Search Results - "Wandrer, Franziska"
-
1
TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice
Published in Cell death & disease (31-03-2020)“…Non-alcoholic fatty liver disease (NAFLD) shows an increasing prevalence and is associated with the development of liver fibrosis and cirrhosis as the major…”
Get full text
Journal Article -
2
BH3-only protein expression determines hepatocellular carcinoma response to sorafenib-based treatment
Published in Cell death & disease (26-07-2021)“…Hepatocellular carcinoma (HCC) represents a global health challenge with limited therapeutic options. Anti-angiogenic immune checkpoint inhibitor-based…”
Get full text
Journal Article -
3
miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib
Published in Journal of hepatology (01-11-2017)“…Graphical abstract…”
Get full text
Journal Article -
4
Donor NK and T Cells in the Periphery of Lung Transplant Recipients Contain High Frequencies of Killer Cell Immunoglobulin-Like Receptor-Positive Subsets
Published in Frontiers in immunology (13-12-2021)“…For end-stage lung diseases, double lung transplantation (DLTx) is the ultimate curative treatment option. However, acute and chronic rejection and chronic…”
Get full text
Journal Article -
5
Transjugular diagnostics in acute liver failure including measurements of hepatocentral venous biomarker gradients
Published in Hepatology research (01-10-2018)“…Aim Acute liver failure (ALF) is a syndrome of severe liver injury that may need urgent liver transplantation and is associated with significant risk of death…”
Get full text
Journal Article -
6
Functional activin-HNF4A-coagulation axis in liver progenitor cells determines MELD score and outcome of acute-on-chronic liver failure
Published in Journal of hepatology (01-08-2020)Get full text
Journal Article -
7
-
8
miR-223 represents a biomarker in acute and chronic liver injury
Published in Clinical science (1979) (01-08-2017)“…Dysregulation of miRNAs has been described in tissue and serum from patients with acute and chronic liver diseases. However, only little information on the…”
Get more information
Journal Article -
9
Autophagy alleviates amiodarone-induced hepatotoxicity
Published in Archives of toxicology (01-10-2020)“…Amiodarone is a widely used antiarrhythmic drug that can cause the development of steatohepatitis as well as liver fibrosis and cirrhosis. The molecular…”
Get full text
Journal Article -
10
Follistatin‐controlled activin‐HNF4α‐coagulation factor axis in liver progenitor cells determines outcome of acute liver failure
Published in Hepatology (Baltimore, Md.) (01-02-2022)“…Background and Aims In patients with acute liver failure (ALF) who suffer from massive hepatocyte loss, liver progenitor cells (LPCs) take over key hepatocyte…”
Get full text
Journal Article -
11
-
12
Interferon-Mediated Cytokine Induction Determines Sustained Virus Control in Chronic Hepatitis C Virus Infection
Published in The Journal of infectious diseases (01-03-2016)“…Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and associated complications such as liver cirrhosis and hepatocellular carcinoma…”
Get full text
Journal Article -
13
Back signaling of HLA class I molecules and T/NK cell receptor ligands in epithelial cells reflects the rejection‐specific microenvironment in renal allograft biopsies
Published in American journal of transplantation (01-10-2019)“…The role of endothelial cells in the pathophysiology of antibody‐mediated rejection after renal transplantation has been widely investigated. We expand this…”
Get full text
Journal Article -
14
Identification of distinct secretory patterns and their regulatory networks of ischemia versus reperfusion phases in clinical heart transplantation
Published in Cytokine (Philadelphia, Pa.) (01-01-2022)“…•Distinct inflammatory patterns for ischemic vs. reperfusion phases of HTx.•The ischemic signature comprises MIF, OPN, sVCAM-1, sICAM-1, IGFBP-1, SCGF-ß.•The…”
Get full text
Journal Article -
15
Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis
Published in Cell death & disease (19-01-2018)“…Alcohol abuse is a global health problem causing a substantial fraction of chronic liver diseases. Abundant TGF-β—a potent pro-fibrogenic cytokine—leads to…”
Get full text
Journal Article -
16
Differential effects of Belatacept on virus-specific memory versus de novo allo-specific T cell responses of kidney transplant recipients and healthy donors
Published in Transplant immunology (01-08-2020)“…Belatacept, Nulojix®, inhibits the interaction of CD28 on naïve T cells with B7.1/B7.2 (CD80/86) on antigen presenting cells, leading to T cell…”
Get full text
Journal Article