Search Results - "Wandzik, Ilona"
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A Mini-Review on Chitosan-Based Hydrogels with Potential for Sustainable Agricultural Applications
Published in Polymers (21-10-2020)“…Agriculture is an important sector of the economy, but this industry consumes significant amounts of water, which is a precious and limited natural resource…”
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pH and Reduction Dual-Responsive Nanogels as Smart Nanocarriers to Resist Doxorubicin Aggregation
Published in Molecules (Basel, Switzerland) (01-09-2022)“…The use of smart nanocarriers that can modulate therapeutic release aided by biological cues can prevent undesirable cytotoxicity caused by the premature…”
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3
A Simple Synthesis of Reduction-Responsive Acrylamide-Type Nanogels for miRNA Delivery
Published in Molecules (Basel, Switzerland) (12-01-2023)“…MicroRNAs (miRNAs) have great therapeutic potential; however, their delivery still faces huge challenges, especially given the short half-life of naked miRNAs…”
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Nanogels with covalently bound and releasable trehalose for autophagy stimulation in atherosclerosis
Published in Journal of nanobiotechnology (08-12-2023)“…Atherosclerosis, cholesterol-driven plaque formation in arteries, is a complex multicellular disease which is a leading cause of vascular diseases. During the…”
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Correction: Nanogels with covalently bound and releasable trehalose for autophagy stimulation in atherosclerosis
Published in Journal of nanobiotechnology (17-01-2024)Get full text
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Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus
Published in Molecules (Basel, Switzerland) (21-03-2019)“…Tick-borne encephalitis virus (TBEV) is a causative agent of tick-borne encephalitis (TBE), one of the most important human infections involving the central…”
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Anti-Hepatitis C Virus Activity of Uridine Derivatives of 2-Deoxy Sugars
Published in Molecules (Basel, Switzerland) (27-06-2018)“…Hepatitis C virus (HCV), the etiological agent of the most common and dangerous diseases of the liver, is a major health problem worldwide. Despite many…”
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Biological Evaluation of Uridine Derivatives of 2-Deoxy Sugars as Potential Antiviral Compounds against Influenza A Virus
Published in International journal of molecular sciences (04-08-2017)“…Influenza virus infection is a major cause of morbidity and mortality worldwide. Due to the limited ability of currently available treatments, there is an…”
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Perfluoroalkylation of Nitrones for the Synthesis of a Series of Fucosidase Inhibitors
Published in European journal of organic chemistry (01-02-2015)“…Fucosidase inhibitors represent captivating targets for various biological applications. Iminosugars featuring a fluoroalkyl chain in the pseudoanomeric…”
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In vitro antiviral activity of some uridine derivatives of 2-deoxy sugars against classical swine fever virus
Published in Antiviral research (01-05-2010)“…Classical swine fever virus glycoproteins: E2, E rns (E0) and E1 are detected on the external part of viral particles and play a major role in the initial…”
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Synthesis and preliminary biological evaluations of 5'-substituted derivatives of uridine as glycosyltransferase inhibitors
Published in Molecules (Basel, Switzerland) (08-07-2013)“…New derivatives of uridine which contain a b-ketoenol motif were synthesized, characterized and biologically tested. Synthesized compounds 1-4 showed no…”
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Simultaneous Removal of Benzyl and Benzyloxycarbonyl Protective Groups in 5′-O-(2-Deoxy-α-D-Glucopyranosyl)Uridine by Catalytic Transfer Hydrogenolysis
Published in Nucleosides, nucleotides & nucleic acids (01-12-2008)“…Synthesis of N 3 ,2′,3′-O-tris-(benzyloxycarbonyl)uridine and its use in the synthesis of 5′-O-(2-deoxy-α-d-glucopyranosyl)uridine is described. Simultaneous…”
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Synthetic Hydrogels with Covalently Incorporated Saccharides Studied for Biomedical Applications - 15 Year Overview
Published in Polymer reviews (03-07-2018)“…Glycosylated materials have attracted special attention in biomedical field because of the unique properties of the individual carbohydrates in recognition…”
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Trehalose-Bearing Carriers to Target Impaired Autophagy and Protein Aggregation Diseases
Published in Journal of medicinal chemistry (14-12-2023)“…In recent years, trehalose, a natural disaccharide, has attracted growing attention because of the discovery of its potential to induce autophagy. Trehalose…”
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Selected nucleos(t)ide-based prescribed drugs and their multi-target activity
Published in European journal of pharmacology (15-12-2019)“…Nucleos(t)ide analogues play pivotal roles as antiviral, cytotoxic or immunosuppressive agents. Here, we review recent reports of nucleoside analogues that…”
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Trehalose-Rich, Degradable Hydrogels Designed for Trehalose Release under Physiologically Relevant Conditions
Published in Polymers (06-12-2019)“…Trehalose, a natural disaccharide, is primarily known for its ability to protect proteins from inactivation and denaturation caused by a variety of stress…”
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Functional (mikto)stars and star-comb copolymers from d-gluconolactone derivative: An efficient route for tuning the architecture and responsiveness to stimuli
Published in Polymer (Guilford) (20-06-2018)“…Stimuli responsive star-shaped poly (N,N′-dimethylaminoethyl methacrylate-co-2-hydroxyethyl methacrylate)s P (DMAEMA-co-HEMA) bearing gluconamide-based unit…”
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Study on protein release from hydrolytically degradable hydrogels governed by substituent effects in trehalose-based crosslinker and network properties
Published in European polymer journal (01-02-2019)“…[Display omitted] •Novel acid-labile trehalose-based benzylidene diacetal crosslinkers were synthesized.•Various substitutions on aromatic ring allows for…”
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The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes
Published in The Journal of biological chemistry (01-02-2023)“…Tetraspanins are transmembrane signaling and proinflammatory proteins. Prior work demonstrates that the tetraspanin, CD53/TSPAN25/MOX44, mediates B-cell…”
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Thermoresponsive hydrogels with covalently incorporated trehalose as protein carriers
Published in Reactive & functional polymers (01-10-2017)“…A series of thermoresponsive hydrogels containing covalently incorporated trehalose, the well-known protein stabilizing disaccharide, was synthesized with the…”
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