Search Results - "Wan, Zhengqing"
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Charge-Dependent Regulation in DNA Adsorption on 2D Clay Minerals
Published in Scientific reports (02-05-2019)“…DNA purification is essential for the detection of human clinical specimens. A non-destructive, controllable, and low reagent consuming DNA extraction method…”
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Integrative Multi-Omics Analysis Reveals Candidate Biomarkers for Oral Squamous Cell Carcinoma
Published in Frontiers in oncology (14-01-2022)“…Oral squamous cell carcinoma (OSCC) is one of the most common types of cancer worldwide. Due to the lack of early detection and treatment, the survival rate of…”
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Effects of Commonly Used Pesticides in China on the Mitochondria and Ubiquitin-Proteasome System in Parkinson's Disease
Published in International journal of molecular sciences (23-11-2017)“…Evidence continues to accumulate that pesticides are the leading candidates of environmental toxins that may contribute to the pathogenesis of Parkinson's…”
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Unidirectional alteration of methylation and hydroxymethylation at the promoters and differential gene expression in oral squamous cell carcinoma
Published in Frontiers in genetics (12-10-2023)“…Background: Oral squamous cell carcinoma (OSCC) is one of the most common types of cancer worldwide. Although overall losses of 5-methylcytosine (5mC) and…”
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Characterization of Mitochondrial DNA Methylation of Alzheimer's Disease in Plasma Cell-Free DNA
Published in Diagnostics (Basel) (01-07-2023)“…Noninvasive diagnosis of Alzheimer's disease (AD) is important for patients. Significant differences in the methylation of mitochondrial DNA (mtDNA) were found…”
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Targeted Sequencing of Genomic Repeat Regions Detects Circulating Cell-free Echinococcus DNA
Published in PLoS neglected tropical diseases (01-03-2020)“…Echinococcosis is a chronic zoonosis caused by tapeworms of the genus Echinococcus. Treatment of the disease is often expensive and complicated, sometimes…”
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Mitochondrial DNA heteroplasmy rises in substantial nigra of aged PINK1 KO mice
Published in Biochemical and biophysical research communications (22-01-2020)“…Mutations in PINK1 and Parkin result in early-onset autosomal recessive Parkinson’s disease (PD). PINK1/Parkin pathway maintain mitochondrial function by…”
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BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy
Published in The Journal of biological chemistry (07-10-2016)“…Mutations in PINK1 (PTEN-induced putative kinase 1) cause early onset familial Parkinson's disease (PD). PINK1 accumulates on the outer membrane of damaged…”
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ELMOD3, a novel causative gene, associated with human autosomal dominant nonsyndromic and progressive hearing loss
Published in Human genetics (01-04-2018)“…Autosomal dominant nonsyndromic hearing loss (ADNSHL) is a highly genetically heterogeneous disorder. Up to date only approximately 37 ADNSHL-causing genes…”
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