Search Results - "Wang, Chiayeng"
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Structural and functional studies of FKHR-PAX3, a reciprocal fusion gene of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma
Published in PloS one (14-06-2013)“…Alveolar rhabdomyosarcoma (ARMS) is an aggressive pediatric cancer of skeletal muscle. More than 70% of ARMS tumors carry balanced t(2;13) chromosomal…”
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2
Credentialing a Preclinical Mouse Model of Alveolar Rhabdomyosarcoma
Published in Cancer research (Chicago, Ill.) (01-04-2009)“…The highly aggressive muscle cancer alveolar rhabdomyosarcoma (ARMS) is one of the most common soft tissue sarcoma of childhood, yet the outcome for the…”
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3
Leydig Cell Loss and Spermatogenic Arrest in Platelet-Derived Growth Factor (PDGF)-A-Deficient Mice
Published in The Journal of cell biology (29-05-2000)“…Platelet-derived growth factor (PDGF)-A-deficient male mice were found to develop progressive reduction of testicular size, Leydig cells loss, and…”
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4
The COOH-terminal Transactivation Domain Plays a Key Role in Regulating the in Vitro and in Vivo Function of Pax3 Homeodomain
Published in The Journal of biological chemistry (31-03-2000)“…Efficient transcription activation by Pax3 requires binding to a complex DNA sequence element containing binding sites for both the paired domain and the Prd…”
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PAX3-FKHR Transformation Increases 26 S Proteasome-dependent Degradation of p27Kip1, a Potential Role for Elevated Skp2 Expression
Published in The Journal of biological chemistry (03-01-2003)“…PAX3-FKHR is an oncogenic form of the developmental regulator Pax3 transcription factor. PAX3-FKHR results from a t(2,13) chromosomal translocation, a unique…”
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6
Tumor-Specific PAX3-FKHR Transcription Factor, but Not PAX3, Activates the Platelet-Derived Growth Factor Alpha Receptor
Published in Molecular and Cellular Biology (01-07-1998)“…AUTHOR'S CORRECTION ( vol. 19 , p. 7287 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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7
PDGF and its receptors in the developing rodent retina and optic nerve
Published in Development (Cambridge) (01-06-1993)“…We have used in situ hybridization to visualize cells in the developing rat retina and optic nerve that express mRNAs encoding the A and B chains of…”
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Selective expression of PDGF A and its receptor during early mouse embryogenesis
Published in Developmental biology (01-03-1990)“…Murine homologs of the PDGF A, PDGF B, and PDGF receptor α subunit genes were cloned. These were used, together with a mouse PDGF receptor β subunit cDNA…”
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9
Unraveling Links between Chronic Inflammation and Long COVID: Workshop Report
Published in The Journal of immunology (1950) (15-02-2024)“…As COVID-19 continues, an increasing number of patients develop long COVID symptoms varying in severity that last for weeks, months, or longer. Symptoms…”
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10
Metabolic Regulation of Inflammation and Its Resolution: Current Status, Clinical Needs, Challenges, and Opportunities
Published in The Journal of immunology (1950) (01-12-2021)“…Metabolism and inflammation have been viewed as two separate processes with distinct but critical functions for our survival: metabolism regulates the…”
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Imaging inflammation and its resolution in health and disease: current status, clinical needs, challenges, and opportunities
Published in The FASEB journal (01-12-2019)“…Inflammation is a normal process in our body; acute inflammation acts to suppress infections and support wound healing. Chronic inflammation likely leads to a…”
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12
The Making of a PreCancer Atlas: Promises, Challenges, and Opportunities
Published in Trends in cancer (01-08-2018)“…Many cancers evolve from benign precancerous lesions and have a natural history of progression that provides a window of opportunity for intervention. The…”
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13
Post-transcriptional regulation of PDGFα-receptor in O-2A progenitor cells
Published in International journal of clinical and experimental medicine (01-01-2011)“…latelet-derived growth factor alpha-receptor (PDGFαR) mediated signaling plays a key role in the development of glial cells of the central nervous system. In…”
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14
Retinoic acid promotes transcription of the platelet-derived growth factor alpha-receptor gene
Published in Molecular and Cellular Biology (01-12-1990)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural and Functional Studies of FKHR-PAX3, a Reciprocal Fusion Gene of the t(2; 13) Chromosomal Translocation in Alveolar Rhabdomyosarcoma. e68065
Published in PloS one (01-06-2013)“…Alveolar rhabdomyosarcoma (ARMS) is an aggressive pediatric cancer of skeletal muscle. More than 70% of ARMS tumors carry balanced t(2; 13) chromosomal…”
Get full text
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16
Comparative analysis of paired- and homeodomain-specific roles in PAX3-FKHR oncogenesis
Published in International journal of clinical and experimental pathology (01-01-2009)“…The alveolar rhabdomyosarcoma-associated t(2;13) chromosomal translocation produces an oncogenic fusion transcription factor PAX3-FKHR that combines the…”
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17
Characterization of fodrin phosphorylation by spleen protein tyrosine kinase
Published in Biochemistry (Easton) (01-02-1988)“…Fodrin, an actin and calmodulin binding and spectrin-like protein present in many nonerythrocyte tissues, could be phosphorylated up to more than 1.5 mol of…”
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Genomic organization and expression of the rat TRPM-2 (clusterin) gene, a gene implicated in apoptosis
Published in The Journal of biological chemistry (05-03-1993)“…We describe the genomic structure of the rat TRPM-2 gene. This gene is induced de novo during the regression of the prostate and other hormone-dependent…”
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Platelet-derived growth factor (alpha) receptor gene expression: Isolation and characterization of the promoter and upstream regulatory elements
Published in Proceedings of the National Academy of Sciences - PNAS (19-07-1994)“…Genomic clones encompassing the 5' end of the mouse platelet-derived growth factor (PDGF) alpha receptor mRNA transcript were isolated, and ten kb was extended…”
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Platelet-Derived Growth Factor Receptor α-Subunit Gene (Pdgfra) is Deleted in the Mouse Patch (Ph) Mutation
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1991)“…Platelet-derived growth factor receptors are composed of two subunits (α and β) that associate with one another to form three functionally active dimeric…”
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