Search Results - "Wan, Kangkang"
-
1
The Jujube Genome Provides Insights into Genome Evolution and the Domestication of Sweetness/Acidity Taste in Fruit Trees
Published in PLoS genetics (01-12-2016)“…Jujube (Ziziphus jujuba Mill.) belongs to the Rhamnaceae family and is a popular fruit tree species with immense economic and nutritional value. Here, we…”
Get full text
Journal Article -
2
When will the battle against novel coronavirus end in Wuhan: A SEIR modeling analysis
Published in Journal of global health (01-06-2020)“…Recent outbreak of 2019-nCoV in Wuhan raised serious public health concerns. By February 15, 2020 in Wuhan, the total number of confirmed infection cases has…”
Get full text
Journal Article -
3
Genome-wide methylation profiling identified methylated KCNA3 and OTOP2 as promising diagnostic markers for esophageal squamous cell carcinoma
Published in Chinese medical journal (20-07-2024)“…Early detection of esophageal squamous cell carcinoma (ESCC) can considerably improve the prognosis of patients. Aberrant cell-free DNA (cfDNA) methylation…”
Get full text
Journal Article -
4
Plasma methylated GNB4 and Riplet as a novel dual-marker panel for the detection of hepatocellular carcinoma
Published in Epigenetics (01-12-2024)“…Early detection of hepatocellular carcinoma (HCC) can greatly improve the survival rate of patients. We aimed to develop a novel marker panel based on…”
Get full text
Journal Article -
5
The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer
Published in BMC gastroenterology (28-02-2022)“…Methylated SDC2 and TFPI2 are widely used for colorectal cancer (CRC) detection. However, they often miss some CRCs, which directly diminishes the sensitivity…”
Get full text
Journal Article -
6
Identification of two methylated fragments of an SDC2 CpG island using a sliding window technique for early detection of colorectal cancer
Published in FEBS open bio (01-07-2021)“…Colorectal cancer (CRC) is one of the most common cancer types globally with a 5‐year survival rate of < 50% in China. Aberrant DNA methylation is one of the…”
Get full text
Journal Article -
7
Genome-wide methylation profiling identify hypermethylated HOXL subclass genes as potential markers for esophageal squamous cell carcinoma detection
Published in BMC medical genomics (29-11-2022)“…Numerous studies have revealed aberrant DNA methylation in esophageal squamous cell carcinoma (ESCC). However, they often focused on the partial genome, which…”
Get full text
Journal Article -
8
Non-invasive diagnosis of esophageal cancer by a simplified circulating cell-free DNA methylation assay targeting OTOP2 and KCNA3: a double-blinded, multicenter, prospective study
Published in Journal of hematology and oncology (18-06-2024)“…Esophageal cancer (EC) is a highly lethal disease lacking early detection approaches. We previously identified that OTOP2 and KCNA3 were specifically…”
Get full text
Journal Article -
9
DNA methylation and gene expression profiling reveal potential association of retinol metabolism related genes with hepatocellular carcinoma development
Published in PeerJ (San Francisco, CA) (23-08-2024)“…Aberrant DNA methylation patterns play a critical role in the development of hepatocellular carcinoma (HCC). However, the molecular mechanisms associated with…”
Get full text
Journal Article -
10
Hypermethylated CDO1 and ZNF454 in Cytological Specimens as Screening Biomarkers for Endometrial Cancer
Published in Frontiers in oncology (28-04-2022)“…We aimed to estimate the diagnostic value of DNA methylation levels in cytological samples of endometrial cancer (EC) and atypical hyperplasia (AH). Two…”
Get full text
Journal Article -
11
Methylation of SDC2 / TFPI2 and Its Diagnostic Value in Colorectal Tumorous Lesions
Published in Frontiers in molecular biosciences (22-12-2021)“…methylation is a feasible biomarker for colorectal cancer detection. Its specificity for colorectal cancer is higher than 90%, but the sensitivity is normally…”
Get full text
Journal Article -
12
Removing PCR for the elimination of undesired DNA fragments cycle by cycle
Published in Scientific reports (29-07-2013)“…A novel removing polymerase chain reaction (R-PCR) technique was developed, which can eliminate undesired genes, cycle by cycle, with efficiencies of 60.9%…”
Get full text
Journal Article