Search Results - "Wang, Congzhou"
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Conducting polymer-silk biocomposites for flexible and biodegradable electrochemical sensors
Published in Biosensors & bioelectronics (15-07-2016)“…Approaches to form flexible biosensors require strategies to tune materials for various biomedical applications. We report a facile approach using…”
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Silk Protein Lithography as a Route to Fabricate Sericin Microarchitectures
Published in Advanced materials (Weinheim) (09-07-2014)“…Photolithographic fabrication via a “silk sericin photoresist” is used to form precise protein microstructures directly and rapidly on a variety of substrates…”
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3
Metal–Organic Framework Encapsulation for Biospecimen Preservation
Published in Chemistry of materials (27-02-2018)“…Handling, transport, and storage of biospecimens such as blood and urine without refrigeration are extremely challenging. This formidable challenge leads to an…”
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4
Enhancing Protein Expression in HEK-293 Cells by Lowering Culture Temperature
Published in PloS one (20-04-2015)“…Animal cells and cell lines, such as HEK-293 cells, are commonly cultured at 37°C. These cells are often used to express recombinant proteins. Having a higher…”
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5
Spatial recognition and mapping of proteins using DNA aptamers
Published in Nanotechnology (14-11-2014)“…Atomic force microscopy-based adhesion force measurements have emerged as a powerful tool for the biophysical analyses of biological systems. Such measurements…”
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6
Single Molecule Force Spectroscopy to Compare Natural versus Artificial Antibody–Antigen Interaction
Published in Small (Weinheim an der Bergstrasse, Germany) (01-05-2017)“…Biorecognition is central to various biological processes and finds numerous applications in virtually all areas of chemistry, biology, and medicine…”
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7
Add-on plasmonic patch as a universal fluorescence enhancer
Published in Light, science & applications (04-07-2018)“…Fluorescence-based techniques are the cornerstone of modern biomedical optics, with applications ranging from bioimaging at various scales (organelle to…”
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Real-Time Observation of Antimicrobial Polycation Effects on Escherichia coli: Adapting the Carpet Model for Membrane Disruption to Quaternary Copolyoxetanes
Published in Langmuir (29-03-2016)“…Real-time atomic force microscopy (AFM) was used for analyzing effects of the antimicrobial polycation copolyoxetane P[(C12)-(ME2Ox)-50/50], C12–50 on the…”
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9
Potent and Selective Inhibition of the Open-Channel Conformation of AMPA Receptors by an RNA Aptamer
Published in Biochemistry (Easton) (13-07-2010)“…Inhibitors of AMPA receptors are useful as biochemical probes for structure−function studies and as drug candidates for a number of neurological disorders and…”
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Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: Consequences of Adding an N-3 Methylcarbamoyl Group to the Diazepine Ring of 2,3-Benzodiazepine Derivatives
Published in Biochemistry (Easton) (23-08-2011)“…2,3-Benzodiazepine derivatives are AMPA receptor inhibitors, and they are potential drugs for treating some neurological diseases caused by excessive activity…”
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Mechanism and Site of Inhibition of AMPA Receptors: Substitution of One and Two Methyl Groups at the 4‑Aminophenyl Ring of 2,3-Benzodiazepine and Implications in the “E” Site
Published in ACS chemical neuroscience (19-08-2015)“…2,3-Benzodiazepines are a well-known group of compounds for their potential antagonism against AMPA receptors. It has been previously reported that the…”
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Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: The Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives
Published in ACS chemical neuroscience (12-05-2011)“…2,3-Benzodiazepine derivatives are synthesized as drug candidates for the potential treatment of various neurodegenerative diseases involving the excessive…”
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13
Photothermal Attenuation of Cancer Cell Stemness, Chemoresistance, and Migration Using CD44-Targeted MoS2 Nanosheets
Published in Nano letters (08-03-2023)“…Cancer stem-like cells (CSCs) play key roles in chemoresistance, tumor metastasis, and clinical relapse. However, current CSC inhibitors lack specificity,…”
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Reversing the Epithelial–Mesenchymal Transition in Metastatic Cancer Cells Using CD146-Targeted Black Phosphorus Nanosheets and a Mild Photothermal Treatment
Published in ACS nano (22-02-2022)“…Cancer metastasis leads to most deaths in cancer patients, and the epithelial–mesenchymal transition (EMT) is the key mechanism that endows the cancer cells…”
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Photothermal Attenuation of Cancer Cell Stemness, Chemoresistance, and Migration Using CD44-Targeted MoS 2 Nanosheets
Published in Nano letters (08-03-2023)“…Cancer stem-like cells (CSCs) play key roles in chemoresistance, tumor metastasis, and clinical relapse. However, current CSC inhibitors lack specificity,…”
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Transmembrane MUC18 Targeted Polydopamine Nanoparticles and a Mild Photothermal Effect Synergistically Disrupt Actin Cytoskeleton and Migration of Cancer Cells
Published in Nano letters (24-11-2021)“…Transmembrane MUC18 is highly expressed on most metastatic cancers. Herein, we demonstrate that targeting MUC18 with polydopamine nanoparticles (PDA NPs) and a…”
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Stabilization of surface-bound antibodies for ELISA based on a reversable zeolitic imidazolate framework-8 coating
Published in Journal of colloid and interface science (15-04-2021)“…[Display omitted] Immunoassays typically must be stored under refrigerated conditions because antibodies, after being immobilized to solid surfaces, tend to…”
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Metal–Organic Framework Preserves the Biorecognition of Antibodies on Nanoscale Surfaces Validated by Single-Molecule Force Spectroscopy
Published in ACS applied materials & interfaces (15-01-2020)“…Antibody biorecognition forms the basis for numerous biomedical applications such as diagnostic assays, targeted drug delivery, and targeted cancer imaging…”
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N‑Cadherin Targeted Melanin Nanoparticles Reverse the Endothelial–Mesenchymal Transition in Vascular Endothelial Cells to Potentially Slow the Progression of Atherosclerosis and Cancer
Published in ACS nano (19-03-2024)“…Endothelial–mesenchymal transition (EndoMT) of vascular endothelial cells has recently been considered as a key player in the early progression of a variety of…”
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“Non-cytotoxic” doses of metal-organic framework nanoparticles increase endothelial permeability by inducing actin reorganization
Published in Journal of colloid and interface science (15-03-2023)“…[Display omitted] Cytotoxicity of nanoparticles is routinely characterized by biochemical assays such as cell viability and membrane integrity assays. However,…”
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