Search Results - "Wan, Zesheng"

TGFβR1 Blockade with Galunisertib (LY2157299) Enhances Anti-Neuroblastoma Activity of the Anti-GD2 Antibody Dinutuximab (ch14.18) with Natural Killer Cells by Tran, Hung C, Wan, Zesheng, Sheard, Michael A, Sun, Jianping, Jackson, Jeremy R, Malvar, Jemily, Xu, Yibing, Wang, Larry, Sposto, Richard, Kim, Eugene S, Asgharzadeh, Shahab, Seeger, Robert C

“…Immunotherapy of high-risk neuroblastoma using the anti-GD2 antibody dinutuximab induces antibody-dependent cell-mediated cytotoxicity (ADCC). Galunisertib, an…”
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Mechanism of Synergy of N-(4-Hydroxyphenyl)Retinamide and ABT-737 in Acute Lymphoblastic Leukemia Cell Lines: Mcl-1 Inactivation by Kang, Min H., Wan, Zesheng, Kang, Yun Hee, Sposto, Richard, Reynolds, C. Patrick

“…Background ABT-737 is a pan-Bcl-2 inhibitor that has a wide range of single-agent activity against acute lymphoblastic leukemia (ALL) cell lines and…”
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Molecular mechanisms of Guadecitabine induced FGFR4 down regulation in alveolar rhabdomyosarcomas by Darvishi, Emad, Slemmons, Katherine, Wan, Zesheng, Mitra, Sheetal, Hou, Xiaogang, Hugues Parmentier, Jean, Eddie Loh, Yong-Hwee, Helman, Lee J.

“…Fibroblast growth factor receptor 4 (FGFR4) aberrant expression and activity have been linked to the pathogenesis of a variety of cancers including…”
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Histone Deacetylase 1 Gene Expression and Sensitization of Multidrug-Resistant Neuroblastoma Cell Lines to Cytotoxic Agents by Depsipeptide by Keshelava, Nino, Davicioni, Elai, Wan, Zesheng, Ji, Lingyun, Sposto, Richard, Triche, Timothy J., Reynolds, C. Patrick

“…Background Genes that are overexpressed in multidrug-resistant neuroblastomas relative to drug-sensitive neuroblastomas may provide targets for modulating drug…”
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Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia by Ruan, Yongsheng, Kim, Hye Na, Ogana, Heather A, Wan, Zesheng, Hurwitz, Samantha, Nichols, Cydney, Abdel-Azim, Nour, Coba, Ariana, Seo, Seyoung, Loh, Yong-Hwee Eddie, Gang, Eun Ji, Abdel-Azim, Hisham, Hsieh, Chih-Lin, Lieber, Michael R, Parekh, Chintan, Pal, Dhananjaya, Bhojwani, Deepa, Durden, Donald L, Kim, Yong-Mi

“…The PI3K/Akt pathway-and in particular PI3Kδ-is known for its role in drug resistant B-cell acute lymphoblastic leukemia (B-ALL) and it is often upregulated in…”
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Characterizing the Motility of Chemotherapeutics-Treated Acute Lymphoblastic Leukemia Cells by Time-Lapse Imaging by Liu, Hsiao-Chuan, Gang, Eun Ji, Kim, Hye Na, Ruan, Yongsheng, Ogana, Heather, Wan, Zesheng, Bönig, Halvard, Shung, K Kirk, Kim, Yong-Mi

“…Drug resistance is an obstacle in the therapy of acute lymphoblastic leukemia (ALL). Whether the physical properties such as the motility of the cells…”
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Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma by Gutova, Margarita, Goldstein, Leanne, Metz, Marianne, Hovsepyan, Anahit, Tsurkan, Lyudmila G., Tirughana, Revathiswari, Tsaturyan, Lusine, Annala, Alexander J., Synold, Timothy W., Wan, Zesheng, Seeger, Robert, Anderson, Clarke, Moats, Rex A., Potter, Philip M., Aboody, Karen S.

“…Despite improved survival for children with newly diagnosed neuroblastoma (NB), recurrent disease is a significant problem, with treatment options limited by…”
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TBL1 Inhibitor, Tegavivint, Supresses Cell Survival and Promotes Sensitivity to Chemotherapy in ALL and AML by Hurwitz, Samantha, Ogana, Heather, Wan, Zesheng, Navid, Fariba, Bhojwani, Deepa, Kim, Yong-Mi

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Activated Natural Killer Cells in Combination with Anti-GD2 Antibody Dinutuximab Improve Survival of Mice after Surgical Resection of Primary Neuroblastoma by Barry, Wesley E, Jackson, Jeremy R, Asuelime, Grace E, Wu, Hong-Wei, Sun, Jianping, Wan, Zesheng, Malvar, Jemily, Sheard, Michael A, Wang, Larry, Seeger, Robert C, Kim, Eugene S

“…Immunotherapy of neuroblastoma that remains after myeloablative chemotherapy with anti-GD2 antibody dinutuximab has increased the two-year event-free and…”
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The Role of Integrin Beta-1 in the Chemoresistance of Acute Myeloid Leukemia by Ogana, Heather, Hurwitz, Samantha, Wan, Zesheng, Kim, Hye Na, Jambon, Samy, Abdel-Azim, Hisham, Huang, Miller, Babak, Moghimi, Heisterkamp, Nora, Carbonell, Anne-Marie, Parekh, Chintan, Konopleva, Marina, Bhojwani, Deepa, Kim, Yong-Mi

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Lenalidomide overcomes suppression of human natural killer cell anti-tumor functions by neuroblastoma microenvironment-associated IL-6 and TGFβ1 by Xu, Yibing, Sun, Jianping, Sheard, Michael A., Tran, Hung C., Wan, Zesheng, Liu, Wei Yao, Asgharzadeh, Shahab, Sposto, Richard, Wu, Hong Wei, Seeger, Robert C.

“…Background Treatment for children with high-risk neuroblastoma with anti-disialoganglioside mAb ch14.18, IL-2, and GM-CSF plus 13- cis -retinoic acid after…”
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Lenalidomide overcomes suppression of human natural killer cell anti-tumor functions by neuroblastoma microenvironment-associated IL-6 and TGF beta 1 by Xu, Yibing, Sun, Jianping, Sheard, Michael A, Tran, Hung C, Wan, Zesheng, Liu, Wei Yao, Asgharzadeh, Shahab, Sposto, Richard, Wu, Hong Wei, Seeger, Robert C

“…Background: Treatment for children with high-risk neuroblastoma with anti-disialoganglioside mAb ch14.18, IL-2, and GM-CSF plus 13-cis-retinoic acid after…”
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Abstract 5920: Inhibition of TBL1 and β-catenin interaction sensitizes acute lymphoblastic leukemia to chemotherapy by Hurwitz, Samantha, Friedmann, Rachel, Fourfouris, Tatiana, Lee, Ki Jun, Wan, Zesheng, Parekh, Chintan, Navid, Fariba, Bhojwani, Deepa, Holloway, Kimberly, Kim, Yong-Mi

“…BACKGROUND: Relapse of T-cell acute lymphoblastic leukemia (T-ALL) and B-cell acute lymphoblastic leukemia (B-ALL) post-chemotherapy or post-immunotherapy…”
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Effective Reduction of Metastasis and Improved Survival by Combining Activated Natural Killer Cells and Anti-GD2 Antibody in Chemo-Resistant Neuroblastoma by Barry, Wesley, Jackson, Jeremy R., Asuelime, Grace E., Wan, Zesheng, Wu, Hong-wei, Sun, Jianping, Wang, Larry, Seeger, Robert C., Kim, Eugene S.

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634. Translation of a Neural Stem Cell-Mediated Enzyme/Prodrug Gene Therapy for Metastatic Neuroblastoma by Gutova, Margarita, Wan, Zesheng, Hovsepyan, Anahit, Tsurkan, Lyudmila S., Metz, Marianne, Synold, Timothy W., Seeger, Robert, Anderson, Clarke, Potter, Philip M., Moats, Rex, Aboody, Karen S.

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STEM-01NEURAL STEM CELL-MEDIATED ENZYME/PRODRUG THERAPY FOR NEUROBLASTOMA: TRANSLATION TO THE CLINIC by Gutova, Margarita, Goldstein, Leanne, Metz, Marianne, Hovsepyan, Anahit, Tsurkan, Lyudmila, Tirughana, Revathiswari, Wan, Zesheng, Synold, Timothy, Seegar, Robert, Anderson, Clarke, Potter, Philip, Moats, Rex, Aboody, Karen

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Lenalidomide overcomes suppression of human natural killer cell anti-tumor functions by neuroblastoma microenvironment-associated IL-6 and TGF[beta]1 by Xu, Yibing, Sun, Jianping, Sheard, Michael A, Tran, Hung C, Wan, Zesheng, Liu, Wei Yao, Asgharzadeh, Shahab, Sposto, Richard, Wu, Hong Wei, Seeger, Robert C

“…Treatment for children with high-risk neuroblastoma with anti-disialoganglioside mAb ch14.18, IL-2, and GM-CSF plus 13-cis-retinoic acid after myeloablative…”
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Epithelial-Mesenchymal Interactions Are Linked to Neovascularization by Schwarz, Margaret A, Wan, ZeSheng, Liu, Jie, Lee, Matthew K

“…Lung morphogenesis is dependent on interactions between mesenchymal and epithelial cells. We have previously demonstrated that inhibition of neovascularization…”
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