Search Results - "Wang, Hechuan"

Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions by Ordonez, Alvaro A., Wang, Hechuan, Magombedze, Gesham, Ruiz-Bedoya, Camilo A., Srivastava, Shashikant, Chen, Allen, Tucker, Elizabeth W., Urbanowski, Michael E., Pieterse, Lisa, Fabian Cardozo, E., Lodge, Martin A., Shah, Maunank R., Holt, Daniel P., Mathews, William B., Dannals, Robert F., Gobburu, Jogarao V. S., Peloquin, Charles A., Rowe, Steven P., Gumbo, Tawanda, Ivaturi, Vijay D., Jain, Sanjay K.

“…Tuberculosis (TB) is the leading cause of death from a single infectious agent, requiring at least 6 months of multidrug treatment to achieve cure 1 . However,…”
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Porcine skeletal muscle typing in histochemical and in-situ RT-PCR analysis by Lin, Tao, Liu, Zhun, Dai, Fawen, Wang, Hechuan, Zuo, Jianjun

“…Currently, there are plenty of histochemical methods to classify pig muscle fibers, which confused the naming and classification of muscle fibers. This study…”
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Effect of Sox9 on TGF-β1-mediated atrial fibrosis by Wang, Hechuan, Chen, Yiqi, Zhao, Shuting, Wang, Xiaowen, Lu, Kai, Xiao, Hua

“…Abstract Atrial fibrosis is a crucial mechanism responsible for atrial fibrillation (AF). Sex-determining region Y-box containing gene 9 (Sox9) plays a pivotal…”
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Exogenous spermidine effectively improves the quality of cryopreserved boar sperm by Li, Jingchun, Wang, Hechuan, Guo, Minghui, Li, Tianfeng, Zhang, Han, Zhang, Qun, Wang, Qian, Song, Yulun, Feng, Heze, Wei, Guosheng

“…Boar sperm are less resistant to the dramatic environmental changes that occur during in vitro preservation. Spermidine has various physiological functions…”
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Methylprednisolone improves the quality of liquid preserved boar spermatozoa in vitro and reduces polymorphonuclear neutrophil chemotaxis and phagocytosis by Li, Yanbing, Wang, Hechuan, Wang, Shuo, Zhang, Qun, Zhang, Han, Li, Tianfeng, Wang, Qian, Guo, Minghui, Feng, Heze, Song, Yulun, Wei, Guosheng, Li, Jingchun

“…After artificial insemination, immune cells such as polymorphonuclear neutrophils will be recruited into the genital tract and induce endometrial inflammation,…”
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Combination of Exogenous Spermidine and Phosphocreatine Efficiently Improved the Quality and Antioxidant Capacity of Cryopreserved Boar Sperm and Reduced Apoptosis‐Like Changes by Li, Jingchun, Wang, Hechuan, Guo, Minghui, Guo, Qing, Li, Yanbing

“…ABSTRACT The low resistance of boar sperm to cryopreservation dictates that addition antioxidants and energetic substances to the diluent to improve sperm…”
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Co/Al LDH-based dual superlyophobic honeycomb-like surfaces for on-demand oil/water separation and dye degradation by Hou, Zhiqiang, Lv, Xinhui, Wang, Hechuan, Xie, Zhiyue, Zhu, Xiaotao, Liu, Mingming

“…Wastewater from industrial processes usually contains insoluble oil slick and soluble organic dyes. Thus, it is of great significance to design novel materials…”
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MG53/CAV1 regulates transforming growth factor-β1 signaling-induced atrial fibrosis in atrial fibrillation by Zhang, Meixia, Wang, Hechuan, Wang, Xiaowen, Bie, Mengjun, Lu, Kai, Xiao, Hua

“…Atrial fibrosis plays a significant role in the development of atrial fibrillation (AF). Previously, we showed that mitsugumin 53 (MG53) regulates TGF-β1…”
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Caveolin-1 Deficiency Induces Atrial Fibrosis and Increases Susceptibility to Atrial Fibrillation by the STAT3 Signaling Pathway by Zhang, Meixia, Wang, Hechuan, Bie, Mengjun, Wang, Xiaowen, Lu, Kai, Xiao, Hua

“…Atrial fibrillation (AF) is a common arrhythmia in the clinic. Ablation failure and recurrence after cardioversion have become medical problems worldwide. An…”
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Sheep litter size heredity basis using genome‐wide selective analysis by Cui, Weiguo, Wang, Hechuan, Li, Jingchun, Lv, Dongyu, Xu, Jiayi, Liu, Mengyu, Yin, Guoan

“…Sheep are important herbivorous domestic animal globally, and the Chinese indigenous sheep breed has a multitude of economically significant variations due to…”
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Diffusion in networks by cooperative particle filtering by Hechuan Wang, Djuric, Petar M.

“…In this paper, we propose a diffusion method for estimation of hidden processes by cooperative agents in a network. We adopt particle filtering for estimating…”
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On Importance Sampling with Applications to Signal Processing by Wang, Hechuan

“…Importance sampling (IS) is a powerful tool for Bayesian estimation. However, implementing IS can be very challenging. This is especially true in sampling from…”
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Pharmacometric Approaches to Precision Therapeutic Management for Antimicrobials by Wang, Hechuan

“…Antimicrobials have been widely used for decades in the treatment of various types of bacterial infections and their properties have been thoroughly…”
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Population Pharmacokinetic Modeling of Gentamicin in Pediatrics by Wang, Hechuan, Sherwin, Catherine, Gobburu, Jogarao V.S., Ivaturi, Vijay

“…The primary objective of this work was to characterize the pharmacokinetics (PK) of gentamicin across the whole pediatric age spectrum from premature neonates…”
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Phosphocreatine addition to extender enhances the quality and antioxidant capacity of cryopreserved boar sperm by Wang, Hechuan, Guo, Minghui, Li, Tianfeng, Zhang, Han, Wang, Qian, Zhang, Qun, Song, Yulun, Feng, Heze, Li, Yanbing, Wei, Guosheng, Li, Jingchun

“…Boar sperm are less resistant to drastic changes in the external environment during cryopreservation, mainly because their plasma membranes are rich in…”
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Adaptive Importance Sampling Via Auto-Regressive Generative Models and Gaussian Processes by Wang, Hechuan, Bugallo, Monica F., Djuric, Petar M.

“…The quality of importance distribution is vital to adaptive importance sampling, especially in high dimensional sampling spaces where the target distributions…”
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Population Pharmacokinetics of Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E‐Mutant Astrocytomas by Wang, Hechuan, Long‐Boyle, Janel, Winger, Beth Apsel, Nicolaides, Theodore, Mueller, Sabine, Prados, Michael, Ivaturi, Vijay

“…Vemurafenib (Zelboraf) is an orally available BRAFV600E inhibitor approved for the treatment of unresectable or metastatic BRAFV600E‐mutant melanoma. The…”
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Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) by Nicolaides, Theodore, Nazemi, Kellie J., Crawford, John, Kilburn, Lindsay, Minturn, Jane, Gajjar, Amar, Gauvain, Karen, Leary, Sarah, Dhall, Girish, Aboian, Mariam, Robinson, Giles, Long-Boyle, Janel, Wang, Hechuan, Molinaro, Annette M., Mueller, Sabine, Prados, Michael

“…Background: BRAFV600E mutation is present in a subset of pediatric brain tumors. Vemurafenib is an oral, selective ATP-competitive inhibitor of BRAFV600E…”
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THER-26. PHARMACOKINETIC AND UPDATED OUTCOME DATA FROM PNOC-002: A SAFETY STUDY OF VEMURAFENIB, AN ORAL INHIBITOR OF BRAFV600E, IN CHILDREN WITH RECURRENT/REFRACTORY BRAFV600E MUTANT BRAIN TUMORS by Nicolaides, Theodore, Margol, Ashley, Gajjar, Amar, Goldman, Stewart, Gauvain, Karen, Kilburn, Lindsay, Nazemi, Kellie, Minturn, Jane, Leary, Sarah, Whipple, Nicholas, Gururangan, Sridharan, Crawford, John, Long-Boyle, Janel, Wang, Hechuan, Ivaturi, Vijay, Aboian, Mariam, Molinaro, Annette, Mueller, Sabine, Prados, Michael

“…Abstract BACKGROUND: Vemurafenib is an orally administered inhibitor of BRAF-V600E kinase approved for the treatment of BRAF-V600E mutated melanoma. We have…”
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A Consideration of Fixed Dosing Versus Body Size‐Based Dosing Strategies for Chimeric Antigen Receptor T‐Cell Therapies by He, Jimmy Zhijian, Wang, Hechuan, Lim, KyoungSoo, Ren, Song, Rollins, Fred, Vallaster, Markus, Wong, Ryan, Stebbings, Richard, Standifer, Nathan, Keefe, Robert, Phipps, Alex, Gibbs, Megan

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