Search Results - "Wanderley, Alayde Vieira"
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Association between the TPMT3C (rs1142345) Polymorphism and the Risk of Death in the Treatment of Acute Lymphoblastic Leukemia in Children from the Brazilian Amazon Region
Published in Genes (25-09-2020)“…Acute lymphoblastic leukemia (ALL) is the leading cause of death from pediatric cancer worldwide. However, marked ethnic disparities are found in the treatment…”
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2
Influence of Genetic Variations in miRNA and Genes Encoding Proteins in the miRNA Synthesis Complex on Toxicity of the Treatment of Pediatric B-Cell ALL in the Brazilian Amazon
Published in International journal of molecular sciences (23-02-2023)“…Acute lymphoblastic leukemia (ALL) is the most common childhood cancer in the world. Single nucleotide variants (SNVs) in miRNA and genes encoding proteins of…”
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3
Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia
Published in Scientific reports (04-12-2020)“…Aurora kinases (AURKA and AURKB) are mitotic kinases with an important role in the regulation of several mitotic events, and in hematological malignancies,…”
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4
Characterization of pharmacogenetic markers related to Acute Lymphoblastic Leukemia toxicity in Amazonian native Americans population
Published in Scientific reports (24-06-2020)“…Acute Lymphoblastic Leukemia (ALL) is the most common cancer in children. Differences are found among ethnic groups in the results of the treatment of…”
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5
Effect of American genomic ancestry on severe toxicities in children with acute lymphoblastic leukemia in the Amazon region
Published in Discover. Oncology (18-05-2024)“…Background Acute Lymphoblastic Leukemia (ALL) is a neoplasm of the hematopoietic system characterized by a clonal expansion of abnormal lymphocyte precursor…”
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Telomerase ( hTERT ) Overexpression Reveals a Promising Prognostic Biomarker and Therapeutical Target in Different Clinical Subtypes of Pediatric Acute Lymphoblastic Leukaemia
Published in Genes (17-10-2021)“…Acute Lymphoblastic Leukemia (ALL) is a neoplasm of the hematopoietic system defined as a clonal expansion of an abnormal lymphoid precursor cell. It mostly…”
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7
Correlation of Genetic Variants and the Incidence, Prevalence and Mortality Rates of Acute Lymphoblastic Leukemia
Published in Journal of personalized medicine (28-02-2022)“…Acute lymphoblastic leukemia (ALL) is the most common cancer during childhood, representing about 30-35% of cases. Its etiology is complex and not fully…”
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8
Identifying novel genetic alterations in pediatric acute lymphoblastic leukemia based on copy number analysis
Published in Molecular cytogenetics (26-06-2020)“…Copy number variations (CNVs) analysis may reveal molecular biomarkers and provide information on the pathogenesis of acute lymphoblastic leukemia (ALL). We…”
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Association of genes ARID5B, CEBPE and folate pathway with acute lymphoblastic leukemia in a population from the Brazilian Amazon region
Published in Leukemia research reports (2020)“…Acute Lymphoblastic Leukemia (ALL) is the most common childhood neoplasia. Studies have shown that susceptibility to ALL may be modulated by genetic variables…”
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10
Successful Outcomes of Children Simultaneously Diagnosed with Acute Myeloid Leukemia and Covid-19: The Role of a Mild Chemotherapeutic Induction Regimen
Published in Blood (05-11-2020)“…Introduction: Children with newly diagnosed acute myeloid leukemia (AML) may have a high early mortality when resources are limited by infrastructure or by a…”
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11
Identification of NUDT15 gene variants in Amazonian Amerindians and admixed individuals from northern Brazil
Published in PloS one (15-04-2020)“…The nudix hydrolase 15 (NUDT15) gene acts in the metabolism of thiopurine, by catabolizing its active metabolite thioguanosine triphosphate into its…”
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12
Desempenho do PRISM III e do PIM 2 em unidade de terapia intensiva pediátrica oncológica
Published in Revista Brasileira de Terapia Intensiva (01-04-2021)“…RESUMO Objetivo: Avaliar o desempenho do Pediatric Risk of Mortality (PRISM) III e do Pediatric Index of Mortality (PIM) 2 em unidade de terapia intensiva…”
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13
OSTEOSSARCOMA IN A 14-YEAR-OLD GIRL
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-08-2017)Get full text
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14
Pharmacogenomics and variations in the risk of toxicity during the consolidation/maintenance phases of the treatment of pediatric B-cell leukemia patients from an admixed population in the Brazilian Amazon
Published in Leukemia research (01-11-2018)“…•During the consolidation phase, 45.5% of the patients presented at least one episode of toxicity.•During the maintenance phase, 19.8% of the patients suffered…”
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15
Risk of infectious toxicity associated with polymorphism in GSTP1 in children with acute lymphoblastic leukemia in a population of Amazonia
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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16
Performance of PRISM III and PIM 2 scores in a cancer pediatric intensive care unit
Published in Revista Brasileira de terapia intensiva (01-01-2021)“…To assess the performance of Pediatric Risk of Mortality (PRISM) III and Pediatric Index of Mortality (PIM) 2 scores in the pediatric intensive care unit. A…”
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Pediatric Acute Promyelocytic Leukemia: Epidemiology, Molecular Features, and Importance of GST-Theta 1 in Chemotherapy Response and Outcome
Published in Frontiers in oncology (19-03-2021)“…Previous studies have suggested a variation in the incidence of acute promyelocytic leukemia (APL) among the geographic regions with relatively higher…”
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Childhood Myeloid Neoplasms With PTPN11 Mutations in Brazil
Published in Clinical lymphoma, myeloma and leukemia (01-08-2020)Get full text
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19
Amplificação dos genes ADAM3A, ADAM6 e DMBT1 em pacientes com Leucemia Linfoblástica Aguda
Published in Semina. Ciências biológicas e da saúde (16-02-2018)“…A leucemia linfoblástica aguda (LLA), assim como outros tipos de câncer, é um processo de múltiplas etapas caracterizado por alterações iniciais e secundárias…”
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