Search Results - "Wanek, Leslie A"

Improved Survival for Stage IV Melanoma From an Unknown Primary Site by LEE, Chris C, FARIES, Mark B, WANEK, Leslie A, MORTON, Donald L

“…PURPOSE We previously demonstrated a survival advantage for nodal metastasis of melanoma from an unknown primary (MUP) versus melanoma from a known primary…”
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Improved Survival After Lymphadenectomy for Nodal Metastasis From an Unknown Primary Melanoma by LEE, Chris C, FARIES, Mark B, WANEK, Leslie A, MORTON, Donald L

“…No primary lesion is identified in 10% to 20% of patients presenting with palpable evidence of regional metastatic melanoma. Because the prognostic…”
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Role of Sentinel Lymphadenectomy in Thin Invasive Cutaneous Melanomas by BLEICHER, Richard J, ESSNER, Richard, FOSHAG, Leland J, WANEK, Leslie A, MORTON, Donald L

“…Regional lymph node status is the strongest prognostic determinant in early-stage melanoma. Lymphatic mapping and sentinel lymphadenectomy (LM/SL) is standard…”
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Sentinel Lymphadenectomy Does Not Increase the Incidence of In-Transit Metastases in Primary Melanoma by KANG, John C, WANEK, Leslie A, ESSNER, Richard, FANES, Mark B, FOSHAG, Leland J, MORTON, Donald L

“…Recent reports by European investigators suggest that sentinel lymphadenectomy (SLND), a mainstay of melanoma diagnosis and treatment planning, increases the…”
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Enhanced Humoral Immune Response Correlates With Improved Disease-Free and Overall Survival in American Joint Committee on Cancer Stage II Melanoma Patients Receiving Adjuvant Polyvalent Vaccine by DIFRONZO, L. Andrew, GUPTA, Rishab K, ESSNER, Richard, FOSHAG, Leland J, O'DAY, Steven J, WANEK, Leslie A, STERN, Stacey L, MORTON, Donald L

“…Although the improved overall survival (OS) of patients who receive Canvaxin (CancerVax Corp, Carlsbad, CA) polyvalent vaccine (PV) immunotherapy for…”
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Resection and adjuvant immunotherapy for melanoma metastatic to the lung and thorax by Tafra, Lorraine, Dale, Paul S., Wanek, Leslie A., Ramming, Kenneth P., Morton, Donald L.

“…Although melamoma that metastasizes to distant sites is generally associated with a median survival of only 6 to 8 months, certain metastatic sites including…”
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Lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: therapeutic utility and implications of nodal microanatomy and molecular staging for improving the accuracy of detection of nodal micrometastases by Morton, Donald L, Hoon, Dave S B, Cochran, Alistair J, Turner, Roderick R, Essner, Richard, Takeuchi, Hiroya, Wanek, Leslie A, Glass, Edwin, Foshag, Leland J, Hsueh, Eddy C, Bilchik, Anton J, Elashoff, David, Elashoff, Robert

“…Lymphatic mapping and sentinel lymphadenectomy (LM/SL) have been applied to virtually all solid neoplasms since our original description of LM/SL for melanoma…”
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Prolonged survival of patients receiving active immunotherapy with Canvaxin therapeutic polyvalent vaccine after complete resection of melanoma metastatic to regional lymph nodes by Morton, Donald L, Hsueh, Eddy C, Essner, Richard, Foshag, Leland J, O'Day, Steven J, Bilchik, Anton, Gupta, Rishab K, Hoon, Dave S B, Ravindranath, Mepur, Nizze, J Anne, Gammon, Guy, Wanek, Leslie A, Wang, He-Jing, Elashoff, Robert M

“…To determine whether adjuvant postoperative active specific immunotherapy with a therapeutic polyvalent vaccine (PV) called Canvaxin can prolong survival…”
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Earlier diagnosis of second primary melanoma confirms the benefits of patient education and routine postoperative follow‐up by DiFronzo, L. Andrew, Wanek, Leslie A., Morton, Donald L.

“…BACKGROUND Rising health care costs have caused providers to question the benefit of regular follow‐up after treatment for patients with early stage cutaneous…”
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Is sentinel lymph node mapping indicated for isolated local and in-transit recurrent melanoma? by YAO, Katharine A, HSUEH, Eddy C, ESSNER, Richard, FOSHAG, Leland J, WANEK, Leslie A, MORTON, Donald L

“…To determine the feasibility of sentinel lymph node mapping in local and in-transit recurrent melanoma. The accuracy of intraoperative lymphatic mapping and…”
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Is adjuvant radiotherapy necessary after positive lymph node dissection in head and neck melanomas? by Shen, P, Wanek, L A, Morton, D L

“…Postoperative radiotherapy (PR) has been recommended in patients with advanced head and neck melanomas to improve regional control. This study examined the…”
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Increased incidence of second primary melanoma in patients with a previous cutaneous melanoma by DiFronzo, L A, Wanek, L A, Elashoff, R, Morton, D L

“…Patients with cutaneous melanoma reportedly have an increased risk of developing second primary melanoma; however, this increased risk has not been well…”
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Endogenous immune response to early- and intermediate-stage melanoma is correlated with outcomes and is independent of locoregional relapse and standard prognostic factors by Litvak, David A, Gupta, Rishab K, Yee, Reynold, Wanek, Leslie A, Ye, Wei, Morton, Donald L

“…Standard prognostic factors, including precise staging of the regional lymph nodes, cannot accurately determine which early-stage melanomas will metastasize…”
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Can surgical therapy alone achieve long-term cure of melanoma metastatic to regional nodes? by Young, Shawn E, Martinez, Steve R, Faries, Mark B, Essner, Richard, Wanek, Leslie A, Morton, Donald L

“…Anecdotal reports of melanoma recurrence 15 years after complete lymphadenectomy have led to claims that the onset of nodal metastasis invariably signals…”
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Judging the therapeutic value of lymph node dissections for melanoma by Chan, Arden D, Essner, Richard, Wanek, Leslie A, Morton, Donald L

“…Background: The management of the regional lymph nodes remains controversial for early-stage melanoma and for those patients with lymph node metastases;…”
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Predictors of occult nodal metastasis in patients with thin melanoma by Faries, Mark B, Wanek, Leslie A, Elashoff, David, Wright, Byron E, Morton, Donald L

“…Thin primary lesions are largely responsible for the rapid increase in melanoma incidence, making identification of appropriate candidates for nodal staging in…”
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Contemporary surgical treatment of advanced-stage melanoma by Essner, Richard, Lee, Jonathan H, Wanek, Leslie A, Itakura, Hitoe, Morton, Donald L

“…The clinical treatment of patients with stage IV melanoma according to criteria of the American Joint Committee on Cancer (AJCC) is controversial because the…”
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Can elective lymph node dissection decrease the frequency and mortality rate of late melanoma recurrences? by Shen, P, Guenther, J M, Wanek, L A, Morton, D L

“…Although more than 90% of the morbidity and mortality from localized cutaneous melanoma occurs in the first decade after initial surgical treatment, melanoma…”
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Surgical management of the groin lymph nodes in melanoma in the era of sentinel lymph node dissection by Essner, Richard, Scheri, Randall, Kavanagh, Maihgan, Torisu-Itakura, Hitoe, Wanek, Leslie A, Morton, Donald L

“…Intraoperative lymphatic mapping and sentinel lymphadenectomy (LM/SL) has become an increasingly popular surgical technique for staging the regional lymph…”
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Lymph node biopsy does not impair survival after therapeutic dissection for palpable melanoma metastases by Kelemen, P R, Wanek, L A, Morton, D L

“…To determine the effects of disrupting a nodal basin in patients with American Joint Committee on Cancer stage III melanoma with clinically palpable lymph…”
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