Search Results - "Wang, Beiyun"

Inhibition of NF-kappaB activation by Pyrrolidine dithiocarbamate partially attenuates hippocampal MMP-9 activation and improves cognitive deficits in streptozotocin-induced diabetic rats by Zhao, Zhe, Huang, Gaozhong, Wang, Beiyun, Zhong, Yuan

“…► Hippocampal MMP-9 up-regulation paralleled with diabetes-induced cognitive decline. ► PDTC treatment in diabetic rats returned NF-κB levels toward their…”
Get full text

Inflammatory Macrophages Promotes Development of Diabetic Encephalopathy by Wang, Beiyun, Miao, Ya, Zhao, Zhe, Zhong, Yuan

“…Background/Aims: Diabetes and Alzheimer's disease are often associated with each other, whereas the relationship between two diseases is ill-defined. Although…”
Get full text

Alterations in metamemory capacity and neural correlates in a subtype of subjective cognitive decline by Li, Qinjie, Sun, Xiaokang, Cui, Liang, Zhong, Yuan, Wang, Beiyun, Miao, Ya, Hu, Xiaochen, Guo, Qihao

“…•There is a discrepancy between self-report and objective memory performance in SCD.•A subtype of SCD tended to be overconfident on memory…”
Get full text

Stereoselective metabolism of donepezil and steady-state plasma concentrations of S-donepezil based on CYP2D6 polymorphisms in the therapeutic responses of Han Chinese patients with Alzheimer's disease by Lu, Jin, Wan, Lili, Zhong, Yuan, Yu, Qi, Han, Yonglong, Chen, Pengguo, Wang, Beiyun, Li, Wei, Miao, Ya, Guo, Cheng

“…The therapeutic response rates of patients to donepezil vary from 20% to 60%, one of the reasons is their genetic differences in donepezil-metabolizing…”
Get full text

Effect of CYP2D610 and APOE Polymorphisms on the Efficacy of Donepezil in Patients With Alzheimer’s Disease by Zhong, Yuan, MD, Zheng, Xueli, MD, Miao, Ya, MD, PhD, Yan, Hong, BD, Wang, Beiyun, MD, Wan, Lili, MD

“…Abstract Background The aim of this study was to evaluate the effect of CYP2D6*10 and APOE polymorphisms on both steady-state plasma concentrations (Cp) and…”
Get full text

Myricetin ameliorates scopolamine-induced memory impairment in mice via inhibiting acetylcholinesterase and down-regulating brain iron by Wang, Beiyun, Zhong, Yuan, Gao, Chengjie, Li, Jingbo

“…The aim of our study was to investigate to investigate the effect of myricetin on Alzheimer's disease (AD) and its underlying mechanisms. In our study,…”
Get full text

Autophagy of macrophages is regulated by PI3k/Akt/mTOR signalling in the development of diabetic encephalopathy by Wang, Beiyun, Zhong, Yuan, Li, Qinjie, Cui, Liang, Huang, Gaozhong

“…The development of diabetic encephalopathy (DE) is enhanced by inflammatory macrophages, and is suppressed by macrophage autophagy. However, the molecular…”
Get full text

Plasma Aβ as a biomarker for predicting Aβ-PET status in Alzheimer’s disease：a systematic review with meta-analysis by Cheng, Lizhen, Li, Wei, Chen, Yixin, Lin, Yijia, Wang, Beiyun, Guo, Qihao, Miao, Ya

“…ObjectiveAmyloid-β positron emission tomography (Aβ-PET) scan has been proposed to detect amyloid-β (Aβ) deposition in the brain. However, this approach is…”
Get full text

Circular RNA DLGAP4 is down-regulated and negatively correlates with severity, inflammatory cytokine expression and pro-inflammatory gene miR-143 expression in acute ischemic stroke patients by Zhu, Xiaoqi, Ding, Ji, Wang, Beiyun, Wang, Jie, Xu, Min

“…This study aimed to investigate the expression of circular RNA DLGAP4 (circ-DLGAP4) and its correlation with severity, inflammation, inflammatory cytokine…”
Get full text

Control of macrophage autophagy by miR-384-5p in the development of diabetic encephalopathy by Wang, Beiyun, Huang, Jing, Li, Jingbo, Zhong, Yuan

“…The molecular development of diabetic encephalopathy remains ill-defined. Recently, we reported that elimination of inflammatory macrophages alleviated the…”
Get full text

Macrophage autophagy regulated by miR-384-5p-mediated control of Beclin-1 plays a role in the development of atherosclerosis by Wang, Beiyun, Zhong, Yuan, Huang, Dong, Li, Jingbo

“…Macrophages play an essential and complicated role in the pathogenesis of atherosclerosis. However, the regulation of macrophage autophagy as well as it role…”
Get full text

Meta-analysis of plasma homocysteine content and cognitive function in elderly patients with Alzheimer's disease and vascular dementia by Wang, Beiyun, Zhong, Yuan, Yan, Hong, Cui, Liang

“…To evaluate the relationship between homocysteine and cognitive function of Alzheimer's disease (AD) patients and vascular dementia (VD) patients. By Cochrane…”
Get full text

Mecobalamin and early functional outcomes of ischemic stroke patients with H-type hypertension by Yuan, Meixia, Wang, Beiyun, Tan, Shijin

“…SUMMARY OBJECTIVE To analyze the effect of mecobalamin on the early-functional outcomes of patients with ischemic stroke and H-type hypertension. METHODS From…”
Get full text