Search Results - "Wands, J. M"

Distribution and leukocyte contacts of γδ T cells in the lung by Wands, J. M., Roark, Christina L., Aydintug, M. Kemal, Jin, Niyun, Hahn, Youn‐Soo, Cook, Laura, Yin, Xiang, Dal Porto, Joseph, Lahn, Michael, Hyde, Dallas M., Gelfand, Erwin W., Mason, Robert J., O’Brien, Rebecca L., Born, Willi K.

“…Pulmonary γδ T cells protect the lung and its functions, but little is known about their distribution in this organ and their relationship to other pulmonary…”
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Aerosolized anti-T-cell-receptor antibodies are effective against airway inflammation and hyperreactivity by Lahn, Michael, Kanehiro, Arihiko, Hahn, Youn-Soo, Wands, J M, Aydintug, M Kemal, O'Brien, Rebecca L, Gelfand, Erwin W, Born, Willi K

“…Aerosolized monoclonal antibodies (mAbs) specific for T-cell receptors (TCR) were used to manipulate T-cell function in airways of ovalbumin (OVA)-sensitized…”
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gamma delta T-cell receptors: functional correlations by O'Brien, Rebecca L, Roark, Christina L, Jin, Niyun, Kemal Aydintug, M, French, Jena D, Chain, Jennifer L, Wands, J M, Johnston, Molly, Born, Willi K

“…The gamma delta T-cell receptors (TCRs) are limited in their diversity, suggesting that their natural ligands may be few in number. Ligands for gamma delta…”
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gamma delta T cells recognize the insulin B:9-23 peptide antigen when it is dimerized through thiol oxidation by Aydintug, MKemal, Zhang, Li, Wang, Chao, Liang, Dongchun, Wands, J M, Michels, Aaron W, Hirsch, Brooke, Day, Brian J, Zhang, Gongyi, Sun, Deming, Eisenbarth, George S, O'Brien, Rebecca L, Born, Willi K

“…The insulin peptide B:9-23 is a natural antigen in the non-obese diabetic (NOD) mouse model of type 1 diabetes (T1D). In addition to alpha beta T cells and B…”
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γδ T cells recognize the insulin B:9–23 peptide antigen when it is dimerized through thiol oxidation by Kemal Aydintug, M., Zhang, Li, Wang, Chao, Liang, Dongchun, Wands, J.M., Michels, Aaron W., Hirsch, Brooke, Day, Brian J., Zhang, Gongyi, Sun, Deming, Eisenbarth, George S., O’Brien, Rebecca L., Born, Willi K.

“…•Gamma delta T cells specifically respond to the insulin peptide B:9–23.•The response requires dimerization of the peptide via thiol oxidation.•The oxidized…”
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T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB11501-transgenic mice by Chou, Yuan K., Culbertson, Nicole, Rich, Cathleen, LaTocha, Dorian, Buenafe, Abigail C., Huan, Jianya, Link, Jason, Wands, J.M., Born, Willi K., Offner, Halina, Bourdette, Dennis N., Burrows, Gregory G., Vandenbark, Arthur A.

“…The goal of this study was to establish an unlimited and standardized source of humanized myelin peptide‐specific T cells for in vitro testing of biological…”
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gamma delta T Lymphocytes-Selectable Cells Within the Innate System? by Born, Willi K, Jin, Niyun, Aydintug, MKemal, Wands, J M, French, Jena D, Roark, Christina L, O'Brien, Rebecca L

“…Lymphocytes expressing gamma delta T cell receptors (TCR) constitute an entire system of functionally specialized subsets that have been implicated in the…”
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Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not V gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation by Hahn, Youn-Soo, Taube, Christian, Jin, Niyun, Sharp, Laura, Wands, J M, Aydintug, M Kemal, Lahn, Michael, Huber, Sally A, O'Brien, Rebecca L, Gelfand, Erwin W, Born, Willi K

“…Allergic airway inflammation and hyperreactivity are modulated by gammadelta T cells, but different experimental parameters can influence the effects observed…”
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Protective Role of γδ T Cells in Spontaneous Ocular Inflammation by O'BRIEN, Rebecca L, TAYLOR, Molly A, HARTLEY, Jacqueline, NUHSBAUM, Tanja, DUGAN, Steve, LAHMERS, Kevin, KEMAL AYDINTUG, M, WANDS, J. M, ROARK, Christina L, BORN, Willi K

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Distribution and leukocyte contacts of gamma delta T cells in the lung by Wands, J M, Roark, CL, Aydintug, M K, Jin, Niyun, Hahn, Youn-Soo, Cook, L, Yin, Xiang, Porto, J D, Lahn, M, Hyde, D M, Gelfand, E W, Mason, R J, O'Brien, R L, Born, W K

“…Pulmonary gamma delta T cells protect the lung and its functions, but little is known about their distribution in this organ and their relationship to other…”
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V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice by Hahn, Youn-Soo, Taube, Christian, Jin, Niyun, Takeda, Katsuyuki, Park, Jung-Won, Wands, J M, Aydintug, M Kemal, Roark, Christina L, Lahn, Michael, O'Brien, Rebecca L, Gelfand, Erwin W, Born, Willi K

“…The Vgamma4(+) pulmonary subset of gammadelta T cells regulates innate airway responsiveness in the absence of alphabeta T cells. We now have examined the same…”
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Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness by Jin, Niyun, Taube, Christian, Sharp, Laura, Hahn, Youn-Soo, Yin, Xiang, Wands, J M, Roark, Christina L, O'brien, Rebecca L, Gelfand, Erwin W, Born, Willi K

“…Gammadelta T cells suppress airway hyperresponsiveness (AHR) induced in allergen-challenged mice but it is not clear whether the suppression is allergen…”
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The Influence of IgE-Enhancing and IgE-Suppressive γδ T Cells Changes with Exposure to Inhaled Ovalbumin by Huang, Yafei, Jin, Niyun, Roark, Christina L., Aydintug, M. Kemal, Wands, J. M., Huang, Hua, O'Brien, Rebecca L., Born, Willi K.

“…Abstract It has been reported that the IgE response to allergens is influenced by γδ T cells. Intrigued by a study showing that airway challenge of mice with…”
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Role of γδ T Cells in Lung Inflammation by Born, Willi K, Roark, Christina L, Jin, Niyun, Wands, J M, Kemal Aydintug, M, Huang, Yafei, Chain, Jennifer L, Hahn, Youn-Soo, Simonian, Philip L, Fontenot, Andrew P, O'Brien, Rebecca L

“…The resident population of γδ T cells in the normal lung is small but during lung inflammation, γδ T cells can increase dramatically. Histological analysis…”
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Different Potentials of γδ T Cell Subsets in Regulating Airway Responsiveness: Vγ1+ Cells, but Not Vγ4+ Cells, Promote Airway Hyperreactivity, Th2 Cytokines, and Airway Inflammation by Hahn, Youn-Soo, Taube, Christian, Jin, Niyun, Sharp, Laura, Wands, J. M., Aydintug, M. Kemal, Lahn, Michael, Huber, Sally A., O’Brien, Rebecca L., Gelfand, Erwin W., Born, Willi K.

“…Abstract Allergic airway inflammation and hyperreactivity are modulated by γδ T cells, but different experimental parameters can influence the effects…”
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γδ T-cell receptors: functional correlations by O'Brien, Rebecca L, Roark, Christina L, Jin, Niyun, Kemal Aydintug, M, French, Jena D, Chain, Jennifer L, Wands, J.M, Johnston, Molly, Born, Willi K

“…The γδ T-cell receptors (TCRs) are limited in their diversity, suggesting that their natural ligands may be few in number. Ligands for γδTCRs that have thus…”
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Evidence That CD8+ Dendritic Cells Enable the Development of γδ T Cells That Modulate Airway Hyperresponsiveness by Cook, Laura, Miyahara, Nobuaki, Jin, Niyun, Wands, J. M., Taube, Christian, Roark, Christina L., Potter, Terry A., Gelfand, Erwin W., O'Brien, Rebecca L., Born, Willi K.

“…Abstract Airway hyperresponsiveness (AHR), a hallmark of asthma and several other diseases, can be modulated by γδ T cells. In mice sensitized and challenged…”
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Allergic Airway Hyperresponsiveness-Enhancing γδ T Cells Develop in Normal Untreated Mice and Fail to Produce IL-4/13, Unlike Th2 and NKT Cells by Jin, Niyun, Roark, Christina L., Miyahara, Nobuaki, Taube, Christian, Aydintug, M. Kemal, Wands, J. M., Huang, Yafei, Hahn, Youn-Soo, Gelfand, Erwin W., O'Brien, Rebecca L., Born, Willi K.

“…Abstract Allergic airway hyperresponsiveness (AHR) in OVA-sensitized and challenged mice, mediated by allergen-specific Th2 cells and Th2-like invariant NKT…”
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γδ T Lymphocytes—Selectable Cells Within the Innate System? by Born, Willi K., Jin, Niyun, Aydintug, M. Kemal, Wands, J. M., French, Jena D., Roark, Christina L., O’brien, Rebecca L.

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Detection of Cell Surface Ligands for the γδ TCR Using Soluble TCRs by Aydintug, M. Kemal, Roark, Christina L., Yin, Xiang, Wands, J. M., Born, Willi K., O’Brien, Rebecca L.

“…Abstract The natural ligands recognized by γδ TCRs are still largely unknown, in part because immunization does not normally result in Ag-specific γδ T cell…”
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