Search Results - "Wan, Youyang"
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Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications
Published in ACS applied materials & interfaces (03-03-2021)“…Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have abilities to bind to specific target molecules that rival those of…”
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A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice
Published in Advanced science (01-07-2020)“…Several virtual screening models are proposed to screen small molecules only targeting primary miRNAs without selectivity. Few attempts have been made to…”
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Self‐Healing Electronics for Prognostic Monitoring of Methylated Circulating Tumor DNAs
Published in Advanced materials (Weinheim) (01-02-2023)“…Methylated circulating DNAs (ctDNAs) have recently been reported as a promising biomarker for early cancer diagnostics, but limited tools are currently…”
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Sequencing-free Analysis of Multiple Methylations on Gene-Specific mRNAs
Published in Journal of the American Chemical Society (06-04-2022)“…RNA epigenetics is a new layer of mechanism to regulate gene expression, but limited techniques are available to profile the status of mRNA modifications…”
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