Search Results - "Wang, Changnan"

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  1. 1

    Attenuation of Sepsis-Induced Acute Kidney Injury by Exogenous H2S via Inhibition of Ferroptosis by Zhang, Li, Rao, Jin, Liu, Xuwen, Wang, Xuefu, Wang, Changnan, Fu, Shangxi, Xiao, Jian

    Published in Molecules (Basel, Switzerland) (14-06-2023)
    “…Sepsis-associated acute kidney injury (SA-AKI) results in significant morbidity and mortality, and ferroptosis may play a role in its pathogenesis. Our aim was…”
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    Journal Article
  2. 2

    Reduced hydrogen sulfide production contributes to adrenal insufficiency induced by hypoxia via modulation of NLRP3 inflammasome activation by Zhang, Ningning, Zhou, Zhan, Huang, Yan, Wang, Gang, Tang, Zhengshan, Lu, Jianqiang, Wang, Changnan, Ni, Xin

    “…Objective: Adrenocortical responsiveness is critical for maintaining glucocorticoids production and homeostasis during stress. We sought to investigate…”
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  3. 3

    Skeletal muscle cystathionine γ-lyase deficiency promotes obesity and insulin resistance and results in hyperglycemia and skeletal muscle injury upon HFD in mice by Lu, Jiani, Tang, Zhengshan, Xu, Miaomiao, Lu, Jianqiang, Wang, Fengmei, Ni, Xin, Wang, Changnan, Yu, Bo

    “…The objective of this study was to investigate whether skeletal muscle cystathionine γ-lyase (CTH) contributes to high-fat diet (HFD)-induced metabolic…”
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    Journal Article
  4. 4

    LPD-3 as a megaprotein brake for aging and insulin-mTOR signaling in C. elegans by Pandey, Taruna, Wang, Bingying, Wang, Changnan, Zu, Jenny, Deng, Huichao, Shen, Kang, do Vale, Goncalo Dias, McDonald, Jeffrey G., Ma, Dengke K.

    Published in Cell reports (Cambridge) (26-03-2024)
    “…Insulin-mechanistic target of rapamycin (mTOR) signaling drives anabolic growth during organismal development; its late-life dysregulation contributes to aging…”
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  5. 5

    A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience by Wang, Changnan, Wang, Bingying, Pandey, Taruna, Long, Yong, Zhang, Jianxiu, Oh, Fiona, Sima, Jessica, Guo, Ruyin, Liu, Yun, Zhang, Chao, Mukherjee, Shaeri, Bassik, Michael, Lin, Weichun, Deng, Huichao, Vale, Goncalo, McDonald, Jeffrey G., Shen, Kang, Ma, Dengke K.

    Published in Nature communications (10-11-2022)
    “…Cells adapt to cold by increasing levels of unsaturated phospholipids and membrane fluidity through conserved homeostatic mechanisms. Here we report an…”
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  6. 6

    Late Jurassic Wenjiaping high Sr/Y granite: A product of partial melting of the Precambrian basement rocks trigged by lithospheric extension in the Songpan–Garzê fold belt, SW China by Liu, Jun, Li, Wenchang, Zhou, Qing, Zhang, Huihua, Li, Tongzhu, Dai, Yanpei, Shen, Zhanwu, Tang, Gaolin, Wang, Changnan

    Published in Geological journal (Chichester, England) (01-10-2022)
    “…The Wenjiaping granite, as one of the few Late Jurassic granites in the Songpan–Garzê fold belt (SGFB), can provide an important clue for comprehensively…”
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  7. 7

    The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex by Wang, Xin, Jiang, Wei, Luo, Shuo, Yang, Xiaoyu, Wang, Changnan, Wang, Bingying, Dang, Yongjun, Shen, Yin, Ma, Dengke K

    Published in Molecular brain (16-03-2021)
    “…TMEM132D is a human gene identified with multiple risk alleles for panic disorders, anxiety and major depressive disorders. Defining a conserved family of…”
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  8. 8

    Pennsylvanian–early Permian palaeokarst development on the Yangtze Platform, South China, and implications for the regional sea‐level history by Huang, Xing, Aretz, Markus, Zhang, Xionghua, Du, Yuansheng, Qie, Wenkun, Wen, Qin, Wang, Changnan, Luan, Tengfei, Wang, X.‐d.

    Published in Geological journal (Chichester, England) (01-07-2018)
    “…The Pennsylvanian to lower Permian succession at Madiyi, South China, represents a nearshore mixed siliciclastic‐carbonate system characterized by cyclic…”
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    Journal Article
  9. 9

    Endotoxin tolerance of adrenal gland: Attenuation of corticosterone production in response to lipopolysaccharide and adrenocorticotropic hormone by Liu, Shujuan, Zhu, Xiaoyan, Liu, Yujian, Wang, Changnan, Wang, Shan, Tang, Xiaolu, Ni, Xin

    Published in Critical care medicine (01-03-2011)
    “…OBJECTIVES:Reversible adrenal insufficiency frequently has been diagnosed in critically ill patients with sepsis who have either low basal cortisol levels or…”
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  10. 10

    Resveratrol alleviates acute lung injury through regulating PLSCR-3-mediated mitochondrial dysfunction and mitophagy in a cecal ligation and puncture model by Wang, Changnan, Yuan, Jihong, Du, Jiankui

    Published in European journal of pharmacology (15-12-2021)
    “…Sepsis is considered as a life-threatening organ dysfunction caused by a dysregulated response of the host to an infection. Acute lung injury (ALI)/acute…”
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    Journal Article
  11. 11

    Attenuation of Sepsis-Induced Acute Kidney Injury by Exogenous H[sub.2]S via Inhibition of Ferroptosis by Zhang, Li, Rao, Jin, Liu, Xuwen, Wang, Xuefu, Wang, Changnan, Fu, Shangxi, Xiao, Jian

    Published in Molecules (Basel, Switzerland) (01-06-2023)
    “…Sepsis-associated acute kidney injury (SA-AKI) results in significant morbidity and mortality, and ferroptosis may play a role in its pathogenesis. Our aim was…”
    Get full text
    Journal Article
  12. 12

    GPCR signaling regulates severe stress‐induced organismic death in Caenorhabditis elegans by Wang, Changnan, Long, Yong, Wang, Bingying, Zhang, Chao, Ma, Dengke K.

    Published in Aging cell (01-01-2023)
    “…How an organism dies is a fundamental yet poorly understood question in biology. An organism can die of many causes, including stress‐induced phenoptosis, also…”
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  13. 13

    Endogenous H2S resists mitochondria-mediated apoptosis in the adrenal glands via ATP5A1 S-sulfhydration in male mice by Wang, Changnan, Du, Jiankui, Du, Shufang, Liu, Yujian, Li, Dongxia, Zhu, Xiaoyan, Ni, Xin

    Published in Molecular and cellular endocrinology (15-10-2018)
    “…In a previous study, we showed that endogenous hydrogen sulfide (H2S) plays a key role in the maintenance of intact adrenal cortex function via the protection…”
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    Journal Article
  14. 14

    " Yin-Yang philosophy" for the design of anticancer drug delivery nanoparticles by Ai, Yanwen, Tian, Yuan, Qiao, Jiaming, Wang, Changnan, Li, Huafei

    Published in Biomaterials translational (2024)
    “…Understanding the in vivo transport process provides guidelines for designing ideal nanoparticles (NPs) with higher efficacy and fewer off-target effects. Many…”
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  15. 15

    Hydrogen Sulfide Is a Regulator of Hemoglobin Oxygen-Carrying Capacity via Controlling 2,3-BPG Production in Erythrocytes by Wang, Gang, Huang, Yan, Zhang, Ningning, Liu, Wenhu, Wang, Changnan, Zhu, Xiaoyan, Ni, Xin

    “…Hydrogen sulfide (H2S) is naturally synthesized in a wide range of mammalian tissues. Whether H2S is involved in the regulation of erythrocyte functions…”
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  16. 16

    Estrogens increase cystathionine-γ-lyase expression and decrease inflammation and oxidative stress in the myocardium of ovariectomized rats by Zhu, Xiaoyan, Tang, Zhiping, Cong, Binhai, Du, Jiankui, Wang, Changnan, Wang, Long, Ni, Xin, Lu, Jianqiang

    Published in Menopause (New York, N.Y.) (01-10-2013)
    “…OBJECTIVEHydrogen sulfide (H2S), generated in the myocardium predominantly via cystathionine-γ-lyase (CSE), is cardioprotective. The objectives of the present…”
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    Journal Article
  17. 17

    Endogenous H 2 S resists mitochondria-mediated apoptosis in the adrenal glands via ATP5A1 S-sulfhydration in male mice by Wang, Changnan, Du, Jiankui, Du, Shufang, Liu, Yujian, Li, Dongxia, Zhu, Xiaoyan, Ni, Xin

    Published in Molecular and cellular endocrinology (15-10-2018)
    “…In a previous study, we showed that endogenous hydrogen sulfide (H S) plays a key role in the maintenance of intact adrenal cortex function via the protection…”
    Get full text
    Journal Article
  18. 18

    Attenuation of Sepsis-Induced Acute Kidney Injury by Exogenous H 2 S via Inhibition of Ferroptosis by Zhang, Li, Rao, Jin, Liu, Xuwen, Wang, Xuefu, Wang, Changnan, Fu, Shangxi, Xiao, Jian

    Published in Molecules (Basel, Switzerland) (14-06-2023)
    “…Sepsis-associated acute kidney injury (SA-AKI) results in significant morbidity and mortality, and ferroptosis may play a role in its pathogenesis. Our aim was…”
    Get full text
    Journal Article