Search Results - "Wang, Alun"

20(S)-protopanaxadiol inhibition of progression and growth of castration-resistant prostate cancer by Cao, Bo, Qi, Yanfeng, Yang, Yan, Liu, Xichun, Xu, Duo, Guo, Wei, Zhan, Yang, Xiong, Zhenggang, Zhang, Allen, Wang, Alun R, Fu, Xueqi, Zhang, Haitao, Zhao, Lijing, Gu, Jingkai, Dong, Yan

“…Castration-resistant progression of prostate cancer after androgen deprivation therapies remains the most critical challenge in the clinical management of…”
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Richard J. Reed, MD (1928–2021) by Daroca, Philip J., Wang, Alun R.

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Pembrolizumab‐induced pseudoepitheliomatous eruption consistent with hypertrophic lichen planus by Coscarart, Aimee, Martel, Julianna, Lee, Michael P., Wang, Alun R.

“…Pembrolizumab, an anti‐programmed cell death‐1 (PD‐1) antibody preparation, has been shown to induce various dermatologic adverse events which may present with…”
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Case report: Rubella virus-induced cutaneous granulomas in a girl with atypical SCID caused by DCLRE1C gene mutations by Deng, Sihan, Rao, Shijia, Wang, Alun R, Shi, Wei

“…Here, we report a case of rubella virus-induced granulomatous dermatitis in a young girl with immunodeficiency caused by gene mutations. The patient was a…”
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BATF-dependent Th17 cells act through the IL-23R pathway to promote prostate adenocarcinoma initiation and progression by Liu, Sen, Rivero, Seleste L, Zhang, Bing, Shen, Keyi, Li, Zixuan, Niu, Tianhua, Rowan, Brian G, Jazwinski, S Michal, Abdel-Mageed, Asim B, Steele, Chad, Wang, Alun R, Sartor, Oliver, Zhang, Qiuyang

“…The role of Th17 cells in prostate cancer is not fully understood. The transcription factor BATF controls the differentiation of Th17 cells. Mice deficient in…”
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Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment by Zhang, Qiuyang, Liu, Sen, Zhang, Qingsong, Xiong, Zhenggang, Wang, Alun R., Myers, Leann, Melamed, Jonathan, Tang, Wendell W., You, Zongbing

“…BACKGROUND Interleukin‐17 (IL‐17) has been demonstrated to promote formation and growth of hormone‐naïve prostate adenocarcinoma in mice. IL‐17's role in…”
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Calcium signaling and T-type calcium channels in cancer cell cycling by Taylor, James T, Zeng, Xiang-Bin, Pottle, Jonathan E, Lee, Kevin, Wang, Alun R, Yi, Stephenie G, Scruggs, Jennifer A S, Sikka, Suresh S, Li, Ming

“…Regulation of intracellular calcium is an important signaling mechanism for cell proliferation in both normal and cancerous cells. In normal epithelial cells,…”
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SCF[sup.FBXW11] Complex Targets Interleukin-17 Receptor A for Ubiquitin–Proteasome-Mediated Degradation by Jin, Ben, Moududee, Sayed Ala, Ge, Dongxia, Zhou, Pengbo, Wang, Alun R, Liu, Yao-Zhong, You, Zongbing

“…Interleukin-17 (IL-17) is a pro-inflammatory cytokine that participates in innate and adaptive immune responses and plays an important role in host defense,…”
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Prognostic Role of BRAFV600E Cellular Localization in Melanoma by Abd Elmageed, Zakaria Y., Moore, Robert F., Tsumagari, Koji, Lee, Michael M., Sholl, Andrew B., Friedlander, Paul, Al-Qurayshi, Zaid, Hassan, Mohamed, Wang, Alun R., Boulares, Hamid A., Kandil, Emad

“…Approximately half of cutaneous melanoma tissues harbor BRAFV600E mutations, resulting in a constitutive activation of the mitogen-activated protein kinase…”
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Defect of IL17 Signaling, but Not Centrinone, Inhibits the Development of Psoriasis and Skin Papilloma in Mouse Models by Jin, Ben, Zhang, Yongfeng, Miller, Haiyan D, He, Ling, Ge, Dongxia, Wang, Alun R, You, Zongbing

“…Patients with psoriasis tend to develop skin cancer, and the hyperproliferation of the epidermis is a histopathological hallmark of both psoriasis and…”
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SCFFBXW11 Complex Targets Interleukin-17 Receptor A for Ubiquitin–Proteasome-Mediated Degradation by Jin, Ben, Moududee, Sayed Ala, Ge, Dongxia, Zhou, Pengbo, Wang, Alun R., Liu, Yao-Zhong, You, Zongbing

“…Interleukin-17 (IL-17) is a pro-inflammatory cytokine that participates in innate and adaptive immune responses and plays an important role in host defense,…”
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Overactivation of histone deacetylases and EZH2 in Wilms tumorigenesis by Chen, Chao-Hui, Ngo, Nguyen Yen Nhi, Wang, Alun, El-Dahr, Samir, Liu, Hongbing

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Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor by Liu, Sen, Zhang, Qiuyang, Chen, Chong, Ge, Dongxia, Qu, Yine, Chen, Rongyi, Fan, Yi-Ming, Li, Nan, Tang, Wendell W, Zhang, Wensheng, Zhang, Kun, Wang, Alun R, Rowan, Brian G, Hill, Steven M, Sartor, Oliver, Abdel-Mageed, Asim B, Myers, Leann, Lin, Qishan, You, Zongbing

“…Interleukin-17 (IL-17) plays important roles in inflammation, autoimmune diseases, and some cancers. Obese people are in a chronic inflammatory state with…”
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PD-1, PD-L1 and PD-L2 expression in mouse prostate cancer by Yang, Shijie, Zhang, Qiuyang, Liu, Sen, Wang, Alun R, You, Zongbing

“…Programmed cell death protein 1 (PD-1) and its ligands PD-L1 and PD-L2 play critical roles in maintaining an immunosuppressive tumor microenvironment. The…”
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A Novel Controlled PTEN-Knockout Mouse Model for Prostate Cancer Study by Liu, Sen, Zhang, Bing, Rowan, Brian G, Jazwinski, S Michal, Abdel-Mageed, Asim B, Steele, Chad, Wang, Alun R, Sartor, Oliver, Niu, Tianhua, Zhang, Qiuyang

“…Prostate cancer (PCa) is associated with advanced age, but how age contributes to prostate carcinogenesis remains unknown. The prostate-specific Pten…”
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Mammary Paget Disease With Melanocytic Proliferation Mimicking Malignant Melanoma in situ : A Case Report by Rao, Shijia, Wang, Alun, Liu, Wei, Yin, Hongling, Li, Ji, Tsang, Lemuel Shui-Lun, Wu, Yuhui, Shi, Wei

“…Several cases of pigmented mammary Paget's disease (PMPD) mimicking cutaneous malignant melanoma have been reported. In these cases, the tumor cells are…”
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Composite lymphoid neoplasm of B-cell and T-cell origins: a pathologic study of 14 cases by Wang, Endi, MD, PhD, Papavassiliou, Paulie, MD, PhD, Wang, Alun R., MD, PhD, Louissaint, Abner, MD, PhD, Wang, Jun, MD, Hutchinson, Charles Blake, MD, Huang, Qin, MD, PhD, Reddi, Deepti, MD, Wei, Qiang, MD, PhD, Sebastian, Siby, PhD, Rehder, Catherine, PhD, Brynes, Russell, MD, Siddiqi, Imran, MD, PhD

“…Summary We retrospectively analyzed 14 composite lymphoma/lymphoid neoplasms (CL) of B-cell/T-cell origins. These consisted of a spectrum of T-cell neoplasms…”
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Orf virus infection after Eid al-Adha by Vellucci, Ashley, Manolas, Melina, Jin, Sarah, Dwyer, John, Vick, Garrett, Wang, Alun, Swiatlo, Edwin, Zheng, Crystal

“…Human orf, also called ecthyma contagiosum, is a zoonotic infection that causes self-resolving skin lesions after contact with infected livestock. We present…”
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Composite lymphoma of mycosis fungoides and cutaneous small B-cell lymphoma in a 73-year-old male patient by Whitling, Nicholas A., MD, Shanesmith, Rebecca P., MD, Jacob, Leah, MD, McBurney, Elizabeth, MD, Sebastian, Siby, PhD, Wang, Endi, MD, PhD, Wang, Alun R., MD, PhD

“…Summary Composite lymphoma of T-cell and B-cell type is uncommon, and the one occurring primarily on skin is extremely rare. Herein, we report a unique case of…”
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Human adipose-derived stromal/stem cells expressing doublecortin improve cartilage repair in rabbits and monkeys by Ge, Dongxia, O’Brien, Michael J., Savoie, Felix H., Gimble, Jeffrey M., Wu, Xiying, Gilbert, Margaret H., Clark-Patterson, Gabrielle L., Schuster, Jason D., Miller, Kristin S., Wang, Alun, Myers, Leann, You, Zongbing

“…Localized cartilage lesions in early osteoarthritis and acute joint injuries are usually treated surgically to restore function and relieve pain. However, a…”
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