Search Results - "Wang, Fangwu"

3070 – IDENTIFICATION OF NEW PHENOTYPES AND IN VITRO ASSAYS THAT CHARACTERIZE THE PROCESS OF HUMAN LYMPHOID LINEAGE SEPARATION FROM THE NEUTROPHIL/MONOCYTE LINEAGES by Gonzalez, Laura, Wang, Fangwu, Eaves, Connie

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Single-Cell Analysis of Human B Lymphoid and Neutrophil/Monocyte Lineage Restriction by Wang, Fangwu, Hammond, Colin, Eaves, Connie J.

“…Lifelong production of most types of mature blood cells is sustained by a small population of cells with extensive regenerative potential. However, the…”
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3039 – CLONAL TRACKING OF HUMAN B LYMPHOID AND NEUTROPHIL/MONOCYTE LINEAGE RESTRICTION by Wang, Fangwu, Eaves, Connie, Hammond, Colin

“…Human B lymphocytes (B) and neutrophils/monocytes (NM) are generated from a common hematopoietic B+NM progenitor, but the intervening cellular events and…”
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Sensitive and effective imaging of carbon monoxide in living systems with a near-infrared fluorescent probe by Xu, Zhencai, Song, Aibo, Wang, Fangwu, Chen, Hongwei

“…CO, a gas molecule that is harmful to living organisms, has a high affinity with hemoglobin, which will cause severe hypoxia. However, in recent years,…”
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Single-Cell Revelation of Extensive Heterogeneity in the Human Lymphocyte and Neutrophil/Monocyte Lineage Restriction Process Despite Highly Co-Regulated Changes in Cell Cycle Control by Wang, Fangwu, Gonzalez, Laura, Hirst, Martin, Simons, Benjamin D., Eaves, Connie J.

“…The production of mature blood lineages in humans has been viewed as a hierarchical process in which the primitive cells with multi-lineage potential generate…”
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3125 – IDENTIFICATION OF QUIESCENT HUMAN FETAL LIVER HEMATOPOIETIC STEM CELLS AND THEIR MAINTENANCE IN VITRO WITH FLT3-LIGAND by MacAldaz, Margarita, Wang, Fangwu, Wang, Keheng, Shu, Jeremy, Lau, Yasmine Yuen Man, Eaves, Connie

“…Identification of phenotypes of human hematopoietic cells that are highly enriched in those with long-term repopulating activity in immunodeficient mice has…”
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3013 – AGE-ASSOCIATED DIFFERENCES IN HUMAN HEMATOPOIETIC STEM CELL PROLIFERATION CONTROL REVEALED BY A NOVEL MULTIPARAMETER SINGLE-CELL ANALYSIS APPROACH by Hammond, Colin, Wang, Fangwu, Nakamichi, Naoto, Eaves, Connie

“…Throughout life, hematopoietic stem cells (HSCs) maintain production of short-lived mature blood cells by exiting a quiescent state and initiating…”
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3080 – HUMANIZED DRAGA MOUSE MODEL RECAPITULATES HUMAN T-CELL DIFFERENTIATION IN THE MOUSE THYMUS WITH HLA-MATCHED DONORS by Gonzalez, Laura, Wang, Fangwu, MacAldaz, Margarita, Wu, Vivian, Lau, Yasmine Yuen Man, Wang, Keheng, Knapp, David, Zandstra, Peter, Eaves, Connie

“…Differences between mice and humans, such as variations in the major histocompatibility complex (MHC) and variances in immune system function, pose challenges…”
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Aging alters the cell cycle control and mitogenic signaling responses of human hematopoietic stem cells by Hammond, Colin A., Wu, Si Wei, Wang, Fangwu, MacAldaz, Margarita E., Eaves, Connie J.

“…•Aging HSCs display a progressive and growth-factor sensitive elongation of G1.•Increased growth factor concentrations are required to stimulate mitogenesis in…”
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Development of an ultrafast fluorescent probe for specific recognition of hypochlorous acid and its application in live cells by Xu, Zhencai, Wang, Xiaofeng, Duan, Tingting, He, Rong, Wang, Fangwu, Zhou, Xuejun

“…Hypochlorous acid (HOCl), a highly potent oxidant of reactive oxygen species, plays critical roles in many physiological and pathological processes. In this…”
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Single-cell analysis identifies a CD33+ subset of human cord blood cells with high regenerative potential by Knapp, David J. H. F., Hammond, Colin A., Hui, Tony, van Loenhout, Marijn T. J., Wang, Fangwu, Aghaeepour, Nima, Miller, Paul H., Moksa, Michelle, Rabu, Gabrielle M., Beer, Philip A., Pellacani, Davide, Humphries, R. Keith, Hansen, Carl, Hirst, Martin, Eaves, Connie J.

“…Elucidation of the identity and diversity of mechanisms that sustain long-term human blood cell production remains an important challenge. Previous studies…”
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A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data by Knapp, David J.H.F., Hammond, Colin A., Wang, Fangwu, Aghaeepour, Nima, Miller, Paul H., Beer, Philip A., Pellacani, Davide, VanInsberghe, Michael, Hansen, Carl, Bendall, Sean C., Nolan, Garry P., Eaves, Connie J.

“…Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined models of human hematopoietic lineage…”
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Single-cell analysis identifies a CD33.sup.+ subset of human cord blood cells with high regenerative potential by Knapp, David J. H. F, Hammond, Colin A, Hui, Tony, van Loenhout, Marijn T. J, Wang, Fangwu, Aghaeepour, Nima, Miller, Paul H

“…Elucidation of the identity and diversity of mechanisms that sustain long-term human blood cell production remains an important challenge. Previous studies…”
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Carbody Structural Lightweighting Based on Implicit Parameterized Model by Chen, Xin, Ma, Fangwu, Wang, Dengfeng, Xie, Chen

“…Most of recent research on carbody lightweighting has focused on substitute material and new processing technologies rather than structures. However, new…”
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