Search Results - "Wang, Charlotte I."
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genomic binding sites of a noncoding RNA
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-2011)“…Long noncoding RNAs (lncRNAs) have important regulatory roles and can function at the level of chromatin. To determine where lncRNAs bind to chromatin, we…”
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Chromatin proteins captured by ChIP–mass spectrometry are linked to dosage compensation in Drosophila
Published in Nature structural & molecular biology (01-02-2013)“…The MSL complex acts on chromatin to and is required for X-chromosome dosage compensation. Chromatin-interacting protein MS (ChIP-MS) is now used to identify…”
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A Sequence Motif within Chromatin Entry Sites Directs MSL Establishment on the Drosophila X Chromosome
Published in Cell (22-08-2008)“…The Drosophila MSL complex associates with active genes specifically on the male X chromosome to acetylate histone H4 at lysine 16 and increase expression…”
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upSET , the Drosophila homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks
Published in G3 : genes - genomes - genetics (01-02-2017)“…Chromatin plays a critical role in faithful implementation of gene expression programs. Different post-translational modifications (PTMs) of histone proteins…”
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T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes
Published in Cell (08-08-2019)“…T cell recognition of specific antigens mediates protection from pathogens and controls neoplasias, but can also cause autoimmunity. Our knowledge of T cell…”
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High-throughput discovery of MHC class I- and II-restricted T cell epitopes using synthetic cellular circuits
Published in Nature biotechnology (02-07-2024)“…Antigen discovery technologies have largely focused on major histocompatibility complex (MHC) class I-restricted human T cell receptors (TCRs), leaving methods…”
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Molecular testing of different cytologic preparations in patients with advanced lung adenocarcinoma: which yields the best results?
Published in Journal of the American Society of Cytopathology JASC (01-01-2017)“…Introduction This study constitutes the first systematic comparison of molecular results between different cytology preparations in patients with lung…”
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Identification of human α-synuclein specific single chain antibodies
Published in Biochemical and biophysical research communications (03-11-2006)“…Parkinson’s disease (PD) is a common neurodegenerative disease of unknown etiology. Evidence suggests a role for protein misfolding in disease pathogenesis…”
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A ChIP-mass spectrometry approach to analysis of dosage compensation in Drosophila
Published 01-01-2012“…Dosage compensation is a process that many multicellular organisms employ to equalize the expression of X-linked genes between males and females. In Drosophila…”
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Dissertation