Search Results - "Wang, Dong‐Xin"
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Perioperative neurocognitive disorders: A narrative review focusing on diagnosis, prevention, and treatment
Published in CNS neuroscience & therapeutics (01-08-2022)“…Perioperative neurocognitive disorders (NCDs) refer to neurocognitive abnormalities detected during the perioperative periods, including preexisting cognitive…”
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Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial
Published in The Lancet (British edition) (15-10-2016)“…Summary Background Delirium is a postoperative complication that occurs frequently in patients older than 65 years, and presages adverse outcomes. We…”
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Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis
Published in Cell death & disease (18-02-2019)“…Sepsis is life-threatening and often leads to acute brain damage. Dexmedetomidine, an α 2 -adrenoceptor agonist, has been reported to possess neuroprotective…”
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Impact of dexmedetomidine on the incidence of delirium in elderly patients after cardiac surgery: A randomized controlled trial
Published in PloS one (09-02-2017)“…Delirium is a frequent complication after cardiac surgery and its occurrence is associated with poor outcomes. The purpose of this study was to investigate the…”
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Worldwide Survey of the “Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium Monitoring/Management, Early Exercise/Mobility, and Family Empowerment” (ABCDEF) Bundle
Published in Critical care medicine (01-11-2017)“…To assess the knowledge and use of the Assessment, prevention, and management of pain; spontaneous awakening and breathing trials; Choice of analgesia and…”
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Erector spinae plane block versus quadratus lumborum block for postoperative analgesia after laparoscopic nephrectomy: A randomized controlled trial
Published in Journal of clinical anesthesia (01-09-2024)“…We compared the analgesic effects of erector spinae plane block versus quadratus lumborum block following laparoscopic nephrectomy. A randomized controlled…”
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Impact of Dexmedetomidine on Long-term Outcomes After Noncardiac Surgery in Elderly: 3-Year Follow-up of a Randomized Controlled Trial
Published in Annals of surgery (01-08-2019)“…OBJECTIVES:The aim was to compare the long-term outcomes of low-dose dexmedetomidine versus placebo in a randomized controlled trial (ChiCTR-TRC-10000802)…”
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Effects of dexmedetomidine as a perineural adjuvant for femoral nerve block: A systematic review and meta-analysis
Published in PloS one (19-10-2020)“…Femoral nerve block (FNB) is one of the first-line analgesic methods for patients following lower extremity surgery. However, FNB with local anesthetics alone…”
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Combined epidural-general anesthesia was associated with lower risk of postoperative complications in patients undergoing open abdominal surgery for pheochromocytoma: A retrospective cohort study
Published in PloS one (21-02-2018)“…Current evidences show that regional anesthesia is associated with decreased risk of complications after major surgery. However, the effects of combined…”
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Epidural morphine improves postoperative analgesia in patients after total knee arthroplasty: A randomized controlled trial
Published in PloS one (01-07-2019)“…Patients after total knee arthroplasty (TKA) often develop moderate to severe pain. This study compared the analgesic effect of low-dose epidural morphine vs…”
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Dynamic variables to predict fluid responsiveness in young children
Published in Pediatrics international (01-01-2023)“…Background The evidence that dynamic variables predict fluid responsiveness in young children is limited by conflicting research results. Methods Sixty…”
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Delirium in Older Patients after Combined Epidural–General Anesthesia or General Anesthesia for Major Surgery: A Randomized Trial
Published in Anesthesiology (Philadelphia) (01-08-2021)“…Delirium is a common and serious postoperative complication, especially in the elderly. Epidural anesthesia may reduce delirium by improving analgesia,…”
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Prevalence and risk factors of myocardial and acute kidney injury following radical nephrectomy with vena cava thrombectomy: a retrospective cohort study
Published in BMC anesthesiology (12-10-2021)“…Radical nephrectomy with thrombectomy is the mainstay treatment for patients with renal cell carcinoma with vena cava thrombus. But the procedure is full of…”
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Acetaminophen attenuates lipopolysaccharide-induced cognitive impairment through antioxidant activity
Published in Journal of neuroinflammation (21-01-2017)“…Considerable evidence has shown that neuroinflammation and oxidative stress play an important role in the pathophysiology of postoperative cognitive…”
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Noninvasive Measurement of Carbon Dioxide during One-Lung Ventilation with Low Tidal Volume for Two Hours: End-Tidal versus Transcutaneous Techniques
Published in PloS one (14-10-2015)“…There may be significant difference between measurement of end-tidal carbon dioxide partial pressure (PetCO2) and arterial carbon dioxide partial pressure…”
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Potential impact of epidural labor analgesia on the outcomes of neonates and children
Published in Chinese medical journal (05-10-2020)“…This review summarizes recent evidences regarding the potential influences of epidural labor analgesia (ELA) on the outcomes of neonates and children. Terms…”
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Early predictive factors of progression from severe type to critical ill type in patients with Coronavirus Disease 2019: A retrospective cohort study
Published in PloS one (02-12-2020)“…The current worldwide pandemic of Coronavirus Disease 2019 (COVID-19) has posed a serious threat to global public health, and the mortality rate of critical…”
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Emergence delirium is associated with increased postoperative delirium in elderly: a prospective observational study
Published in Journal of anesthesia (01-10-2020)“…Background The clinical significance of emergence delirium remains unclear. The purpose of this study was to investigate the association between emergence…”
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Appropriate Source Control and Antifungal Therapy are Associated with Improved Survival in Critically Ill Surgical Patients with Intra-abdominal Candidiasis
Published in World journal of surgery (01-05-2020)“…Background Intra-abdominal candidiasis (IAC) is the predominant type of invasive candidiasis with high mortality in surgical intensive care patients. The…”
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Impact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled trial
Published in BMC anesthesiology (13-09-2021)“…Dexmedetomidine promotes normal sleep architecture; the drug also improves analgesia. We therefore tested the hypothesis that supplementing intravenous…”
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