Search Results - "Wang, Haoxun"

Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway by Gong, Tianxiao, Cui, Liuqing, Wang, Haili, Wang, Haoxun, Han, Na

“…Hypoxia-mediated chemoresistance has been regarded as an important obstacle in the development of cancer treatment. Knockdown of krüppel-like factor 5 (KLF5)…”
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The activity of organic anion transporter-3: Role of dexamethasone by Wang, Haoxun, Liu, Chenchang, You, Guofeng

“…Human organic anion transporter-3 (hOAT3) is richly expressed in the kidney, where it plays critical roles in the secretion, from the blood to urine, of…”
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The SUMO-Specific Protease Senp2 Regulates SUMOylation, Expression and Function of Human Organic Anion Transporter 3 by Wang, Haoxun, You, Guofeng

“…Organic anion transporter 3 (OAT3) plays a vital role in removing a broad array of anionic drugs from kidney, thereby avoiding their possibly toxic side…”
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Regulation of organic anion transporters: Role in physiology, pathophysiology, and drug elimination by Zhang, Jinghui, Wang, Haoxun, Fan, Yunzhou, Yu, Zhou, You, Guofeng

“…The members of the organic anion transporter (OAT) family are mainly expressed in kidney, liver, placenta, intestine, and brain. These transporters play…”
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The regulation of human organic anion transporter 4 by insulin-like growth factor 1 and protein kinase B signaling by Yu, Zhou, Wang, Haoxun, You, Guofeng

“…[Display omitted] Human organic anion transporter 4 (hOAT4), mainly expressed in the kidney and placenta, is essential for the disposition of numerous drugs,…”
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SGK1/Nedd4–2 signaling pathway regulates the activity of human organic anion transporters 3 by Wang, Haoxun, You, Guofeng

“…Human organic anion transporter 3 (hOAT3) is localized at the basolateral membrane of renal proximal tubule cells and facilitates the renal secretion of…”
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Activation of Protein Kinase A Stimulates SUMOylation, Expression, and Transport Activity of Organic Anion Transporter 3 by Wang, Haoxun, Zhang, Jinghui, You, Guofeng

“…Organic anion transporter 3 (OAT3) plays a vital role in removing a broad variety of anionic drugs from kidney, thus avoiding their possible toxicity in the…”
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The mechanistic links between insulin and human organic anion transporter 4 by Wang, Haoxun, Zhang, Jinghui, You, Guofeng

“…[Display omitted] Human organic anion transporter 4 (hOAT4) belongs to a class of organic anion transporters that exert critical function in the secretion,…”
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An Essential Role of Nedd4‑2 in the Ubiquitination, Expression, and Function of Organic Anion Transporter‑3 by Xu, Da, Wang, Haoxun, You, Guofeng

“…Organic anion transporter-3 (OAT3) is a member of the organic anion transporter family that mediates the body disposition of a diverse array of clinically…”
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Inhibition of proteasome, but not lysosome, upregulates organic anion transporter 3 in vitro and in vivo by Fan, Yunzhou, Wang, Haoxun, Yu, Zhou, Liang, Zhengxuan, Li, Yufan, You, Guofeng

“…[Display omitted] Organic anion transporter 3 (OAT3), an indispensable basolateral membrane transporter predominantly distributed in the kidney proximal…”
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Posttranslational Regulation of Organic Anion Transporters by Ubiquitination: Known and Novel by Xu, Da, Wang, Haoxun, You, Guofeng

“…Organic anion transporters (OATs) encoded by solute carrier 22 family are localized in the epithelia of multiple organs, where they mediate the absorption,…”
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Nedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1 by Xu, Da, Wang, Haoxun, Zhang, Qiang, You, Guofeng

“…Human organic anion transporter 1 (hOAT1) expressed at the membrane of the kidney proximal tubule cells mediates the body disposition of a diverse array of…”
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Correlation of p16 and cyclin D1 expression with the incidence and prognosis of cardiac carcinoma by Wang, Haoxun, Wang, Jing, Zhao, Bingbo

“…Correlation of p16 and cyclin D1 expression with the incidence and prognosis of cardiac carcinoma was investigated. Thirty-six patients with cardiac carcinoma…”
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Post-translational Regulation of Organic Anion Transporters by Ubiquitination: Known and Novel by Xu, Da, Wang, Haoxun, You, Guofeng

“…Organic anion transporters (OATs) encoded by solute carrier 22 (SLC22) family are localized in the epithelia of multiple organs, where they mediate the…”
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Serum- and glucocorticoid-inducible kinase SGK2 regulates human organic anion transporters 4 via ubiquitin ligase Nedd4-2 by Wang, Haoxun, Xu, Da, Toh, May Fern, Pao, Alan C., You, Guofeng

“…Sgk2 stimulates hOAT4 transport activity by abrogating the inhibitory effect of Nedd4-2 on the transporter. [Display omitted] Human organic anion transporter 4…”
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Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1[alpha]-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway by Gong, Tianxiao, Cui, Liuqing, Wang, Haili, Wang, Haoxun, Han, Na

“…Background Hypoxia-mediated chemoresistance has been regarded as an important obstacle in the development of cancer treatment. Knockdown of krüppel-like factor…”
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Regulation of Renal Organic Anion Transporters by Wang, Haoxun

“…Organic anion transporters (OATs) are a group of membrane proteins that are mainly involved in the body disposition of organic anionic molecules or…”
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The role of Nedd4-1 WW domains in binding and regulating human organic anion transporter 1 by Xu, Da, Wang, Haoxun, Gardner, Carol, Pan, Zui, Zhang, Ping L, Zhang, Jinghui, You, Guofeng

“…Human organic anion transporter 1 (hOAT1), expressed at the basolateral membrane of kidney proximal tubule cells, mediates the active renal secretion of a…”
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Inhibitory effects of chemotherapeutics on human organic anion transporter hOAT4 by Toh, May Fern, Suh, Wonmo, Wang, Haoxun, Zhou, Peter, Hu, Longqin, You, Guofeng

“…Human organic anion transporter 4 (hOAT4) belongs to a family of organic anion transporters which play critical roles in the body disposition of clinically…”
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