Search Results - "Wang, Donna H."

Knockout of Trpa1 accelerates age-related cardiac fibrosis and dysfunction by Ma, Shuangtao, Wang, Donna H

“…Age-related cardiac fibrosis contributes to the development of heart failure with preserved ejection fraction which lacks ideal treatment. Transient receptor…”
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Activation of TRPV1-Expressing Renal Sensory Nerves of Rats with N-Oleoyldopamine Attenuates High-Fat-Diet-Induced Impairment of Renal Function by Yu, Shuang-Quan, Ma, Shuangtao, Wang, Donna H

“…Enhanced renal sympathetic nerve activity (RSNA) contributes to obesity-induced renal disease, while the role of afferent renal nerve activity (ARNA) is not…”
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Genetic ablation of TRPV1 exacerbates pressure overload-induced cardiac hypertrophy by Zhong, Beihua, Rubinstein, Jack, Ma, Shuangtao, Wang, Donna H.

“…Transient receptor potential vanilloid 1 (TRPV1) channels expressed in sensory nerves may regulate vascular tone and cardiovascular function via their…”
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TRPV1 gene knockout impairs preconditioning protection against myocardial injury in isolated perfused hearts in mice by Zhong, Beihua, Wang, Donna H

“…Although the transient receptor potential vanilloid type 1 (TRPV1)-containing afferent nerve fibers are widely distributed in the heart, the relationship…”
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TRPV1 gene knockout impairs postischemic recovery in isolated perfused heart in mice by LIHONG WANG, WANG, Donna H

“…Although pharmacological studies suggest that the transient receptor potential vanilloid type 1 (TRPV1) channels expressed in sensory nerve fibers innervating…”
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Activation of TRPV1 Prevents Salt-Induced Kidney Damage and Hypertension After Renal Ischemia-Reperfusion Injury in Rats by Yu, Shuang-Quan, Ma, Shuangtao, Wang, Donna H.

“…Abstract Background/Aims: High-salt intake after recovery from renal ischemia-reperfusion (I/R) injury leads to hypertension with severe renal damage…”
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Selective ablation of TRPV1 by intrathecal injection of resiniferatoxin in rats increases renal sympathoexcitatory responses and salt sensitivity by Yu, Shuang-Quan, Ma, Shuangtao, Wang, Donna H

“…This study tested the hypothesis that selective ablation of transient receptor potential vanilloid type 1 (TRPV1)-positive nerve fibers by intrathecal…”
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TRPV1 Ablation Aggravates Inflammatory Responses and Organ Damage during Endotoxic Shock by Wang, Youping, Wang, Donna H

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Ablation of TRPV1-positive nerves exacerbates salt-induced hypertension and tissue injury in rats after renal ischemia-reperfusion via infiltration of macrophages by Yu, Shuang-Quan, Ma, Shuangtao, Wang, Donna H.

“…Background: High-salt intake after renal ischemia/reperfusion (I/R) injury leads to hypertension and further renal injury, but the mechanisms are largely…”
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Protective Effects of TRPV1 Activation Against Cardiac Ischemia/ Reperfusion Injury is Blunted by Diet-Induced Obesity by Zhong, Beihua, Ma, Shuangtao, Wang, Donna H

“…Activation of Transient Receptor Potential Vanilloid Subtype 1 (TRPV1) channels protects the heart from Ischemia/Reperfusion (I/R) injury through releasing…”
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N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1 by Zhong, Beihua, Wang, Donna H

“…N-oleoyldopamine (OLDA), a bioactive lipid originally found in the mammalian brain, is an endovanilloid that selectively activates the transient receptor…”
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Ablation of TRPV1 Abolishes Salicylate-Induced Sympathetic Activity Suppression and Exacerbates Salicylate-Induced Renal Dysfunction in Diet-Induced Obesity by Zhong, Beihua, Ma, Shuangtao, Wang, Donna H

“…Sodium salicylate (SA), a cyclooxygenase inhibitor, has been shown to increase insulin sensitivity and to suppress inflammation in obese patients and animal…”
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Protease-activated receptor 2-mediated protection of myocardial ischemia-reperfusion injury: role of transient receptor potential vanilloid receptors by Zhong, Beihua, Wang, Donna H

“…Activation of the protease-activated receptor 2 (PAR2) or the transient receptor potential vanilloid type 1 (TRPV1) channels expressed in cardiac sensory…”
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Role of the monocyte chemoattractant protein-1/C-C chemokine receptor 2 signaling pathway in transient receptor potential vanilloid type 1 ablation-induced renal injury in salt-sensitive hypertension by Wang, Youping, Zhu, Mingjun, Xu, Hui, Cui, Lin, Liu, Weihong, Wang, Xiaoxiao, Shen, Si, Wang, Donna H

“…Our recent studies indicate that the transient receptor potential vanilloid type 1 (TRPV1) channel may act as a potential regulator of monocyte/macrophage…”
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Ablation of TRPV1 Elevates Nocturnal Blood Pressure in Western Diet-fed Mice by Zhong, Beihua, Ma, Shuangtao, Wang, Donna H

“…This study tested the hypothesis that genetically ablation of transient receptor potential vanilloid type 1 (TRPV1) exacerbates impairment of baroreflex in…”
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Hypotension induced by activation of the transient receptor potential vanilloid 4 channels: role of Ca2+-activated K+ channels and sensory nerves by Gao, Feng, Wang, Donna H

“…OBJECTIVETo examine the mechanisms involved in hypotension induced by transient receptor potential vanilloid 4 (TRPV4) activation. METHODSWistar rats were…”
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TRPV1 protects renal ischemia-reperfusion injury in diet-induced obese mice by enhancing CGRP release and increasing renal blood flow by Zhong, Beihua, Ma, Shuangtao, Wang, Donna H

“…Obesity is a major risk factor for end-stage renal disease. Using transient receptor potential vanilloid 1 knockout (TRPV1 ) mice, we tested the hypothesis…”
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Role of the transient receptor potential vanilloid type 1 channel in renal inflammation induced by lipopolysaccharide in mice by Wang, Youping, Wang, Donna H

“…To determine the role of the transient receptor potential vanilloid type 1 (TRPV1) channel in the regulation of renal inflammation, lipopolysaccharide (LPS, 3…”
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Transient Receptor Potential Vanilloid Gene Deletion Exacerbates Inflammation and Atypical Cardiac Remodeling After Myocardial Infarction by Huang, Wei, Rubinstein, Jack, Prieto, Alejandro R, Thang, Loc Vinh, Wang, Donna H

“…The transient receptor potential vanilloid (TRPV1) channels expressed in sensory afferent fibers innervating the heart may be activated by protons or…”
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Knockout of Trpa1 Exacerbates Renal Ischemia–Reperfusion Injury With Classical Activation of Macrophages by Ma, Shuangtao, Wang, Donna H

“…Abstract BACKGROUND Classically activated macrophages contribute to the development of renal ischemia–reperfusion injury (IRI). This study aimed to investigate…”
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