Search Results - "Wang, Donglai"

Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode by Wang, Donglai, Kon, Ning, Lasso, Gorka, Jiang, Le, Leng, Wenchuan, Zhu, Wei-Guo, Qin, Jun, Honig, Barry, Gu, Wei

“…The acidic domain of SET binds and represses unacetylated p53, but this interaction is prevented by cellular-stress-induced p53 CTD acetylation. Acetylation in…”
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Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy by Yi, Jingjie, Tavana, Omid, Li, Huan, Wang, Donglai, Baer, Richard J., Gu, Wei

“…Since Mdm2 (Mouse double minute 2) inhibitors show serious toxicity in clinic studies, different approaches to achieve therapeutic reactivation of p53-mediated…”
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Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis by Xu, Wenbin, Yao, Han, Wu, Zhen, Yan, Xiaojun, Jiao, Zishan, Liu, Yajing, Zhang, Meng, Wang, Donglai

“…Metastasis is the major cause of lung cancer-related death, but the mechanisms governing lung tumor metastasis remain incompletely elucidated. SE translocation…”
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Fibroblast growth factor-2 promotes the function of tendon-derived stem cells in Achilles tendon restoration in an Achilles tendon injury rat model by Guo, Dongsheng, Li, Hui, Liu, Yubo, Yu, Xiao, Zhang, Xiangxin, Chu, Wenya, She, Yuanshi, Wang, Donglai, Chen, Guangxiang

“…The prognosis of Achilles tendon rupture is often unsatisfactory. Proliferative fibrous tissues and disordered collagen bundles make it difficult to guarantee…”
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Novel Distance Measures of q-Rung Orthopair Fuzzy Sets and Their Applications by Wang, Donglai, Yuan, Yige, Liu, Zhe, Zhu, Sijia, Sun, Zhifang

“…The q-rung orthopair fuzzy sets (q-ROFSs), a novel concept for processing vague information, offer a more potent and all-encompassing method compared to…”
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A comparative study between two methods of delivery of chemotherapeutic agent in patients with bone and soft tissue sarcoma of lower extremity by Shan, Jing, Lv, Sumei, Li, Haihong, Wang, Donglai, Zhang, Xiaoyu, Liu, Wei

“…We aimed to compare the effects of peripherally inserted central catheters (PICC) and implantable venous access devices (TIVADs) in terms of complications and…”
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Elementary Function-Based Fermatean Fuzzy Similarity Measures: Applications to Medical Pattern Recognition and Multi-Criteria Decision-Making by Liu, Zhe, Wang, Donglai, Letchmunan, Sukumar, Aljohani, Sarah, Mlaiki, Nabil

“…Fermatean fuzzy sets (FFSs) constitute a formidable tool for tackling uncertainty in information, thereby enjoying widespread adoption across multiple domains…”
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Alternatively mechanistic insights into acetylation in p53-mediated transcriptional regulation of cancer cell-intrinsic PD-1 by Wen, Jia, Yao, Han, Cao, Zhijie, Wang, Donglai

“…Since the recent discovery of cancer cell-intrinsic programmed cell death protein-1 (PD-1), the mechanisms that manipulate PD-1 functions in tumor development…”
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FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway by Zhou, Jingyi, Liao, Wenjuan, Yang, Jing, Ma, Ke, Li, Xue, Wang, Yachen, Wang, Donglai, Wang, Lina, Zhang, Yu, Yin, Yuxin, Zhao, Ying, Zhu, Wei-Guo

“…Forkhead box O (FOXO) transcriptional protein family members, including FOXO1 and FOXO3, are involved in the modulation of autophagy. However, whether there is…”
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Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2 by Wu, Zhen, Cao, Zhijie, Yao, Han, Yan, Xiaojun, Xu, Wenbin, Zhang, Mi, Jiao, Zishan, Zhang, Zijing, Chen, Jianyuan, Liu, Yajing, Zhang, Meng, Wang, Donglai

“…Posttranslational modifications represent a key step in modulating programmed death-1 (PD-1) functions, but the underlying mechanisms remain incompletely…”
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3-D Electric Field Computation of Steeple Rooftop Houses Near HVDC Transmission Lines by Wang, Donglai, Lu, Tiebing, Li, Qinyuan, Chen, Bo, Li, Xuebao

“…The existence of residential houses will distort the ion flow field under high-voltage direct current transmission lines. High efficiency electric field…”
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A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression by Zhang, Ling, Zhang, Jun, Xuan, Xiaofeng, Wu, Di, Yu, Jianfeng, Wang, Peizhen, Yang, Xiaomei, Zhang, Jieru, Gan, Wenjuan, He, Mengfan, Liu, Xiao-Min, Zhou, Jun, Wang, Donglai, Gu, Wei, Li, Dawei

“…The p53 tumor suppressor exerts antitumor functions through its ability to regulate the transcription of its downstream targets. Long noncoding RNAs (lncRNAs)…”
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Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability by Wang, Donglai, Zhou, Jingyi, Liu, Xiangyu, Lu, Danyu, Shen, Changchun, Du, Yipeng, Wei, Fu-Zheng, Song, Boyan, Lu, Xiaopeng, Yu, Yu, Wang, Lina, Zhao, Ying, Wang, Haiying, Yang, Yang, Akiyama, Yoshimitsu, Zhang, Hongquan, Zhu, Wei-Guo

“…Suppressor of variegation 3-9 homolog 1 (SUV39H1), a histone methyltransferase, catalyzes historie 3 lysine 9 trimethylation and is involved in heterochromatin…”
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Research on capacity optimization and real-time control of island microgrid considering time-shifting load by Wang, Wei, Wang, Donglai, Zhao, Yan, Yu, Yuan, Wang, Yuri

“…The utilization efficiency of renewable energy can be improved by the effective control of time-shifting load. In this paper, the characteristics of the…”
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Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1) by Liu, Xiangyu, Wang, Donglai, Zhao, Ying, Tu, Bo, Zheng, Zhixing, Wang, Lina, Wang, Haiying, Gu, Wei, Roeder, Robert G, Zhu, Wei-Guo

“…Numerous studies indicate that Sirtuin 1 (SIRT1), a mammalian nicotinamide adenine dinucleotide (NAD⁺)-dependent histone deacetylase (HDAC), plays a crucial…”
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Hollow village detection method based on non-intrusive power load monitoring by Liu, Rui, Wang, Donglai, Chen, Yan, Guo, Rui, Shi, Jiaqi

“…With the development of urbanization, the population and resources converge to the city, leading to different degrees of hollow village phenomenon in rural…”
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An unexpected role for p53 in regulating cancer cell-intrinsic PD-1 by acetylation by Cao, Zhijie, Kon, Ning, Liu, Yajing, Xu, Wenbin, Wen, Jia, Yao, Han, Zhang, Mi, Wu, Zhen, Yan, Xiaojun, Zhu, Wei-Guo, Gu, Wei, Wang, Donglai

“…Cancer cell-intrinsic programmed cell death protein-1 (PD-1) has emerged as a tumor regulator in an immunity-independent manner, but its precise role in…”
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The "readers" of unacetylated p53 represent a new class of acidic domain proteins by Wang, Donglai, Kon, Ning, Tavana, Omid, Gu, Wei

“…Acetylation of non-histone proteins plays important roles in regulating protein functions but the mechanisms of action are poorly understood. Our recent study…”
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SGSM2 inhibits thyroid cancer progression by activating RAP1 and enhancing competitive RAS inhibition by Su, Xi, Chen, Dong, Zhu, Lizhang, Jia, Hao, Cai, Jiaxuan, Li, Peng, Han, Bin, Wang, Donglai, Li, Hongtao, Fan, Jiaqian, Gu, Mengwei, Zhou, Yaqi, Guan, Haixia, Wei, Wei

“…Thyroid cancer (TC) is one of the most common malignancies involving the head and neck, and its incidences are increasing every year. Small G protein signaling…”
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The Role of Transcriptional Factor Brachyury on Cell Cycle Regulation in Non-small Cell Lung Cancer by Xu, Jingyi, Chen, Ming, Wu, Yinghui, Zhang, Hong, Zhou, Jundong, Wang, Donglai, Zou, Tianming, Shen, Jun

“…Lung cancer is the leading cause of cancer-related death, and non-small cell lung cancer (NSCLC) accounts for almost 80–85% of all lung cancer cases. The…”
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