Search Results - "Wands, Jack"

Prevalence and Characteristics of Nonalcoholic Fatty Liver Disease and Fibrosis in People Living With HIV Monoinfection: A Systematic Review and Meta-analysis by Kalligeros, Markos, Vassilopoulos, Athanasios, Shehadeh, Fadi, Vassilopoulos, Stephanos, Lazaridou, Ingrid, Mylonakis, Eleftherios, Promrat, Kittichai, Wands, Jack R.

“…Liver disease remains a leading cause of morbidity and mortality among people living with HIV (PLWH). Emerging data suggest that PLWH are at high risk for…”
Get full text

WNT/β‐catenin signaling and hepatocellular carcinoma by Wands, Jack R., Kim, Miran

Get full text

Wnt signaling and hepatocarcinogenesis: Molecular targets for the development of innovative anticancer drugs by Pez, Floriane, Lopez, Anaïs, Kim, Miran, Wands, Jack R, Caron de Fromentel, Claude, Merle, Philippe

“…Summary Hepatocellular carcinoma (HCC) is one of the most common causes of cancer death worldwide. HCC can be cured by radical therapies if early diagnosis is…”
Get full text

Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis by Promrat, Kittichai, Kleiner, David E., Niemeier, Heather M., Jackvony, Elizabeth, Kearns, Marie, Wands, Jack R., Fava, Joseph L., Wing, Rena R.

“…Nonalcoholic steatohepatitis (NASH) is a chronic progressive liver disease that is strongly associated with obesity. Currently, there is no approved therapy…”
Get full text

Alzheimer's disease is type 3 diabetes-evidence reviewed by de la Monte, Suzanne M, Wands, Jack R

“…Alzheimer's disease (AD) has characteristic histopathological, molecular, and biochemical abnormalities, including cell loss; abundant neurofibrillary tangles;…”
Get full text

Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease by Derdak, Zoltan, Villegas, Kristine A, Harb, Ragheb, Wu, Annie M, Sousa, Aryanna, Wands, Jack R

“…Background & Aims p53 and its transcriptional target miRNA34a have been implicated in the pathogenesis of fatty liver. We tested the efficacy of a p53…”
Get full text

Comprehensive molecular and immunological characterization of hepatocellular carcinoma by Shimada, Shu, Mogushi, Kaoru, Akiyama, Yoshimitsu, Furuyama, Takaki, Watanabe, Shuichi, Ogura, Toshiro, Ogawa, Kosuke, Ono, Hiroaki, Mitsunori, Yusuke, Ban, Daisuke, Kudo, Atsushi, Arii, Shigeki, Tanabe, Minoru, Wands, Jack R., Tanaka, Shinji

“…Hepatocellular carcinoma (HCC) is a heterogeneous disease with various etiological factors, and ranks as the second leading cause of cancer-related mortality…”
Get full text

Unusual Features of Sodium Taurocholate Cotransporting Polypeptide as a Hepatitis B Virus Receptor by Li, Jisu, Zong, Li, Sureau, Camille, Barker, Luke, Wands, Jack R, Tong, Shuping

“…Cell culture (cc)-derived hepatitis B virus (HBV) can infect differentiated HepaRG cells, but efficient infection requires addition of polyethylene glycol…”
Get full text

Acetaldehyde adducts in alcoholic liver disease by Setshedi, Mashiko, Wands, Jack R, Monte, Suzanne M de la

“…Chronic alcohol abuse causes liver disease that progresses from simple steatosis through stages of steatohepatitis, fibrosis, cirrhosis, and eventually hepatic…”
Get full text

Adaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade by Bai, Xuewei, Zhou, Yanmei, Yokota, Yuki, Matsumoto, Yoshihiro, Zhai, Bo, Maarouf, Nader, Hayashi, Hikaru, Carlson, Rolf, Zhang, Songhua, Sousa, Aryanna, Sun, Bei, Ghanbari, Hossein, Dong, Xiaoqun, Wands, Jack R

“…Interactions between tumor and microenvironment determine individual response to immunotherapy. Triple negative breast cancer (TNBC) and hepatocellular…”
Get full text

Prevalence of Steatotic Liver Disease Among US Adults with Rheumatoid Arthritis by Vassilopoulos, Athanasios, Kalligeros, Markos, Vassilopoulos, Stephanos, Shehadeh, Fadi, Benitez, Gregorio, Kaczynski, Matthew, Lazaridou, Ingrid, Promrat, Kittichai, Wands, Jack R, Mylonakis, Eleftherios

“…Background The prevalence of steatotic liver disease (SLD) among patients with rheumatoid arthritis (RA) remains largely unknown. Aims To investigate the…”
Get full text

ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis by Lin, Qiushi, Chen, Xuesong, Meng, Fanzheng, Ogawa, Kosuke, Li, Min, Song, Ruipeng, Zhang, Shugeng, Zhang, Ziran, Kong, Xianglu, Xu, Qinggang, He, Fuliang, Bai, Xuewei, Sun, Bei, Hung, Mien-Chie, Liu, Lianxin, Wands, Jack, Dong, Xiaoqun

“…Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and…”
Get full text

S1377 Prevalence and Risk Factors of NAFLD, High-Risk NASH, and Fibrosis Among Lean US Adults by Kalligeros, Markos, Vassilopoulos, Stephanos, Vassilopoulos, Athanasios, Shehadeh, Fadi, Lazaridou, Ingrid, Mylonakis, Eleftherios, Promrat, Kittichai, Wands, Jack R.

“…Results: From the 15,560 NHANES participants (2017-2020), 1,628 adults, classified as lean, were eligible for our analysis (Table 1). The age-adjusted…”
Get full text

Impact of prior HBV, HAV, and HEV infection on non‐alcoholic fatty liver disease by Vassilopoulos, Stephanos, Kalligeros, Markos, Vassilopoulos, Athanasios, Shehadeh, Fadi, Benitez, Gregorio, Kaczynski, Matthew, Lazaridou, Ingrid, Promrat, Kittichai, Wands, Jack R., Mylonakis, Eleftherios

“…Non‐alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease. The association between prior hepatitis B virus (HBV), hepatitis A virus…”
Get full text

NFIL3 Expression Distinguishes Tissue-Resident NK Cells and Conventional NK-like Cells in the Mouse Submandibular Glands by Erick, Timothy K, Anderson, Courtney K, Reilly, Emma C, Wands, Jack R, Brossay, Laurent

“…The submandibular salivary gland (SMG), a major site of persistent infection for many viruses, contains a large NK cell population. Using NFIL3-deficient mice,…”
Get full text

Alcohol, insulin resistance and the liver-brain axis by de la Monte, Suzanne, Derdak, Zoltan, Wands, Jack R

“…Chronic alcohol exposure inhibits insulin and insulin‐like growth factor signaling in the liver and brain by impairing the signaling cascade at multiple…”
Get full text

Hepatitis C virus and alcohol by Siu, Larry, Foont, Julie, Wands, Jack R

“…This review will focus on the prevalence of hepatitis c virus (HCV) infection in alcoholics with and without liver disease. Evidence will be presented to…”
Get more information

Prevention of Hepatocellular Carcinoma by Wands, Jack R

“…Hepatocellular carcinoma is a significant problem worldwide, and the incidence is increasing in the United States. 1 Approximately 90 to 95 percent of these…”
Get full text

Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease by de la Monte, Suzanne M, Wands, Jack R

“…Interest in characterizing the role of impaired insulin actions in Alzheimer's disease (AD) and vascular dementia is growing exponentially. This review details…”
Get more information

Activation of signal transduction pathways during hepatic oncogenesis by Chung, Waihong, Kim, Miran, de la Monte, Suzanne, Longato, Lisa, Carlson, Rolf, Slagle, Betty L, Dong, Xiaoqun, Wands, Jack R

“…Highlights • Demonstrates the role of viral–cellular protein interactions during oncogenesis. • Sequential activation of tripartite signaling cascades in the…”
Get full text