Search Results - "Wang, Doris D."
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Defining the role of GABA in cortical development
Published in The Journal of physiology (01-05-2009)“…Of the many signals in the developing nervous system, GABA (γ-aminobutyric acid) has been shown to be one of the earliest neurotransmitters present. Unlike in…”
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GABA Regulates Excitatory Synapse Formation in the Neocortex via NMDA Receptor Activation
Published in The Journal of neuroscience (21-05-2008)“…The development of a balance between excitatory and inhibitory synapses is a critical process in the generation and maturation of functional circuits…”
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Gap junction adhesion is necessary for radial migration in the neocortex
Published in Nature (London) (23-08-2007)“…Radial glia, the neuronal stem cells of the embryonic cerebral cortex, reside deep within the developing brain and extend radial fibres to the pial surface,…”
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Brain Network Oscillations During Gait in Parkinson’s Disease
Published in Frontiers in human neuroscience (23-10-2020)“…Human bipedal walking is a complex motor task that requires supraspinal control for balance and flexible coordination of timing and scaling of many muscles in…”
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Simultaneous cortical and subcortical recordings in humans with movement disorders: Acute and chronic paradigms
Published in NeuroImage (Orlando, Fla.) (15-08-2020)“…Invasive basal ganglia recordings in humans have significantly advanced our understanding of the neurophysiology of movement disorders. A recent technical…”
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Rates and predictors of long-term seizure freedom after frontal lobe epilepsy surgery: a systematic review and meta-analysis
Published in Journal of neurosurgery (01-05-2012)“…Frontal lobe epilepsy (FLE) is the second-most common focal epilepsy syndrome, and seizures are medically refractory in many patients. Although various studies…”
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Subthalamic local field potentials in Parkinson's disease and isolated dystonia: An evaluation of potential biomarkers
Published in Neurobiology of disease (01-05-2016)“…Abstract Local field potentials (LFP) recorded from the subthalamic nucleus in patients with Parkinson's disease (PD) demonstrate prominent oscillations in the…”
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Freezing of Gait in Parkinson's Disease: Invasive and Noninvasive Neuromodulation
Published in Neuromodulation (Malden, Mass.) (01-07-2021)“…Freezing of gait (FoG) is one of the most disabling yet poorly understood symptoms of Parkinson's disease (PD). FoG is an episodic gait pattern characterized…”
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Human upper extremity motor cortex activity shows distinct oscillatory signatures for stereotyped arm and leg movements
Published in Frontiers in human neuroscience (10-08-2023)“…Introduction Stepping and arm swing are stereotyped movements that require coordination across multiple muscle groups. It is not known whether the encoding of…”
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Epidural Spinal Electrogram Provides Direct Spinal Recordings in Awake Human Participants
Published in Frontiers in human neuroscience (26-10-2021)“…Little is known about the electrophysiological activity of the spinal cord during voluntary movement control in humans. We present a novel method for recording…”
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Comparison of Stereotactic Radiosurgery and Radiofrequency Ablation for Trigeminal Neuralgia in Multiple Sclerosis Patients
Published in Stereotactic and functional neurosurgery (01-12-2020)“…The optimal treatment for medically refractory trigeminal neuralgia in multiple sclerosis (MS-TN) patients is unknown. To compare treatment outcomes between…”
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Efficacy of vagus nerve stimulation in posttraumatic versus nontraumatic epilepsy
Published in Journal of neurosurgery (01-11-2012)“…In the US, approximately 500,000 individuals are hospitalized yearly for traumatic brain injury (TBI), and posttraumatic epilepsy (PTE) is a common sequela of…”
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Predictors of seizure freedom after surgery for malformations of cortical development
Published in Annals of neurology (01-07-2011)“…Objective: Malformations of cortical development (MCDs) are a major cause of medically refractory epilepsy. Our aim was to examine a surgical series of…”
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Anterior transposition of anomalous tortuous vertebral artery causing cervical radiculopathy – A report of 2 cases and review of literature
Published in World neurosurgery (01-05-2017)“…Abstract Background Cervical radiculopathy secondary to compression from vertebral artery (VA) tortuosity is a rare entity. Objective To describe successful…”
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Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo
Published in Epilepsy & behavior (01-07-2012)“…Abstract Introduction Increasing evidence suggests the role of inflammation in enhancing neuronal excitability and contributing to epileptogenesis…”
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The astrocyte odyssey
Published in Progress in neurobiology (11-12-2008)“…Neurons have long held the spotlight as the central players of the nervous system, but we must remember that we have equal numbers of astrocytes and neurons in…”
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Lesioning the Brain-From Serendipity to Science
Published in JAMA neurology (01-10-2024)Get more information
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Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson’s disease
Published in Nature biotechnology (01-09-2021)“…Neural recordings using invasive devices in humans can elucidate the circuits underlying brain disorders, but have so far been limited to short recordings from…”
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Unraveling the threads of stability: A review of the neurophysiology of postural control in Parkinson's disease
Published in Neurotherapeutics (01-04-2024)“…Postural instability is a detrimental and often treatment-refractory symptom of Parkinson's disease. While many existing studies quantify the biomechanical…”
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A Systematic Review Comparing Focused Ultrasound Surgery With Radiosurgery for Essential Tremor
Published in Neurosurgery (01-09-2023)“…Focused ultrasound (FUS-T) and stereotactic radiosurgery thalamotomy (SRS-T) targeting the ventral intermediate nucleus are effective incisionless surgeries…”
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