Search Results - "Wang, Eddy Hsi Chun"

Pathomechanisms of immune-mediated alopecia by Anzai, Alessandra, Wang, Eddy Hsi Chun, Lee, Eunice Y, Aoki, Valeria, Christiano, Angela M

“…The hair follicle (HF) is a complex mini-organ that constantly undergoes dynamic cycles of growth and regression throughout life. While proper progression of…”
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Fibroblast cell-based therapy prevents induction of alopecia areata in an experimental model by Jalili, Reza B, Kilani, Ruhangiz T, Li, Yunyuan, Khosravi-maharlooie, Mohsen, Nabai, Layla, Wang, Eddy Hsi Chun, McElwee, Kevin J, Ghahary, Aziz

“…Alopecia areata (AA) is an autoimmune hair loss disease with infiltration of proinflammatory cells into hair follicles. Current therapeutic regimens are…”
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Functional interrogation of lymphocyte subsets in alopecia areata using single-cell RNA sequencing by Lee, Eunice Y, Dai, Zhenpeng, Jaiswal, Abhinav, Wang, Eddy Hsi Chun, Anandasabapathy, Niroshana, Christiano, Angela M

“…Alopecia areata (AA) is among the most prevalent autoimmune diseases, but the development of innovative therapeutic strategies has lagged due to an incomplete…”
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Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration by Chen, Chih-Lung, Huang, Wen-Yen, Wang, Eddy Hsi Chun, Tai, Kang-Yu, Lin, Sung-Jan

“…Stem cell activity is subject to non-cell-autonomous regulation from the local microenvironment, or niche. In adaption to varying physiological conditions and…”
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Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing by Shin, Jung U, Abaci, Hasan E., Herron, Lauren, Guo, Zongyou, Sallee, Brigitte, Pappalardo, Alberto, Jackow, Joanna, Wang, Eddy Hsi Chun, Doucet, Yanne, Christiano, Angela M.

“…Drug screening studies for inflammatory skin diseases are currently performed using model systems that only partially recapitulate human diseased skin. Here,…”
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Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata by Dai, Zhenpeng, Sezin, Tanya, Chang, Yuqian, Lee, Eunice Y, Wang, Eddy Hsi Chun, Christiano, Angela M

“…Alopecia areata (AA) is an autoimmune disease caused by T cell-mediated destruction of the hair follicle (HF). Therefore, approaches that effectively disrupt…”
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Increased CRHR1 expression on monocytes from patients with AA enables a pro‐inflammatory response to corticotrophin‐releasing hormone by Guo, Hong‐Wei, Lai, Hui‐Jun, Long, Bo‐Quan, Xu, Li‐Xin, Wang, Eddy Hsi Chun, Shapiro, Jerry, McElwee, Kevin J.

“…Stress may play a key role in alopecia areata (AA), though the exact interactions of stress with AA remain undefined. Corticotropin‐releasing hormone (CRH),…”
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The Development of Human Ex Vivo Models of Inflammatory Skin Conditions by Wang, Eddy Hsi Chun, Barresi-Thornton, Rebecca, Chen, Li-Chi, Senna, Maryanne Makredes, Liao, I-Chien, Chen, Ying, Zheng, Qian, Bouez, Charbel

“…Traditional research in inflammatory dermatoses has relied on animal models and reconstructed human epidermis to study these conditions. However, these models…”
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Blockade of IL-7 signaling suppresses inflammatory responses and reverses alopecia areata in C3H/HeJ mice by Dai, Zhenpeng, Wang, Eddy Hsi Chun, Petukhova, Lynn, Chang, Yuqian, Lee, Eunice Yoojin, Christiano, Angela M

“…The interleukin-7 (IL-7) signaling pathway plays an important role in regulation of T cell function and survival. We detected overexpression of IL-7 in…”
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Alopecia areata: Disease characteristics, clinical evaluation, and new perspectives on pathogenesis by Strazzulla, Lauren C, Wang, Eddy Hsi Chun, Avila, Lorena, Lo Sicco, Kristen, Brinster, Nooshin, Christiano, Angela M, Shapiro, Jerry

“…Alopecia areata (AA) is a common, inflammatory, nonscarring type of hair loss. Significant variations in the clinical presentation of AA have been observed,…”
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Alopecia areata: An appraisal of new treatment approaches and overview of current therapies by Strazzulla, Lauren C, Wang, Eddy Hsi Chun, Avila, Lorena, Lo Sicco, Kristen, Brinster, Nooshin, Christiano, Angela M, Shapiro, Jerry

“…Many therapies are available for the treatment of alopecia areata, including topical, systemic, and injectable modalities. However, these treatment methods…”
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42138 Effect of a novel witch hazel formula on skin barrier health by Liu, Xue, Goldberg, Jodi, Senna, Maryanne, Chun Wang, Eddy Hsi, Gosto, Sabina, Zheng, Qian

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CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata by Dai, Zhenpeng, Xing, Luzhou, Cerise, Jane, Wang, Eddy Hsi Chun, Jabbari, Ali, de Jong, Annemieke, Petukhova, Lynn, Christiano, Angela M, Clynes, Raphael

“…Alopecia areata (AA) is an autoimmune disease of the hair follicle that results in hair loss of varying severity. Recently, we showed that IFN-γ-producing…”
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49703 Unveiling the Therapeutic Potential: Investigating the Impact of a Novel Witch Hazel Formula on Anti-Inflammation and Antioxidation by Liu, Xue, Goldberg, Jodi, Senna, Maryanne, Hage, Tamer-Whittle, Chun Wang, Eddy Hsi, Liao, I-Chien, Gosto, Sabina, Cziryak, Paula, Chen, Ying, Zheng, Qian

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An open-label study evaluating the efficacy of abatacept in alopecia areata by Mackay-Wiggan, Julian, Sallee, Brigitte N., Wang, Eddy Hsi Chun, Sansaricq, Freda, Nguyen, Nhan, Kim, Carey, Chen, James C., Christiano, Angela M., Clynes, Raphael

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Alopecia areata by Strazzulla, Lauren C., Wang, Eddy Hsi Chun, Avila, Lorena, Lo Sicco, Kristen, Brinster, Nooshin, Christiano, Angela M., Shapiro, Jerry

“…Alopecia areata (AA) is a common, inflammatory, nonscarring type of hair loss. Significant variations in the clinical presentation of AA have been observed,…”
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Alopecia areata by Strazzulla, Lauren C., Wang, Eddy Hsi Chun, Avila, Lorena, Lo Sicco, Kristen, Brinster, Nooshin, Christiano, Angela M., Shapiro, Jerry

“…Many therapies are available for the treatment of alopecia areata, including topical, systemic, and injectable modalities. However, these treatment methods…”
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WITHDRAWN: Large-Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata by Lindestam Arlehamn, Cecilia S., Paul, Sinu, Wang, Eddy Hsi Chun, de Jong, Annemieke, Christiano, Angela M., Sette, Alessandro

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Large Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata by Lindestam Arlehamn, Cecilia S, Paul, Sinu, Wang, Eddy Hsi Chun, de Jong, Annemieke, Christiano, Angela M, Sette, Alessandro

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Alopecia Areata is Associated with Increased Expression of Heart Disease Biomarker Cardiac Troponin I by Wang, Eddy Hsi, Santos, Leopoldo, Li, Xi Yuan, Tran, Annie, Kim, Sandra S Y, Woo, Katrina, Shapiro, Jerry, McElwee, Kevin J

“…The development of androgenetic alopecia is associated with a risk of developing cardiovascular diseases, but the association of alopecia areata with…”
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