shi, Liu, Jing-Gong, Lao, Ye-Xing, Gu, Lian-Quan, Huang, Zhi-Shu, Li, Juan, Wang, Honggen

“…Succession of C-H activation and C-C activation was achieved by using a single rhodium(III) catalyst. Vinylcyclopropanes were used as versatile coupling…”
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Discovery of Novel 11-Triazole Substituted Benzofuro[3,2‑b]quinolone Derivatives as c‑myc G‑Quadruplex Specific Stabilizers via Click Chemistry by Zeng, De-Ying, Kuang, Guo-Tao, Wang, Shi-Ke, Peng, Wang, Lin, Shu-Ling, Zhang, Qi, Su, Xiao-Xuan, Hu, Ming-Hao, Wang, Honggen, Tan, Jia-Heng, Huang, Zhi-Shu, Gu, Lian-Quan, Ou, Tian-Miao

“…The specificity of nucleic acids’ binders is crucial for developing this kind of drug, especially for novel G-quadruplexes’ binders. Quindoline derivatives…”
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Rhodium-catalyzed formal [4 + 3] annulation reaction of N-methoxybenzamides with gem‑difluorocyclopropenes: A combination of experimental and theoretical studies by He, Yimiao, Tian, Limei, Chang, Xuexue, Qu, Zeming, Huang, Yanmin, Huang, Chusheng, Sun, Qing, Wang, Honggen

“…A rhodium-catalyzed [4 + 3] cycloaddition reaction between N-methoxybenzamides and gem‑difluorocyclopropenes is described. The reaction offers a mild and…”
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Synthesis of difluoromethylated benzylborons via rhodium(I)-catalyzed fluorine-retainable hydroboration of gem-difluoroalkenes by Cai, Yuanhong, Tan, Donghang, Zhang, Qiqi, Lv, Wenxin, Li, Qingjiang, Wang, Honggen

“…A rhodium-catalyzed hydroboration of aryl gem-difluoroalkenes leads to a regioselective construction of a series of α-difluoromethylated benzylborons. The use…”
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Et2Zn-promoted β-trans-selective hydroboration of ynamide by Wang, Kefeng, Zhuang, Zixi, Ti, Huihui, Wu, Peishan, Zhao, Xin, Wang, Honggen

“…The Et2Zn-promoted β-trans hydroboration of ynamides leads to a stereoselective construction of enamides bearing a valuable boryl substituent. Further…”
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NHC‐Au‐Catalyzed Isomerization of Propargylic B(MIDA)s to Allenes and Double Isomerization of Alkynes to 1,3‐Dienes by Liu, Li‐Cai, Lin, Shuang, Xu, Kangwei, Qian, Jiasheng, Wu, Ruibo, Li, Qingjiang, Wang, Honggen

“…The synthesis of allenyl boronates is an important yet challenging topic in organic synthesis. Reported herein is an NHC‐gold‐catalyzed 1,3‐H shift toward…”
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Catalytic, dearomative 2,3-difluorination of indoles by Tu, Fang-Hai, Lin, Shuang, Tang, Ya-Jie, Liu, Li-Cai, Li, Qingjiang, Wang, Honggen

“…Indolines, characterized by their diverse biological activities and structural significance, have garnered considerable attention in the realms of natural…”
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Regioselective Electrophilic Addition to Propargylic B(MIDA)s Enabled by β ‐Boron Effect by Li, Yin, Chen, Zhi‐Hao, Lin, Shuang, Liu, Yuan, Qian, Jiasheng, Li, Qingjiang, Huang, Zhi‐Shu, Wang, Honggen

“…Abstract Electrophilic addition reaction to alkynes is of fundamental importance in organic chemistry, yet the regiocontrol when reacting with unsymmetrical…”
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Brønsted Acid-Promoted Sequential Hydroarylation- Hydroamidation of Arene-Tethered 1-(2-Alkynylphenyl)ureas: Direct Access to 4,4-Spiro-3,4-dihydro-2-(1H)-quinazolinones by Wang, Honggen, Zhao, Jiaji, Zhang, Jiancun, Zhu, Qiang

“…A Brønsted acid‐promoted approach to 4,4‐sipro‐3,4‐dihydro‐2‐(1H)‐quinazolinones from arene‐tethered 1‐(2‐alkynylphenyl)ureas has been developed. The reaction…”
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Deaminative bromination, chlorination, and iodination of primary amines by Xue, Jiang-Hao, Li, Yin, Tan, Dong-Hang, Tu, Fang-Hai, Liu, Yuan, Li, Qingjiang, Wang, Honggen

“…The primary amino group has been seldom utilized as a transformable functionality in organic synthesis. Reported herein is a deaminative halogenation of…”
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p-Toluenesulfonic Acid Promoted Annulation of 2-Alkynylanilines with Activated Ketones: Efficient Synthesis of 4-Alkyl-2,3-Disubstituted Quinolines by Peng, Changlan, Wang, Yong, Liu, Lanying, Wang, Honggen, Zhao, Jiaji, Zhu, Qiang

“…Reactions between readily available 2‐alkynylanilines and activated ketones such as β‐keto esters promoted by p‐toluenesulfonic acid afford…”
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