Search Results - "Wandro, Stephen"
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The Microbiome and Metabolome of Preterm Infant Stool Are Personalized and Not Driven by Health Outcomes, Including Necrotizing Enterocolitis and Late-Onset Sepsis
Published in mSphere (27-06-2018)“…The assembly and development of the gut microbiome in infants have important consequences for immediate and long-term health. Preterm infants represent an…”
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Predictable Molecular Adaptation of Coevolving Enterococcus faecium and Lytic Phage EfV12-phi1
Published in Frontiers in microbiology (31-01-2019)“…Bacteriophages are highly abundant in human microbiota where they coevolve with resident bacteria. Phage predation can drive the evolution of bacterial…”
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A comparison of DNA/RNA extraction protocols for high-throughput sequencing of microbial communities
Published in BioTechniques (01-03-2021)“…One goal of microbial ecology researchers is to capture the maximum amount of information from all organisms in a sample. The recent COVID-19 pandemic, caused…”
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Cervicovaginal Microbiome Composition Is Associated with Metabolic Profiles in Healthy Pregnancy
Published in mBio (25-08-2020)“…Microbes and their metabolic products influence early-life immune and microbiome development, yet remain understudied during pregnancy. Vaginal microbial…”
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Evaluation of the Effect of Storage Methods on Fecal, Saliva, and Skin Microbiome Composition
Published in mSystems (27-04-2021)“…As the number of human microbiome studies expand, it is increasingly important to identify cost-effective, practical preservatives that allow for room…”
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Phage Cocktails Constrain the Growth of Enterococcus
Published in mSystems (30-08-2022)“…Phages that infect pathogenic bacteria present a valuable resource for treating antibiotic-resistant infections. We isolated and developed a collection of 19…”
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Zebra: Static and Dynamic Genome Cover Thresholds with Overlapping References
Published in mSystems (26-10-2022)“…Assigning taxonomy remains a challenging topic in microbiome studies, due largely to ambiguity of reads which overlap multiple reference genomes. With the Web…”
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Signatures of HIV and Major Depressive Disorder in the Plasma Microbiome
Published in Microorganisms (Basel) (01-04-2023)“…Inter-individual differences in the gut microbiome are linked to alterations in inflammation and blood-brain barrier permeability, which may increase the risk…”
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Dosing and Re-Administration of Lentiviral Vector for In Vivo Gene Therapy in Rhesus Monkeys and ADA-Deficient Mice
Published in Molecular therapy. Methods & clinical development (13-03-2020)“…Adenosine deaminase (ADA)-deficient mice and healthy rhesus monkeys were studied to determine the impact of age at treatment, vector dosage, dosing schedule,…”
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Making It Last: Storage Time and Temperature Have Differential Impacts on Metabolite Profiles of Airway Samples from Cystic Fibrosis Patients
Published in mSystems (01-11-2017)“…Metabolites of human or microbial origin have the potential to be important biomarkers of the disease state in cystic fibrosis (CF). Clinical sample collection…”
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Swapping Metagenomics Preprocessing Pipeline Components Offers Speed and Sensitivity Increases
Published in mSystems (26-04-2022)“…Increasing data volumes on high-throughput sequencing instruments such as the NovaSeq 6000 leads to long computational bottlenecks for common metagenomics data…”
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Evaluation of the Effect of Storage Methods on Fecal, Saliva, and Skin Microbiome Composition
Published in mSystems (27-04-2021)“…As the number of human microbiome studies expand, it is increasingly important to identify cost-effective, practical preservatives that allow for room…”
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Microbiome analyses of blood and tissues suggest cancer diagnostic approach
Published in Nature (London) (01-03-2020)“…Systematic characterization of the cancer microbiome provides the opportunity to develop techniques that exploit non-human, microorganism-derived molecules in…”
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Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
Published in Cell (29-09-2022)“…Cancer-microbe associations have been explored for centuries, but cancer-associated fungi have rarely been examined. Here, we comprehensively characterize the…”
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Robustness of cancer microbiome signals over a broad range of methodological variation
Published in Oncogene (05-04-2024)“…In 2020, we identified cancer-specific microbial signals in The Cancer Genome Atlas (TCGA) [ 1 ]. Multiple peer-reviewed papers independently verified or…”
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Retraction Note: Microbiome analyses of blood and tissues suggest cancer diagnostic approach
Published in Nature (London) (18-07-2024)Get full text
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Correction: Robustness of cancer microbiome signals over a broad range of methodological variation
Published in Oncogene (01-05-2024)Get full text
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Cystic Fibrosis-Associated Stenotrophomonas maltophilia Strain-Specific Adaptations and Responses to pH
Published in Journal of bacteriology (01-04-2019)“…The airway fluids of cystic fibrosis (CF) patients contain local pH gradients and are more acidic than those of healthy individuals. pH is a critical factor…”
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RETRACTED ARTICLE: Microbiome analyses of blood and tissues suggest cancer diagnostic approach
Published in Nature (London) (26-03-2020)“…Systematic characterization of the cancer microbiome provides the opportunity to develop techniques that exploit non-human, microorganism-derived molecules in…”
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Abstract 1184: Early-stage lung cancer detection via circulating microbial DNA biomarkers and machine learning classification
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Introduction: Human tissues, including tumors, are extensively colonized by taxonomically diverse microbes. Intra-tumoral microbial activity and…”
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