Search Results - "Wang, Guangyun"

Schizandrin Protects against OGD/R-Induced Neuronal Injury by Suppressing Autophagy: Involvement of the AMPK/mTOR Pathway by Wang, Guangyun, Wang, Tiezheng, Zhang, Yuanyuan, Li, Fang, Yu, Boyang, Kou, Junping

“…The neuroprotective role of schizandrin (SA) in cerebral ischemia-reperfusion (I/R) was recently highlighted. However, whether SA plays a regulatory role on…”
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Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway by Cao, Guosheng, Jiang, Nan, Hu, Yang, Zhang, Yuanyuan, Wang, Guangyun, Yin, Mingzhu, Ma, Xiaonan, Zhou, Kecheng, Qi, Jin, Yu, Boyang, Kou, Junping

“…Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, has been shown to inhibit cerebral ischemic injury. However, its potential…”
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NMMHC IIA triggers neuronal autophagic cell death by promoting F-actin-dependent ATG9A trafficking in cerebral ischemia/reperfusion by Wang, Guangyun, Wang, Tiezheng, Hu, Yang, Wang, Jieman, Wang, Yan, Zhang, Yuanyuan, Li, Fang, Liu, Wentao, Sun, Yang, Yu, Boyang, Kou, Junping

“…Previous findings have shown that non-muscle myosin heavy-chain IIA (NMMHC IIA) is involved in autophagy induction triggered by starvation in D. melanogaster ;…”
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Ligustilide ameliorates hippocampal neuronal injury after cerebral ischemia reperfusion through activating PINK1/Parkin-dependent mitophagy by Mao, Zhiguo, Tian, Liyu, Liu, Jiao, Wu, Qian, Wang, Ning, Wang, Guangyun, Wang, Yang, Seto, Saiwang

“…Mitophagy plays a critical role in cerebral ischemia/reperfusion by timely removal of dysfunctional mitochondria. In mammals, PINK1/Parkin is the most classic…”
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Ligustilide attenuates ischemic stroke injury by promoting Drp1-mediated mitochondrial fission via activation of AMPK by Wu, Qian, Liu, Jiao, Mao, Zhiguo, Tian, Liyu, Wang, Ning, Wang, Guangyun, Wang, Yang, Seto, Saiwang

“…Ischemic stroke is a major global cause of death and permanent disability. Studies have suggested that mitochondria play a critical role in maintaining…”
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Chrysophanol exerts neuroprotective effects via interfering with endoplasmic reticulum stress apoptotic pathways in cell and animal models of Alzheimer's disease by Li, Xinquan, Cheng, Yaxun, Qin, Yunpeng, Gao, Huawu, Wang, Guangyun, Song, Hang, Wang, Yan, Cai, Biao

“…Chrysophanol (CHR), also well-known as Rhei radix et rhizome, is a crucial component in traditional Chinese medicine. It has been widely studied as a potential…”
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Tong-Qiao-Huo-Xue decoction activates PI3K/Akt/mTOR pathway to reduce BMECs autophagy after cerebral ischemia/reperfusion injury by Hua, Yaping, Zhai, Yan, Wang, Guangyun, Wang, Ning, Wu, Qian, Huang, Qi, Seto, Saiwang, Wang, Yan

“…Tong-Qiao-Huo-Xue Decoction (TQHXD) is a traditional classic Chinese Medicinal Formula (CMF) used for clinical treatment of ischemic stroke. TQHXD leads to…”
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Ginsenoside Rb1 reduced ischemic stroke-induced apoptosis through endoplasmic reticulum stress-associated IRE1/TRAF2/JNK pathway by Wei, Liangli, Yuan, Yuqi, Yang, Ziteng, Li, Yuqing, Wang, Tingting, Hu, Shenglin, Cai, Biao, Wang, Guangyun

“…The neuroprotective function of ginsenoside Rb1 (GRb1) in cerebral ischemia-reperfusion (I/R) was lately emphasized. However, whether GRb1 plays a regulatory…”
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Inhibition of ROS-NF-κB-dependent autophagy enhances Hypocrellin A united LED red light-induced apoptosis in squamous carcinoma A431 cells by Niu, Tianhui, Tian, Yan, Wang, Guangyun, Guo, Guangjin, Tong, Ying, Shi, Ying

“…Cutaneous squamous cell carcinoma (cSCC) is a type of malignant skin tumor derived from epidermal Malpighian cells. Photodynamic therapy is regarded as a…”
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Phosphorylation of MAP 1A regulates hyperphosphorylation of Tau in Alzheimer's disease model by Cai, Biao, Shao, Nan, Ye, Ting, Zhou, Peng, Si, Wenwen, Song, Hang, Wang, Guangyun, Kou, Junping

“…Background and purpose Hyperphosphorylation of Tau is one of the important pathological features of Alzheimer's disease (AD). Therefore, studying the…”
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Study on the mechanism of Tong-Qiao-Huo-Xue decoction regulating apoptosis via ASK1/MKK4/JNK pathway in MCAO/R rats by Yuan, Meiling, Zhang, Yun, Wang, Lei, Hua, Yaping, Wang, Yan, Cheng, Hui, Wang, Ning, Wang, Guangyun, Seto, Saiwang

“…Activation of blood stasis is a crucial aspect of stroke treatment, and the Tong-Qiao-Huo-Xue-Decoction (TQHXD) formula is commonly utilized for this purpose…”
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Tetramethylpyrazine Protects Against Oxygen-Glucose Deprivation-Induced Brain Microvascular Endothelial Cells Injury via Rho/Rho-kinase Signaling Pathway by Yang, Guang, Qian, Chen, Wang, Ning, Lin, Chenyu, Wang, Yan, Wang, Guangyun, Piao, Xinxin

“…Tetramethylpyrazine (TMP, also known as Ligustrazine), which is isolated from Chinese Herb Medicine Ligustium wollichii Franchat (Chuan Xiong), has been widely…”
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Ligustilide Ameliorates the Permeability of the Blood–Brain Barrier Model In Vitro During Oxygen–Glucose Deprivation Injury Through HIF/VEGF Pathway by Wu, Sipeng, Wang, Ning, Li, Jing, Wang, Guangyun, Seto, Sai Wang, Chang, Dennis, Liang, Huazheng

“…Chuanxiong rhizome has been widely used for the treatment of cerebral vascular disease in traditional Chinese medicine. The integrity of blood–brain barrier…”
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Pilot validation of on‐field STR typing and human identity testing by MinION nanopore sequencing by Luo, Yuan, Zhang, Jiarong, Ni, Ming, Mei, Zhusong, Ye, Qiao, Guo, Bingqian, Fang, Longmei, Feng, Dongyun, Wang, Lu, Yan, Jiangwei, Wang, Guangyun

“…Nanopore sequencing technology has broad application prospects in forensic medicine due to its small size, portability, fast speed, real‐time result analysis…”
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Front Cover: Pilot validation of on‐field STR typing and human identity testing by MinION nanopore sequencing by Luo, Yuan, Zhang, Jiarong, Ni, Ming, Mei, Zhusong, Ye, Qiao, Guo, Bingqian, Fang, Longmei, Feng, Dongyun, Wang, Lu, Yan, Jiangwei, Wang, Guangyun

“…DOI: 10.1002/elps.202300234 The cover picture shows nanopore sequencing platforms can be used to identify individuals in the field. Through scientific and…”
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Curcumin protects ANIT-induced cholestasis through signaling pathway of FXR-regulated bile acid and inflammation by Yang, Fan, Tang, Xiaowen, Ding, Lili, zhou, Yue, Yang, Qiaoling, Gong, Junting, Wang, Guangyun, Wang, Zhengtao, Yang, Li

“…Cholestasis is a clinically significant symptom and widely associated with liver diseases, however, there are very few effective therapies for cholestasis…”
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Waltonitone inhibits proliferation of hepatoma cells and tumorigenesis via FXR-miR-22-CCNA2 signaling pathway by Yang, Fan, Gong, Junting, Wang, Guangyun, Chen, Peng, Yang, Li, Wang, Zhengtao

“…Waltonitone (WA), an ursane-type pentacyclic triterpene extracted from Gentiana waltonii Burkill, was recently appeared to exert anti-tumor effect. However,…”
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Key Technologies of ARINC664 Bus Testing by Wang Guangyun, Yang Bo, Yang Qinghua

“…In this paper, a PXI-based avionics bus test system for ARINC 664 is developed using C# language and NI Measurement Studio. The system uses "Platform Invoke"…”
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Antifibrotic effects of Hypocrellin A combined with LED red light irradiation on keloid fibroblasts by counteracting the TGF-β/Smad/autophagy/apoptosis signalling pathway by Niu, Tianhui, Tian, Yan, Shi, Ying, Guo, Guangjin, Tong, Ying, Wang, Guangyun

“…•HA combined with red light irradiation treatment could suppress KFs hyperproliferation, collagen synthesis and ECM accumulation.•HA-R-PDT could regulate KFs…”
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YiQiFuMai lyophilized injection attenuates cerebral ischemic injury with inhibition of neuronal autophagy through intervention in the NMMHC IIA–actin–ATG9A interaction by Su, Linjie, Liu, Yining, Ma, Huifen, Zheng, Fan, Daia, Yujie, Wang, Tiezheng, Wang, Guangyun, Li, Fang, Zhang, Yuanyuan, Yu, Boyang, Gong, Shuaishuai, Kou, Junping

“…YiQiFuMai lyophilized injection (YQFM) is derived from a traditional Chinese medicine prescription termed Shengmai San.YQFM is clinically applied to the…”
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